本文選題：電針 + 圍絕經(jīng)期綜合征��； 參考：《安徽中醫(yī)藥大學(xué)》2016年碩士論文

【摘要】：1目的通過觀察電針不同頻次的治療對圍絕經(jīng)期綜合征患者癥狀積分和性激素水平的改變情況,明確電針對圍絕經(jīng)期相關(guān)癥狀的治療效應(yīng)和頻次的關(guān)系,初步探討電針不同頻次對圍絕經(jīng)期患者性激素水平的影響。2方法將符合本研究納入、排除標(biāo)準(zhǔn)的患者30例按照1:1比例隨機(jī)分為研究組和對照組,病例主要來源于安徽中醫(yī)藥大學(xué)第一附屬醫(yī)院針灸科、婦科門診和安徽中醫(yī)藥大學(xué)國醫(yī)堂門診部針灸科。研究組和對照組采用相同的治療操作方法和療程,但研究組治療頻次為一周三次,對照組為一周一次。兩組操作方法及療程為:取穴關(guān)元、子宮雙、天樞雙、三陰交雙,針刺后,雙側(cè)子宮和雙側(cè)天樞穴針柄分別橫向連接電針儀導(dǎo)線(電針參數(shù):疏密波,頻率為10/50Hz,電流強(qiáng)度為0.5~1.0 m A),逐漸增大電流強(qiáng)度以患者腹部輕微顫動為度,留針30分鐘,留針期間關(guān)元和三陰交穴行針3次,每10分鐘1次;共治療8周。兩組均隨訪至32周結(jié)束。兩組均在第0周、第4周、第8周、第20周和第32周5個時間點(diǎn)采用MRS量表對患者的癥狀進(jìn)行評價,并在第0周、第8周和第20周3個時間點(diǎn)檢測性激素。運(yùn)用統(tǒng)計軟件SPSS19.0進(jìn)行統(tǒng)計分析,所有檢驗采用雙側(cè)檢驗,P0.05被認(rèn)為具有統(tǒng)計學(xué)意義。3結(jié)果(1)研究組患者在治療后第4周、第8周、第20周和第32周的MRS評分均有明顯降低,差異具有顯著性統(tǒng)計學(xué)意義(P0.01);對照組患者第4周、第8周的MRS評分有明顯降低,差異有顯著性統(tǒng)計學(xué)意義(P0.01),在第20周時MRS評分的降低差異有統(tǒng)計學(xué)意義(P0.05),第32周的MRS評分與基線期相比,差異無統(tǒng)計學(xué)意義(P0.05);治療后兩組第4周、第8周、第20周組間比較差異無統(tǒng)計學(xué)意義(P0.05),第32周組間比較差異有顯著性統(tǒng)計學(xué)意義(P0.01)。(2)患者的FSH、LH、E2水平組內(nèi)和組間比較差異均無統(tǒng)計學(xué)意義(P0.05)。(3)治療8周后,研究組的總有效率為85.7%,對照組的總有效率為69.2%,兩者比較差異無統(tǒng)計學(xué)意義(P0.05);治療后第32周,研究組的總有效率為100%,對照組的總有效率為38%,兩者比較差異有顯著性統(tǒng)計學(xué)意義(P0.01);。4結(jié)論(1)電針能夠有效緩解圍絕經(jīng)期相關(guān)癥狀,是臨床治療圍絕經(jīng)期綜合征的有效方法。(2)針對圍絕經(jīng)期相關(guān)癥狀的電針治療,一周三次和一周一次的治療頻次所產(chǎn)生的近期療效無明顯差異;一周三次的遠(yuǎn)期療效優(yōu)于一周一次。(3)電針對圍絕經(jīng)期綜合征患者性激素水平的調(diào)整作用不明顯。
[Abstract]:Objective to observe the changes of symptom score and sex hormone level in patients with peri-menopausal syndrome treated with electroacupuncture at different frequencies, and to clarify the relationship between the therapeutic effect and frequency of electroacupuncture on peri menopausal symptoms. Preliminary study on the effect of different frequency of electroacupuncture on sex hormone level in peri-menopausal patients. Methods 30 patients who met the criteria of exclusion were randomly divided into study group and control group according to the 1:1 ratio. The cases mainly come from the Department of Acupuncture and moxibustion of the first affiliated Hospital of Anhui University of traditional Chinese Medicine, the Department of Gynecology outpatient and the Department of Acupuncture and moxibustion of the outpatient Department of the The study group and the control group were treated with the same procedure and course of treatment, but the frequency of treatment was three times a week in the study group and once a week in the control group. The two groups of operation methods and course of treatment were as follows: acupoint Guan Yuan, uterus double, Sanyinjiao double, after acupuncture, bilateral uterus and bilateral Tianshu acupoint needle handle were transversely connected with electroacupuncture instrument wire (electroacupuncture parameter: density wave, electroacupuncture parameter: density wave), The frequency was 10 / 50 Hz, the current intensity was 0.5 ~ (1. 0) Ma ~ (-1), and the current intensity was gradually increased to the degree of slight fibrillation in the abdomen of the patient. The needle was kept for 30 minutes. During the period of keeping the needle, the points of Guan Yuan and Sanyinjiao were needled 3 times every 10 minutes, and the total treatment was 8 weeks. Both groups were followed up to the end of 32 weeks. The symptoms of the patients were evaluated by Mrs at 5 time points (0 week, 4 week, 8 week, 20 week and 32 week), and sex hormones were measured at 0, 8 and 20 weeks. Statistical software SPSS 19.0 was used to carry out statistical analysis. All the tests were carried out with bilateral test (P0.05). The scores of Mrs were significantly decreased in the study group at the 4th, 8th, 20th and 32nd week after treatment. The difference was statistically significant (P 0.01), and the Mrs scores in the control group were significantly lower than those in the control group at the 4th week and the 8th week. The difference was statistically significant (P 0.01), and the decrease of Mrs score was statistically significant at the 20th week (P 0.05), but there was no significant difference between the 32 week and the baseline period (P 0.05), the fourth week, the eighth week after treatment, the difference between the two groups was not statistically significant (P 0.05), and there was no significant difference between the two groups at the 4th week and the 8th week after treatment. There was no significant difference between the two groups at the 20th week (P 0.05), but there was significant difference between the groups at week 32 (P 0.01). There was no significant difference in the level of FSHLHN E 2 in the group and between the two groups after 8 weeks of treatment, and there was no significant difference between the two groups after 8 weeks of treatment, there was no significant difference in the level of FSHLHN E2 between the two groups after 8 weeks of treatment, there was no significant difference between the two groups. The total effective rate was 85.7 in the study group and 69.2 in the control group. There was no significant difference between the two groups (P 0.05). The total effective rate of the study group was 100 and the total effective rate of the control group was 38. There was a significant difference between the two groups. It is an effective method for clinical treatment of peri-menopausal syndrome. (2) electroacupuncture treatment for peri-menopausal symptoms has no significant difference between the frequency of treatment three times a week and the frequency of treatment once a week. The long-term effect of three times a week is better than that of once a week.) the effect of electroacupuncture on sex hormone level in patients with perimenopausal syndrome is not obvious.
【學(xué)位授予單位】：安徽中醫(yī)藥大學(xué)
【學(xué)位級別】：碩士
【學(xué)位授予年份】：2016
【分類號】：R246.3

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