疏肝和胃抑酸降逆法治療非糜爛性胃食管反流病肝胃不和證的臨床觀察
發(fā)布時間:2018-06-08 07:20
本文選題:胃食管反流病 + 非糜爛性胃食管反流病 ; 參考:《黑龍江中醫(yī)藥大學》2017年碩士論文
【摘要】:目的:通過疏肝和胃抑酸降逆法治療非糜爛性胃食管反流病肝胃不和證的臨床觀察,評定其療效。方法:本研究在臨床上以治療前后自身對照的方法作為研究方法,對中醫(yī)辨證符合納入標準的46名非糜爛性胃食管反流病肝胃不和證患者進行治療,按患者就診的先后順序進行編號,予以基礎治療以及中藥疏肝和胃抑酸降逆法治療,治療時間為4周。觀察并記錄患者治療前后的中醫(yī)癥狀變化情況及胃食管反流病問卷積分情況。并于停藥后4周時,進行電話隨機訪問,填寫GerdQ問卷,利用癥狀積分統(tǒng)計復發(fā)情況。將所得數據結果錄入SPSS22.0軟件進行數據分析。結果:臨床治療過程中脫落患者2例,完成治療的患者共44例,療程結束后中醫(yī)證候療效統(tǒng)計結果為痊愈2例,占4.54%,顯效5例,占11.36%,有效35例,占79.54%,無效2例,占4.54%,中醫(yī)證候總有效率為95.45%。治療前與療程結束后中醫(yī)證候總積分(24.32±2.75,9.73±3.28),經統(tǒng)計學分析,Z=-5.78,P0.01,具有統(tǒng)計學意義。在單項證候積分方面,治療前后單項癥泛酸(5.32±1.05,1.86±1.00)、燒心(4.77±1.16,2.41±1.34)、胸骨后疼痛,牽及兩肋(4.05±1.46,1.77±1.08)、噯氣(4.36±1.16,1.82±0.95)、納差(1.48±0.88,0.45±0.50)、情緒不暢加重(1.57±0.73,0.52±0.59)、打呃(1.59±0.66,0.55±0.50)、惡心(1.18±0.58,0.34±0.48)病情程度比較,差異有統(tǒng)計學意義。治療前與治療后GerdQ問卷積分分別為14.55±1.90與7.32±1.30,經統(tǒng)計學分析Z=-5.79,P0.01。統(tǒng)計復發(fā)情況為44例中復發(fā)4例,復發(fā)率為9.09%。結論:1、疏肝和胃抑酸降逆法可有效改善非糜爛性胃食管反流病肝胃不和證患者的中醫(yī)癥狀。2、疏肝和胃抑酸降逆法可明顯降低非糜爛性胃食管反流病肝胃不和證患者的復發(fā)率。
[Abstract]:Objective: to evaluate the curative effect of the treatment of non-erosive gastroesophageal reflux disease with disharmony of liver and stomach. Methods: in this study, 46 patients with non-erosive gastroesophageal reflux syndrome were treated with self-control before and after treatment. The patients were treated with basic treatment and traditional Chinese medicine for 4 weeks. To observe and record the changes of TCM symptoms and the score of gastroesophageal reflux disease questionnaire before and after treatment. At 4 weeks after withdrawal, random telephone interview was conducted, GerdQ questionnaire was filled out, and recurrence was counted by symptom score. Input the data results into SPSS 2 2.0 software for data analysis. Results: in the course of clinical treatment, there were 2 cases of shedding patients and 44 cases of complete treatment. After the course of treatment, 2 cases were cured (4.54%), 5 cases were markedly effective, 11.36% were effective, 35 cases were effective, 79.54 cases were not effective, and 2 cases were ineffective. The total effective rate of TCM syndrome was 95.4545. The total score of TCM syndromes before treatment and after treatment was 24.32 鹵2.75 鹵9.73 鹵3.28, which was statistically significant by statistical analysis. 鍦ㄥ崟欏硅瘉鍊欑Н鍒嗘柟闈,
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