本文選題：圍絕經(jīng)期綜合征 + 圍絕經(jīng)期�。� 參考：《成都中醫(yī)藥大學(xué)》2016年碩士論文

【摘要】：目的：探討導(dǎo)師平衡腎陰腎陽法治療早期(圍絕經(jīng)期)圍絕經(jīng)期綜合征的用藥經(jīng)驗(yàn)并觀察其臨床療效,以期為中醫(yī)藥早期防治圍絕經(jīng)期綜合征提供客觀依據(jù)。方法：收集符合納入標(biāo)準(zhǔn)的圍絕經(jīng)期綜合征患者88例,給予平衡腎陰腎陽的中藥口服3個(gè)療程。分別于治療前后監(jiān)測(cè)血清卵泡刺激素(FSH)、黃體生成素(LH)、雌二醇(E2)水平,記錄改良Kupperman評(píng)分及中醫(yī)證候評(píng)分。采用自身前后對(duì)照的方法,判定療效,分析年齡、病程及病情與療效的相關(guān)性。結(jié)果：(1)觀察的88例患者中,根據(jù)改良Kupperman療效判定標(biāo)準(zhǔn),臨床治愈28例(31.82%),顯效54例(61.36%),有效6例(6.82%),無效0例,愈顯率達(dá)93.18%；根據(jù)中醫(yī)證候療效判定標(biāo)準(zhǔn),臨床痊愈31例(35.23%),顯效56例(63.63%),進(jìn)步1例(1.14%),無效0例,愈顯率達(dá)98.86%。(2)治療前后患者改良Kupperman積分、中醫(yī)證候積分經(jīng)統(tǒng)計(jì)分析P0.05,差異有統(tǒng)計(jì)學(xué)意義,表明平衡腎陰腎陽法可以顯著改善患者的臨床癥狀,減輕患者不適。(3)治療前后患者血清FSH、LH及E2水平經(jīng)統(tǒng)計(jì)分析P0.05,差異均有統(tǒng)計(jì)學(xué)意義,表明平衡腎臟陰陽法可以降低血清FSH、LH水平,提高血清E2水平。(4)患者年齡、病程、病情及用藥劑型與療效之間無相關(guān)性(P0.05)。(5)通過分析患者治療前后盆腔瘕瘕情況,發(fā)現(xiàn)平衡腎臟陰陽法并未增加盆腔ve瘕的相關(guān)風(fēng)險(xiǎn)。療程結(jié)束后對(duì)所有患者進(jìn)行血常規(guī)、凝血常規(guī)、肝腎功能檢查,皆未見異常。觀察期間所有患者皆未出現(xiàn)與藥物相關(guān)的不良反應(yīng),表明平衡腎臟陰陽法臨床運(yùn)用安全。結(jié)論：綜上,平衡腎陰腎陽法治療圍絕經(jīng)期PMS,可以顯著改善患者的臨床癥狀及血清相關(guān)性激素水平,并且不增加盆腔ve瘕的相關(guān)風(fēng)險(xiǎn),也未出現(xiàn)與藥物相關(guān)的不良反應(yīng),表明平衡腎陰腎陽法臨床運(yùn)用安全、有效。
[Abstract]:Objective: to explore the experience and clinical effect of tutor's method of balancing kidney yin and kidney yang in the treatment of peri-menopausal syndrome in order to provide an objective basis for early prevention and treatment of peri-menopausal syndrome by traditional Chinese medicine. Methods: 88 patients with perimenopausal syndrome who met the inclusion criteria were given three courses of oral administration of traditional Chinese medicine to balance kidney yin and kidney yang. The levels of serum follicle stimulating hormone (FSH), luteinizing hormone (LH), estradiol (E 2) were monitored before and after treatment, and the modified Kupperman score and TCM syndrome score were recorded. Self-control method was used to determine the curative effect and to analyze the correlation between age, course of disease and the curative effect. Results among 88 patients observed, 28 cases were cured according to modified Kupperman criteria, 54 cases were significantly effective, 6 cases were effective, 6.82 cases were ineffective, 0 cases were ineffective, and the effective rate was 93.18%, according to traditional Chinese medicine syndromes, 28 cases were cured and 31. 822%, 54 cases were effective, 6 cases were effective, 0 cases were ineffective, and the rate of recovery was 93.18%. There were 31 cases of clinical cure, 56 cases with remarkable effect and 63.63%, 1 case with improvement of 1.14%, 0 cases with no effect, and the effective rate reached 98.86%.) before and after treatment, the improved Kupperman integral was improved, and the score of TCM syndromes was statistically analyzed (P 0.05), the difference was statistically significant. The results showed that the method of balancing kidney yin and kidney yang could significantly improve the clinical symptoms and relieve the discomfort of the patients before and after treatment. The serum levels of FSHN LH and E2 were statistically significant by statistical analysis (P0.05). The results showed that the method of balancing kidney yin and yang could decrease the serum FSHN LH level and increase the serum E 2 level. There was no correlation between the age, course of disease, state of illness, dosage form and curative effect.) by analyzing the pelvic mass of the patients before and after treatment, there was no correlation between the patients' age, disease course, dosage form and curative effect. It was found that the method of balancing kidney yin and yang did not increase the risk of pelvic mass. After the course of treatment, all patients were examined with blood routine, coagulation, liver and kidney function. No adverse drug-related reactions were found in all patients during the observation period, indicating that the method of balancing kidney yin and yang was safe in clinical practice. Conclusion: in conclusion, the treatment of peri-menopausal PMSs with balanced kidney yin and kidney yang method can significantly improve the clinical symptoms and serum levels of sex hormones, and does not increase the risk of pelvic mass, and there are no adverse drug related reactions. It shows that the method of balancing kidney yin and kidney yang is safe and effective.
【學(xué)位授予單位】：成都中醫(yī)藥大學(xué)
【學(xué)位級(jí)別】：碩士
【學(xué)位授予年份】：2016
【分類號(hào)】：R249;R271.116

