發(fā)布時間：2018-06-19 22:56

  本文選題：血管性認(rèn)知障礙 + 中醫(yī)藥治療　； 參考：《遼寧中醫(yī)藥大學(xué)》2017年碩士論文

【摘要】：目的:將近十年中醫(yī)藥治療血管性認(rèn)知障礙文獻(xiàn)研究所獲得的本病辨證治療及用藥規(guī)律與導(dǎo)師應(yīng)用補(bǔ)腎化痰活血法治療本病的臨床經(jīng)驗相對比,以文獻(xiàn)研究結(jié)果驗證臨床用藥,并拓寬治療思路,為臨床用藥提供指導(dǎo),以求在今后的臨床實(shí)踐中獲得更好的療效。材料與方法:收集中醫(yī)藥治療血管性認(rèn)知障礙的臨床研究文獻(xiàn)106篇,整理所收集文獻(xiàn)的辨證治療及用藥情況,建立相關(guān)數(shù)據(jù)庫,以證素辨證理論為依據(jù),并應(yīng)用Microsoft Excel軟件對數(shù)據(jù)進(jìn)行處理,分析文獻(xiàn)治療本病的辨證治療及用藥規(guī)律;基于臨床實(shí)踐,總結(jié)劉君教授運(yùn)用補(bǔ)腎化痰活血法治療血管性認(rèn)知障礙的臨床經(jīng)驗。結(jié)果:1.本研究納入的106篇文獻(xiàn)中,共涉及45種證型、16項通用證素、21種治法及150味中藥。其中,最常見的證型為腎精虧虛兼痰瘀阻滯證,常見的病性證素及其所占比重依次為血瘀(71.70%)、痰(43.40%)、精虧(42.45%),最常見的病位證素為腎;常用治法及其所占比重依次為:活血化瘀(96.23%)、健脾化痰(47.17%)、補(bǔ)腎益精(38.68%)。2.最常使用的單味藥為石菖蒲。3.所涉及的150味中藥中,藥性分布為:溫(48.97%)、寒(24.25%)、平(22.20%)、涼(3.64%)、熱(0.93%);藥味分布為:甘(29.78%)、苦(28.42%)、辛(24.94%)、咸(7.78%)、酸(4.30%)、澀(3.30%)、淡(1.47%);多入肝經(jīng)(24.60%)、心經(jīng)(15.92%)、腎經(jīng)(13.58%)及脾經(jīng)(13.35%);根據(jù)功效分類多為活血化瘀藥(20.52%)、補(bǔ)血藥(10.45%)及補(bǔ)氣藥(10.17%)。4.補(bǔ)腎化痰活血法治療血管性認(rèn)知障礙療效確切。結(jié)論:血管性認(rèn)知障礙的發(fā)生與腎精虧虛、痰濁、瘀血密切相關(guān),且文獻(xiàn)研究結(jié)果及導(dǎo)師臨床經(jīng)驗均表明以補(bǔ)腎益精、健脾化痰、活血化瘀為治療原則選方遣藥治療本病,療效肯定,具有標(biāo)本兼治的優(yōu)勢。
[Abstract]:Objective: to compare the clinical experience of TCM in treating vascular cognitive disorder and its clinical experience compared with the clinical experience of tutor in treating this disease with the method of tonifying kidney and removing phlegm and activating blood circulation, and to verify the clinical use of drugs with the results of literature study. And broaden the treatment ideas to provide guidance for clinical use, in order to obtain better results in clinical practice in the future. Materials and methods: 106 clinical literatures were collected on the treatment of vascular cognitive impairment with traditional Chinese medicine (TCM), the treatment of syndrome differentiation and medication were sorted out, and the relevant database was established, which was based on the theory of syndrome differentiation. Microsoft Excel software was used to process the data and analyze the syndrome differentiation and drug use rule of literature treatment of this disease. Based on the clinical practice, Professor Liu Jun summarized the clinical experience of treating vascular cognitive disorder with the method of tonifying kidney, removing phlegm and activating blood circulation. The result is 1: 1. In 106 articles, there were 45 syndromes, 16 general syndromes, 21 treatments and 150 kinds of traditional Chinese medicine. The most common syndromes were deficiency of kidney essence and phlegm and blood stasis block. The most common syndromes and their proportion were blood stasis 71.70g, phlegm 43.40g, essence deficiency 42.45. the most common syndromes were kidney. The common treatment methods and their proportion were as follows: promoting blood circulation and removing blood stasis: 96.23C; invigorating spleen and resolving phlegm 47.17; tonifying the kidney and tonifying essence 38.68; The most commonly used single drug is Acorus calamus. Of the 150 herbs involved, 鑽，

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