本文選題：慢性乙型肝炎 + 中藥治療��； 參考：《山東中醫(yī)藥大學(xué)》2016年碩士論文

【摘要】：目的:初步探討慢性乙型肝炎證型分布特點(diǎn),總結(jié)導(dǎo)師治療本病用藥規(guī)律,為中醫(yī)藥治療慢性乙型肝炎提供理論基礎(chǔ)和實(shí)踐依據(jù)。方法:本課題采用病例回顧性分析的方法,借助中醫(yī)臨床信息采集系統(tǒng)記錄171例經(jīng)治有效的慢性乙型肝炎患者的臨床一般資料和處方用藥,運(yùn)用數(shù)據(jù)挖掘技術(shù)結(jié)合統(tǒng)計(jì)學(xué)進(jìn)行處理,總結(jié)導(dǎo)師臨床用藥規(guī)律,并加以總結(jié)。結(jié)果:1.本次研究中,171例慢性乙型肝炎患者中男性118例,女性53例;2.本次研究中統(tǒng)計(jì)到中醫(yī)證型6種,按頻數(shù)大小排序?yàn)楦斡羝⑻撔透文憹駸嵝透文I陰虛型瘀血阻絡(luò)型脾腎陽虛型肝郁氣滯型,總體對(duì)比P0.05,有統(tǒng)計(jì)學(xué)意義;3.慢性乙型肝炎性別、年齡總體比較P0.05,有顯著差異;4.導(dǎo)師臨床用藥規(guī)律:(1)肝膽濕熱型:第一類主藥為茵陳、敗醬草、蘆根、竹葉、黃連、黃芩,第二類為柴胡、陳皮,第三類為雞內(nèi)金、山藥、薏苡仁、豆蔻,第四類為浙貝母、生牡蠣。(2)肝郁脾虛型:第一類主藥為黃芪、薏苡仁、雞內(nèi)金、山藥,第二類為郁金、陳皮,第三類為茵陳、敗醬草、板藍(lán)根、蘆根,第四類為當(dāng)歸、川芎、牛膝、白芍。(3)肝腎陰虛型:第一類主藥為枸杞、女貞子、旱蓮草、生地黃、杜仲,第二類為雞內(nèi)金、山藥、薏苡仁,第三類為茵陳、敗醬草、板藍(lán)根、竹葉、蘆根,第四類為柴胡、郁金,第五類為當(dāng)歸、莪術(shù)。(4)瘀血阻絡(luò)型:第一類主藥為當(dāng)歸、赤芍、川芎,第二類為柴胡、枳殼、桔梗、郁金,第三類為生牡蠣、莪術(shù)、浙貝母,第四類為牛膝、生地黃、白芍,第五類為黃芪、雞內(nèi)金、山藥、薏苡仁,第六類為茵陳、敗醬草、板藍(lán)根。(5)脾腎陽虛型:第一類主藥為附子、桂枝;第二類熟地黃、女貞子、枸杞、山萸肉,第三類為黃芪、薏苡仁、山藥、雞內(nèi)金,第四類茯苓、白術(shù),第五類茵陳、敗醬草、車前草。(6)肝郁氣滯型:第一類主藥為柴胡、佛手、香附、枳殼、川芎、郁金,第二類主藥為雞內(nèi)金、茯苓、枳實(shí),第三類茵陳、敗醬草、板藍(lán)根、蘆根、竹葉,第四類生牡蠣、浙貝母。結(jié)論:1.運(yùn)用中醫(yī)臨床信息采集系統(tǒng)可以將大量的信息(如患者的臨床資料和處方用藥)加以匯總,形成自己獨(dú)立的數(shù)據(jù)庫,方便查找,避免了數(shù)據(jù)的丟失,亦使得數(shù)據(jù)變的更加客觀、真實(shí);2.數(shù)據(jù)挖掘是總結(jié)、傳承中醫(yī)經(jīng)驗(yàn)的有效途徑:數(shù)據(jù)挖掘技術(shù)可以使導(dǎo)師的經(jīng)驗(yàn)變的更直觀、更易懂,同時(shí)還可以進(jìn)行重復(fù)性的操作,這對(duì)中醫(yī)學(xué)學(xué)術(shù)經(jīng)驗(yàn)的繼承以及中醫(yī)學(xué)的發(fā)展創(chuàng)新有著極其重要的意義;3.運(yùn)用數(shù)據(jù)挖掘技術(shù)分析海量的中醫(yī)診療信息,有助于發(fā)現(xiàn)中醫(yī)辨證施治、處方用藥等環(huán)節(jié)中隱含的關(guān)鍵關(guān)聯(lián)和規(guī)律,使得最后得出的結(jié)果更具客觀真實(shí)性,更好的為中醫(yī)藥治療慢性乙型肝炎提供理論基礎(chǔ)和實(shí)踐依據(jù)。4.中醫(yī)臨床信息采集系統(tǒng)和數(shù)據(jù)挖掘技術(shù)為中醫(yī)對(duì)慢性乙型肝炎的研究提供了新平臺(tái),節(jié)約了勞動(dòng)力,減小了誤差,對(duì)中醫(yī)學(xué)術(shù)水平的提高有著重大的作用。5.整理總結(jié)導(dǎo)師治療慢性乙型肝炎的經(jīng)驗(yàn)。導(dǎo)師認(rèn)為肝郁脾虛是慢乙肝的主要病機(jī)之一,調(diào)肝健脾法貫穿于慢乙肝治療始終;疾病后期,應(yīng)注重補(bǔ)腎養(yǎng)肝;針對(duì)病因,勿忘清熱利濕解毒。
[Abstract]:Objective: to preliminarily discuss the distribution characteristics of the syndrome type of chronic hepatitis B, summarize the rule of medication for the treatment of this disease, and provide the theoretical basis and practical basis for the treatment of chronic hepatitis B with Chinese medicine. Methods: this subject uses a retrospective analysis of cases and records 171 cases of chronic hepatitis B with the help of clinical information collection system of traditional Chinese medicine. The clinical general data and prescription drug use, data mining technique combined with statistics to summarize the rule of clinical medication of the tutor and summarize. Results: in 1. studies, 171 cases of chronic hepatitis B patients were 118 cases and 53 women, and 6 of the 2. studies were statistically classified as liver depression according to frequency. Spleen deficiency type liver and gallbladder damp heat type liver kidney yin deficiency type spleen kidney yang deficiency type liver qi stagnation type, overall comparison P0.05, has statistical significance; 3. chronic hepatitis B sex, age overall comparison P0.05, significant difference; (1) the liver and gallbladder damp heat type: the first type of main medicine is Artemisia, Rhizoma Patrinia, reed root, bamboo leaf, Huanglian, Scutellaria, The second category is Bupleurum bupleurum, tangerine peel, third types of chicken inner gold, yam, coix seed, nutmeg, fourth kinds of Zhejiang Fritillaria, raw oysters. (2) liver qi stagnation and spleen deficiency type: the first class main medicine is Astragalus membranaceus, coix seed, chicken inner gold, yam, the second kinds are the tulips, the third types are Yin Chen, the rhizoma Patrinia, the Radix Isatis Root, the