本文選題：針灸 + 頑固性呃逆��； 參考：《成都中醫(yī)藥大學(xué)》2016年碩士論文

【摘要】：目的通過Meta分析方法,評價針灸治療頑固性呃逆的臨床療效與安全性。方法采用計算機檢索檢索為主、手工檢索為輔的方式,以針灸、針刺、艾灸、頑固性呃逆等12個中文詞語和16個英文詞語為關(guān)鍵詞或主題詞,區(qū)分綜合性數(shù)據(jù)庫、會議論文數(shù)據(jù)庫和學(xué)位論文數(shù)據(jù)庫3類13個數(shù)據(jù)庫,設(shè)置檢索時間為2005年至2015年12月30日,全面檢索針灸治療頑固性呃逆相關(guān)研究。按照文獻納入與排除標(biāo)準,確定納入符合標(biāo)準文獻,提取文獻特征,并采用Jadad評分法進行質(zhì)量評價。最后采用定量分析與定性分析結(jié)合的方式,對所納入研究的臨床對照試驗進行Meta分析,評價針灸治療頑固性呃逆的臨床療效與安全性。結(jié)果本文共納入52篇隨機對照試驗,根據(jù)治療組干預(yù)措施的不同區(qū)分5個組進行Meta分析。其中針灸聯(lián)合常規(guī)治療對照常規(guī)治療組納入8篇文獻(681例患者),針灸對照西藥組納入19篇文獻(1221例患者),針灸對照針灸組納入11篇文獻(1022)例患者,針灸聯(lián)合中藥對照單純中藥或西藥治療組納入7篇文獻(493例患者),針灸聯(lián)合西藥對照針灸或西藥組納入7篇文獻(480例患者)。所有文獻均采用“隨機”分組,20篇文獻描述了具體分組方法；2篇文獻使用盲法,但具體實施措施未予以描述；1篇文獻進行了樣本量估算,但未描述具體估算方法；46篇文獻描述基線情況；4篇文獻提及脫落與退出,未詳細描述具體情況；5篇文獻描述不良反應(yīng),僅1篇描述具體信息；13篇文獻提及隨訪情況,僅1篇文獻描述具體信息；所有文獻均未進行ITT分析。整體文獻質(zhì)量較低。Meta分析結(jié)果顯示：針灸聯(lián)合常規(guī)治療、針刺聯(lián)合灸法、針灸聯(lián)合中藥、穴位注射聯(lián)合耳穴、耳針等治療頑固性呃逆具有一定效果,優(yōu)于西藥治療頑固性呃逆。尚不能證明電針、針灸配合西藥治療頑固性呃逆療效。結(jié)論目前國內(nèi)研究針灸治療頑固性呃逆的文獻數(shù)量比較龐大,質(zhì)量多處于中等偏低水平。針灸聯(lián)合常規(guī)治療、針刺聯(lián)合灸法、針灸聯(lián)合中藥、穴位注射聯(lián)合耳穴、耳針等治療頑固性呃逆具有一定效果,能夠有效緩解或消除呃逆癥狀。尚不能證明電針、針灸配合西藥治療頑固性呃逆療效。由于缺乏不良反應(yīng)數(shù)據(jù),無法對針灸治療頑固性呃逆安全性作出客觀評價。
[Abstract]:Objective to evaluate the clinical efficacy and safety of acupuncture and moxibustion in the treatment of intractable hiccup by Meta analysis. Methods 12 Chinese words and 16 English words, such as acupuncture, moxibustion and obstinate hiccup were used as key words or subject words. There were 13 databases of conference papers database and degree thesis database with retrieval time from 2005 to December 30, 2015. The related research on acupuncture and moxibustion treatment of intractable hiccup was comprehensively searched. According to the criteria of literature inclusion and exclusion, the inclusion of standard documents was determined, the characteristics of documents were extracted, and the quality evaluation was carried out by Jadad scoring method. Finally, the clinical efficacy and safety of acupuncture and moxibustion for intractable hiccup were evaluated by Meta analysis. Results A total of 52 randomized controlled trials were included and Meta analysis was performed in 5 groups according to different intervention measures in the treatment group. Among them, the acupuncture and moxibustion combined with conventional therapy and conventional therapy group included 8 literatures (681 patients), the acupuncture and moxibustion control western medicine group included 19 literatures (1221 patients), the acupuncture control group included 11 literatures (1022), and the acupuncture and moxibustion control group (Acupuncture and moxibustion control group) included 11 articles (1022). 493 patients were treated with acupuncture and moxibustion combined with traditional Chinese medicine alone or western medicine, and 480 patients were treated with acupuncture combined with western medicine or western medicine. All the literatures used "random" grouping of 20 articles to describe the specific grouping method and 2 articles using blind method, but the practical measures were not described and 1 document was used to estimate the sample size. However, no specific estimation methods were described in 46 articles describing the baseline situation, 4 references to abscission and withdrawal, 5 cases to adverse reactions described in detail, only 1 article describing specific information and 13 references to follow-up, and 4 references to abscission and withdrawal, only 1 description of specific information and 13 references to follow-up. Only one document described the specific information; none of the literature was analyzed by ITT. The results showed that acupuncture combined with routine therapy, acupuncture combined with moxibustion, acupuncture combined with traditional Chinese medicine, acupoint injection combined with ear points, ear acupuncture and so on, had certain effect in the treatment of intractable hiccup, which was superior to western medicine in the treatment of obstinate hiccup. It is not possible to prove the curative effect of electroacupuncture, acupuncture and western medicine on intractable hiccup. Conclusion the literature on acupuncture and moxibustion in treating obstinate hiccup is large in quantity and low in quality. Acupuncture combined with routine treatment, acupuncture combined with moxibustion, acupuncture combined with traditional Chinese medicine, acupoint injection combined with ear points, ear acupuncture treatment of intractable hiccup has a certain effect, can effectively alleviate or eliminate hiccup symptoms. It is not possible to prove the curative effect of electroacupuncture, acupuncture and western medicine on intractable hiccup. The safety of acupuncture and moxibustion for intractable hiccup can not be evaluated objectively due to the lack of adverse reaction data.
【學(xué)位授予單位】：成都中醫(yī)藥大學(xué)
【學(xué)位級別】：碩士
【學(xué)位授予年份】：2016
【分類號】：R246.1

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本文編號：1930909