本文選題：當歸地黃飲 + 經(jīng)間期出血��； 參考：《長春中醫(yī)藥大學(xué)》2016年碩士論文

【摘要】：目的:通過對當歸地黃飲加減治療腎陰虛型經(jīng)間期出血的臨床資料進行分析,從而為當歸地黃飲加減治療本病的臨床推廣應(yīng)用提供科學(xué)依據(jù)。方法:本研究在長春中醫(yī)藥大學(xué)的婦科門診開展,使用隨機、藥物平行對照設(shè)計方法,將符合納入病例標準的72例患者平均分成治療組和對照組。治療組給予當歸地黃飲加減,于月經(jīng)周期第7天開始連服10劑,日1劑,中藥免煎顆粒,藥液混合,早晚各1次;對照組給予九芝堂六味地黃丸口服,與治療組相同時間開始連服10天,一次12丸,早晚各1次。每用藥1個月經(jīng)周期后進行癥狀積分評定和療效評價,觀察止血效果和治療前后的癥狀積分的變化,綜合以上分析結(jié)果,評估當歸地黃飲加減的臨床應(yīng)用意義。結(jié)果:(1)治療組的臨床療效總有效率優(yōu)于對照組。(2)治療組止血效果優(yōu)于對照組。(3)治療后兩組中醫(yī)臨床癥狀積分均較前明顯下降,差異具有顯著統(tǒng)計學(xué)意義(P0.01);且治療后治療組緩解癥狀效果優(yōu)于對照組。(4)治療后治療組腰膝酸軟、頭暈耳鳴、五心煩熱、夜寐不寧的患者例數(shù)明顯減少或癥狀明顯減輕,差異具有統(tǒng)計學(xué)意義(P0.05);而大便干燥、小便短黃的患者例數(shù)或病情程度無較大變化,差異無統(tǒng)計學(xué)意義(P0.05)。(5)兩組在治療過程中未出現(xiàn)與藥物有關(guān)的不良反應(yīng)。由此可見,當歸地黃飲加減用于腎陰虛型經(jīng)間期出血的治療效果明顯優(yōu)于對照組。結(jié)論:當歸地黃飲加減治療組與九芝堂六味地黃丸對照組治療腎陰虛型經(jīng)間期出血,治療組在總療效、止血效果的比較上優(yōu)于對照組。由此得出,當歸地黃飲加減治療經(jīng)間期出血腎陰虛證安全、有效,可明顯改善患者臨床癥狀和出血情況,降低中醫(yī)臨床癥狀總積分,改善腎陰虛導(dǎo)致伴隨癥狀,說明本方具有良好的止血效果,療效確切,未見不良反應(yīng)與其他副作用,有在臨床上廣泛應(yīng)用的可行性和實踐意義。
[Abstract]:Objective: to analyze the clinical data of the treatment of interphase hemorrhage of kidney yin deficiency type by adding and subtracting Angelica Dihuang decoction, so as to provide a scientific basis for the clinical popularization and application of the addition and subtraction of Angelica Dihuang decoction for the treatment of this disease. Methods: the study was carried out in the department of gynecology of Changchun University of traditional Chinese Medicine. The 72 patients who met the criteria were divided into two groups: treatment group and control group. The treatment group was given the addition and subtraction of Danggui Dihuang decoction, and on the 7th day of menstrual cycle, the treatment group began to take 10 doses, one dose per day, and the traditional Chinese medicine without decoction granules and liquid mixture, one time in the morning and evening, while the control group was given Jiuzitang Liuwei Dihuang pills orally. The same time as the treatment group began to take 10 days, 12 pills once, 1 in the morning and evening. After one menstrual cycle, the symptom score and curative effect were evaluated, the effect of hemostasis and the change of symptom score before and after treatment were observed, and the clinical application significance of the addition and subtraction of Danggui Dihuang decoction was evaluated by synthesizing the above analysis results. Results the total effective rate of the treatment group was better than that of the control group. (2) the hemostatic effect of the treatment group was better than that of the control group. The difference was statistically significant (P 0.01), and the effect of relieving symptoms in the treatment group was better than that in the control group. (4) after treatment, the patients in the treatment group were obviously reduced in the number of patients with sore waist and knee, dizziness and tinnitus, five-upset heat, restless sleep, or symptoms. The difference was statistically significant (P 0.05), but there was no significant change in the number of patients with dry stool and short yellow urine (P 0.05). It can be seen that the effect of the addition and subtraction of Danggui Dihuang decoction in the treatment of intermenstrual hemorrhage of kidney yin deficiency type is better than that of the control group. Conclusion: Danggui Dihuang decoction plus and subtraction treatment group and Jiuzitang Liuwei Dihuang pill control group in the treatment of kidney yin deficiency type of intermenstrual hemorrhage, the treatment group in the total efficacy, hemostatic effect is better than the control group. It is concluded that it is safe and effective to treat the syndrome of deficiency of kidney yin in the treatment of intermenstrual hemorrhage with Dihuang decoction, which can obviously improve the clinical symptoms and bleeding of patients, reduce the total score of clinical symptoms of traditional Chinese medicine, and improve the accompanying symptoms caused by deficiency of kidney yin. The results showed that the prescription had good hemostatic effect, no adverse reactions and other side effects, and had the feasibility and practical significance of wide application in clinical practice.
【學(xué)位授予單位】：長春中醫(yī)藥大學(xué)
【學(xué)位級別】：碩士
【學(xué)位授予年份】：2016
【分類號】：R271.11

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本文編號：2013301