慢阻肺急性加重與中醫(yī)體質(zhì)的相關(guān)性研究
本文選題:慢性阻塞性肺疾病急性加重 + 中醫(yī)體質(zhì)特征 ; 參考:《山東中醫(yī)藥大學》2016年碩士論文
【摘要】:目的:本研究探討慢性阻塞性肺疾病急性加重時的臨床指標與中醫(yī)體質(zhì)特征的相關(guān)性,進而從中醫(yī)體質(zhì)學角度出發(fā),因人制宜,分析慢性阻塞性肺疾病急性加重發(fā)病機制,指導臨床中醫(yī)辨證論治及對穩(wěn)定期慢性阻塞性肺疾病患者進行體質(zhì)調(diào)理,以減少慢性阻塞性肺疾病急性加重發(fā)作次數(shù),改善患者生活質(zhì)量,延緩病情進展,改善預(yù)后。方法:首先收集山東省中醫(yī)院肺病科病房2014年7月至2015年7月就診的慢性阻塞性肺疾病急性加重患者病歷資料。其次,采集患者年齡、性別、體重指數(shù)等個人信息,發(fā)病季節(jié),病程,并發(fā)癥,mMRC評分,CAT評分,體質(zhì)等相關(guān)信息。運用統(tǒng)計學方法進行統(tǒng)計分析,總結(jié)慢性阻塞性肺疾病急性加重時的相關(guān)指標與中醫(yī)體質(zhì)的相關(guān)規(guī)律。結(jié)果:患者氣虛體質(zhì)39例、痰濕體質(zhì)32例、陰虛體質(zhì)15例、濕熱體質(zhì)14例,占總?cè)藬?shù)80.7%。年齡集中在60-80歲,占72.0%,其中,男性占69.5%,女性30.5%,吸煙者占51.7%。體重指數(shù)22.15±4.41kg/m2,病程5.99±6.001年,56.0%秋冬季急性加重,發(fā)病多見痰濁阻肺證(25.4%)、痰熱壅肺證(23.7%)、肺腎氣陰兩虛證(21.2%)。結(jié)論:中老年男性,吸煙者,較易于秋冬季發(fā)生慢阻肺急性加重;颊咭詺馓擉w質(zhì)、痰濕體質(zhì)、陰虛體質(zhì)、濕熱體質(zhì)多見,痰濕體質(zhì)與瘀血體質(zhì)的體重指數(shù)較高。不同體質(zhì)的性別、年齡、病程、發(fā)病季節(jié)差異性無統(tǒng)計學意義。不同體質(zhì)類型的慢阻肺急性發(fā)作期患者的中醫(yī)證候不同。
[Abstract]:Objective: to investigate the correlation between clinical indexes and TCM physique characteristics in acute exacerbation of chronic obstructive pulmonary disease (COPD), and to analyze the pathogenesis of acute exacerbation of COPD from the point of view of TCM physique. In order to reduce the times of acute exacerbation of chronic obstructive pulmonary disease (COPD), improve the quality of life of patients, delay the progress of the disease and improve the prognosis. Methods: the medical records of patients with acute exacerbation of chronic obstructive pulmonary disease (COPD) from July 2014 to July 2015 were collected. Secondly, we collected personal information, such as age, sex, body mass index, onset season, course of disease, complication mMRC score, cat score, physique and so on. Statistical analysis was used to summarize the correlation between the indexes of chronic obstructive pulmonary disease (COPD) and TCM constitution in acute exacerbation of chronic obstructive pulmonary disease (COPD). Results: there were 39 cases of qi deficiency, 32 cases of phlegm dampness, 15 cases of yin deficiency and 14 cases of dampness and heat. The age was 60-80 years old (72.0%), of which the male accounted for 69.5%, the female 30.5% and the smoker 51.7%. The body mass index was 22.15 鹵4.41 kg / m ~ 2, the course of disease was 5.99 鹵6.001 ~ 56.0% acute exacerbation in autumn and winter, the phlegm turbid and obstructing lung syndrome was 25.4N, the phlegm heat obstructing lung syndrome was 23.7m ~ (2) and the syndrome of deficiency of lung and kidney qi and yin was 21.2%. Conclusion: middle-aged men and smokers are more likely to develop acute exacerbation of COPD in autumn and winter. Qi-deficiency, phlegm-dampness, yin deficiency, damp-heat, phlegm-dampness and blood stasis were more common in patients. There was no significant difference in sex, age, course and season of disease among different physique. The TCM syndromes of patients with chronic obstructive pulmonary disease (COPD) with different physique types are different.
【學位授予單位】:山東中醫(yī)藥大學
【學位級別】:碩士
【學位授予年份】:2016
【分類號】:R259
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