【參考文獻(xiàn)】

相關(guān)期刊論文 前10條

1 梁少琴;馮玉華;;姜坤教授治療圍絕經(jīng)期綜合征的經(jīng)驗(yàn)介紹[J];光明中醫(yī);2015年03期

2 彭曉華;吳聯(lián)專;;心理護(hù)理干預(yù)管理對(duì)圍絕經(jīng)期綜合征患者心理狀態(tài)的影響[J];中醫(yī)藥管理雜志;2015年05期

3 任紅娟;楊睿;;坤泰膠囊對(duì)比雌孕激素序貫療法治療圍絕經(jīng)期綜合征的臨床療效及對(duì)生存質(zhì)量的影響[J];中國生化藥物雜志;2015年02期

4 陳繼明;高紅艷;李沁;;坤泰膠囊治療圍絕經(jīng)期綜合征患者30例臨床觀察[J];中醫(yī)雜志;2015年03期

5 程芙蓉;王雯;;坤泰膠囊對(duì)圍絕經(jīng)期綜合征患者雌激素及其受體表達(dá)的影響[J];中華中醫(yī)藥學(xué)刊;2014年09期

6 段燕康;李芳;李進(jìn)東;魏茂陳;;坤泰膠囊對(duì)更年期雌鼠激素水平及圍絕經(jīng)期綜合征的影響[J];中國醫(yī)院藥學(xué)雜志;2014年06期

7 韓玉環(huán);劉冰;邵穎;賈東輝;;圍絕經(jīng)期綜合征中醫(yī)病因病機(jī)特點(diǎn)探討[J];中國醫(yī)藥指南;2013年13期

8 徐哲;謝萍;鄭靜;馮飛;馬艷;蔚秀敏;;淺談圍絕經(jīng)期綜合征的病因病機(jī)與治則[J];湖南中醫(yī)雜志;2013年03期

9 馬新想;張富青;;坤泰膠囊在卵巢早衰患者中的臨床應(yīng)用分析[J];中國醫(yī)學(xué)工程;2012年12期

10 李莉;;心理治療和健康教育在治療女性更年期綜合征中療效觀察[J];當(dāng)代醫(yī)學(xué);2012年18期

相關(guān)會(huì)議論文 前1條

1 吳克明;付雨;徐曉娟;仝崇毅;;通脈大生片對(duì)卵巢功能低下大鼠卵巢激素與血供的影響[A];第十次全國中醫(yī)婦科學(xué)術(shù)大會(huì)論文集[C];2010年

相關(guān)碩士學(xué)位論文 前1條

1 張琳慧;圍絕經(jīng)期綜合征的文獻(xiàn)研究[D];北京中醫(yī)藥大學(xué);2007年

，

本文編號(hào)：1968675