root, the root, and the fourth types are angelica, Ligusticum chuanxiong, Achyranthes and paeony. (3) liver kidney yin Virtual type: the first type of main medicine is Lycium barbarum, Ligustrum lucidum, Rhizoma rehmanniae, Eucommia ulmoides, the second types are chicken inner gold, yam, coix seed, third kinds of Artemisia, Rhizoma Patrinia, Radix Isatidis, bamboo leaves, Ruta root, fourth types of Chaihu, tulip, fifth types of angelica, zedoary turmeric. (4) the main drug is angelica, Radix Paeoniae, chuanxiong, the second kinds of bupleurum, Fructus aurantii, Fructus aurantii, Platycodon grandiflorum, tulip, third types of oyster, zedoary turmeric, Fritillaria thunbergii, fourth kinds of Achyranthes, rehmannia, Paeonia lactiflora, fifth kinds of Astragalus, cinnamon, yam, coix seed, sixth types of Yin Chen, Patrinia, isatis root. (5) spleen and kidney yang deficiency: the first class main medicine is the Radix Aconiti, Cinnamomum, second types of cooked ground yellow, Ligustrum lucidum, Lycium barbarum, coix seed, and the third classes of Astragalus, coix seed, coix seed, and the third category of Coix seed Coix kernel Yam, chicken inner gold, fourth kinds of Poria cocos, Atractylodes macrocephala, fifth kinds of Artemisia, Patrinia, Plantago. (6) stagnation of liver Qi: the first major drugs are Radix Bupleuri, fingered, Fructus trifoliate, chuanxiong, tulip, and the second kinds of main drugs are chicken inner gold, Poria cocos, Fructus aurantii, Radix Isatidis, Radix Isatis, bamboo leaves, fourth kinds of raw oysters and Fritillaria thunbergii. Conclusion: 1. use traditional Chinese medicine (1.). Conclusion: 1. use traditional Chinese medicine. The clinical information collection system can collect a large amount of information (such as patients' clinical data and prescription drugs), form their own independent database, facilitate the search, avoid the loss of data, and make the data more objective and true. 2. data mining is an effective way to sum up and inherit the experience of traditional Chinese medicine: data mining technology can make The experience of the tutor is more intuitionistic, more easy to understand, and can also be repeated, which is of great significance to the inheritance of the academic experience of traditional Chinese medicine and the development and innovation of traditional Chinese medicine. 3. the application of data mining technology to the analysis of massive Chinese medical diagnosis and treatment information will help to find the link of TCM syndrome differentiation and prescription medication. The key correlation and rules make the final results more objective and realistic, and provide a theoretical basis and practical basis for the treatment of chronic hepatitis B by traditional Chinese medicine. The.4. clinical information collection system and data mining technology provide a new platform for the study of chronic hepatitis B, saving the labor force and reducing the error. The improvement of the academic level of Chinese medicine has a great effect on the experience of the treatment of chronic hepatitis B by.5.. The tutor thinks that the liver depression and spleen deficiency is one of the main pathogenesis of the chronic hepatitis B. The method of regulating the liver and invigorating the spleen throughout the treatment of the chronic hepatitis B; the later period of the disease should pay attention to the nourishing the kidney and nourishing the liver; for the cause of the disease, you should not forget to clear the heat, wet the detoxification of the dampness and the dampness.
【學(xué)位授予單位】：山東中醫(yī)藥大學(xué)
【學(xué)位級(jí)別】：碩士
【學(xué)位授予年份】：2016
【分類號(hào)】：R249;R259

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