丹參注射液穴位注射配合走罐治療尋常型痤瘡的臨床研究
發(fā)布時間:2018-05-24 06:46
本文選題:尋常型痤瘡 + 穴位注射 ; 參考:《廣西中醫(yī)藥大學》2016年碩士論文
【摘要】:目的:本研究通過對丹參注射液穴位注射配合走罐與口服異維A酸軟膠囊(泰爾絲)聯(lián)合外涂0.025%維A酸乳膏兩者治療尋常型痤瘡的臨床療效進行對比,科學客觀地評價丹參注射液穴位注射配合走罐治療尋常型痤瘡的臨床療效及安全性,為其在臨床實踐中的推廣而提供較為客觀的依據(jù)。方法:將符合本課題納入標準的60例尋常型痤瘡患者,隨機地分成兩組,治療組收集30例,采用丹參注射液穴位注射配合走罐治療,每3天進行丹參注射液穴位注射配合走罐1次,7次為1個療程;藥物對照組收集30例,口服異維A酸軟膠囊(泰爾絲),每次10mg,1次/天,晚上外涂0.025%維A酸乳膏,3周為1個療程。治療兩個療程后進行治療前后皮損總數(shù)目、皮損分級對比,觀察兩組臨床療效。結果:通過分析臨床研究及統(tǒng)計學數(shù)據(jù):臨床療效方面,治療組共30例,痊愈20例,顯效6例,有效3例,無效1例,總有效率為86.67%;藥物對照組共30例,痊愈12例,顯效7例,有效6例,無效6例,總有效率為63.33%,經(jīng)檢驗P0.05,治療組優(yōu)于藥物對照組,差異有統(tǒng)計學的意義;經(jīng)過治療后患者皮損數(shù)目兩組間的差異有統(tǒng)計學意義P0.05;兩組治療組未痊愈患者皮損嚴重程度的分級:Ⅰ級的患者有5例,Ⅱ級的患者有4例,Ⅲ級的患者有1例;而對照組的患者中:Ⅰ級的患者有7例,Ⅱ級的患者有7例,Ⅲ級的患者有4例,經(jīng)檢驗P0.05,差異具有統(tǒng)計學意義。治療一個月后,臨床療效方面,30例治療組患者痊愈有5例,顯效16例,有效5例,無效4例,總體的有效率為70.00%;30例對照組患者中痊愈2例,顯效8例,有效10例,無效10例,總體的有效率為33.33%,經(jīng)檢驗P0.05,差異具有統(tǒng)計學意義;比較兩組患者療程結束后隨訪的復發(fā)率,治療組的20例痊愈患者中有1例復發(fā)患者,復發(fā)率為5.00%;對照組中的12例痊愈患者有2例復發(fā),復發(fā)率為16.67%;說明了丹參注射液穴位注射配合走罐的治療方法遠期的療效也令人滿意。結論:(1)丹參注射液穴位注射配合走罐療法治療尋常型痤瘡除了有較好的近期療效之外,還有著令人較為滿意的遠期療效。(2)丹參注射液穴位注射配合走罐療法能夠清肺解毒,涼血活血,調理沖任,不僅改善患者的顏面部皮膚,還從整體上調節(jié)患者血液循環(huán),提高患者機體的免疫能力,其綜合療效明顯優(yōu)于異維A酸軟膠囊(泰爾絲)聯(lián)合0.025%維A酸乳膏的治療。(3)治療組在治療過程中沒有出現(xiàn)明顯的不良反應,藥物對照組部分患者有口唇干裂、皮膚灼熱、紅斑、脫屑等不良反應,說明丹參注射液穴位注射配合走罐療法比較常規(guī)西藥治療尋常型痤瘡更加安全可靠。
[Abstract]:Objective: to compare the clinical efficacy of salvia miltiorrhiza injection combined with walking cupping and oral isotinic acid soft capsule (Tilsi) combined with 0.025% retinoic acid cream in the treatment of acne vulgaris. To evaluate scientifically and objectively the clinical efficacy and safety of salvia miltiorrhiza injection combined with cupping in the treatment of acne vulgaris, and to provide a more objective basis for its popularization in clinical practice. Methods: sixty patients with acne vulgaris were randomly divided into two groups. 30 patients in the treatment group were treated with acupoint injection of Salvia miltiorrhiza and cupping. Every 3 days, salvia miltiorrhiza injection acupoint injection combined with cupping for 7 times was used as a course of treatment, and 30 patients in the control group were treated with isotinic acid soft capsules (10 mg / day, 10 mg / day), and 0.025% retinoic acid cream was applied outside for 3 weeks as a course of treatment in the drug control group. After two courses of treatment, the total number of skin lesions and the grading of lesions were compared before and after treatment, and the clinical efficacy of the two groups was observed. Results: through the analysis of clinical research and statistical data: there were 30 cases in the treatment group, 20 cases were cured, 6 cases were effective, 3 cases were effective, 1 case was ineffective, the total effective rate was 86.67%, 30 cases were in the drug control group, 12 cases were cured, 7 cases were remarkable effect. There were 6 cases of effective and 6 cases of ineffective, the total effective rate was 63.33. The treatment group was better than the drug control group after testing (P0.05), the difference was statistically significant. After treatment, there was a significant difference in the number of skin lesions between the two groups (P 0.05). There were 5 cases of grade 鈪,
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