本文選題：更年期綜合征 + 潮熱��； 參考：《成都中醫(yī)藥大學(xué)》2016年碩士論文

【摘要】：目的：本研究通過(guò)探索更年期潮熱發(fā)作及加重的時(shí)間節(jié)律性,分析其與更年期綜合征中醫(yī)證型之間的相關(guān)性,以期從時(shí)間節(jié)律的角度為更年期潮熱患者的中醫(yī)診療提供一種辨證思路,以及為擇時(shí)給藥的臨床應(yīng)用提供理論參考依據(jù)。方法：通過(guò)查閱相關(guān)文獻(xiàn)及臨床觀察,參照導(dǎo)師經(jīng)驗(yàn)及專家意見(jiàn)設(shè)計(jì)調(diào)查表,共設(shè)定7個(gè)時(shí)間項(xiàng)目,分別為不定時(shí)項(xiàng)、全夜項(xiàng)、全日項(xiàng)、前半夜、后半夜、上半日、下半日,收集2015年2月-2016年2月符合本試驗(yàn)納入標(biāo)準(zhǔn)的患者共369例,使用EXCEL表建立信息數(shù)據(jù)庫(kù),運(yùn)用SPSS 17.0統(tǒng)計(jì)軟件包,對(duì)數(shù)據(jù)進(jìn)行頻數(shù)分析、聚類分析、卡方檢驗(yàn)等,最后得出結(jié)論。結(jié)果：(1)本研究共納入更年期潮熱患者369例,潮熱發(fā)作及加重有定時(shí)者共314例,占總百分比的85%,無(wú)定時(shí)者共55例,占總百分比的15%,差異有統(tǒng)計(jì)學(xué)意義(p0.05)；(2)對(duì)369例患者的中醫(yī)癥候進(jìn)行統(tǒng)計(jì)學(xué)聚類分析,總結(jié)出七個(gè)更年期綜合征的中醫(yī)證型,分別是腎陰虛證84例,腎陽(yáng)虛證43例,腎陰陽(yáng)俱虛證48例,心腎不交證47例,腎虛血瘀證40例,陰虛肝旺證58例,肝郁血熱證49例。(3)潮熱發(fā)作及加重于夜間者共73例,以腎陰虛證最多見(jiàn),共計(jì)42例；潮熱發(fā)作及加重于白天者共53例,以肝郁血熱證最多見(jiàn),共計(jì)19例：潮熱發(fā)作及加重于上半日共37例,以腎陽(yáng)虛證最多見(jiàn),共計(jì)14例；潮熱發(fā)作及加重于下半日者53例,以心腎不交證最多見(jiàn),共計(jì)18例；潮熱發(fā)作及加重于前半夜者共56例,以腎虛血瘀證最多見(jiàn),共計(jì)19例；潮熱發(fā)作及加重于后半夜者共42例,以陰虛肝旺證最多見(jiàn),共計(jì)18例；各時(shí)間組中醫(yī)證型構(gòu)成比比較,差異均有統(tǒng)計(jì)學(xué)意義(p0.01)；(4)腎陰虛證更年期綜合征患者共84例,潮熱發(fā)作及加重于夜間者最多見(jiàn),共計(jì)42例；腎陽(yáng)虛證更年期綜合征患者共43例,潮熱發(fā)作及加重于上半日者最多見(jiàn),共計(jì)14例；心腎不交證更年期綜合征患者共47例,潮熱發(fā)作及加重于下半日者最多見(jiàn),共計(jì)18例；腎虛血瘀證更年期綜合征患者共40例,潮熱發(fā)作及加重于前半夜者最多見(jiàn),共計(jì)19例；陰虛肝旺證更年期綜合征患者共58例,潮熱發(fā)作及加重于后半夜者多見(jiàn),共計(jì)18例；肝郁血熱證更年期綜合征患者共49例,潮熱發(fā)作及加重于白天者最多見(jiàn),共計(jì)19例；各中醫(yī)證型組潮熱發(fā)作及加重時(shí)間構(gòu)成比比較,差異均有統(tǒng)計(jì)學(xué)意義(p0.05)。結(jié)論：更年期潮熱發(fā)作及加重具有時(shí)間節(jié)律性,更年期潮熱發(fā)作及加重的時(shí)間與更年期綜合征中醫(yī)證型相關(guān)。
[Abstract]:Objective: to explore the temporal rhythm of climacteric hot flashes and to analyze its correlation with the TCM syndromes of climacteric syndrome. In order to provide a dialectical thinking for the diagnosis and treatment of climacteric hot flashes from the point of view of time rhythm, as well as to provide a theoretical reference for the clinical application of drug timing. Methods: according to the related literature and clinical observation, the questionnaire was designed according to the tutor's experience and expert's opinion. Seven time items were set up, which were unscheduled item, whole night item, whole day item, the first midnight, the later midnight, the first half, the second half of the day, the first half of the night, the second half of the day. From February 2015 to February 2016, 369 patients who met the criteria of this experiment were collected. The information database was established by using EXCEL table, and the frequency analysis, cluster analysis and chi-square test were carried out by using SPSS 17.0 statistical software package. Finally, the conclusion was drawn. Results (1) in this study, 369 climacteric hot flashes were included. There were 314 cases with regular onset and exacerbation of hot flashes, accounting for 85% of the total, and 55 cases without timing. 15% of the total, the difference was statistically significant (p 0.05) the TCM syndromes of 369 patients were analyzed statistically, and the seven TCM syndromes of climacteric syndrome were summed up. They were kidney yin deficiency syndrome 84 cases and kidney yang deficiency syndrome 43 cases. There were 48 cases of kidney yin and yang deficiency syndrome, 47 cases of heart and kidney disconnection syndrome, 40 cases of kidney deficiency and blood stasis syndrome, 58 cases of yin deficiency and liver flourishing syndrome, 49 cases of liver stagnation and blood heat syndrome. There were 53 cases of hot flashes and exacerbations during the day, the most common of which were liver depression and blood heat syndrome (19 cases), 37 cases of hot flashes and aggravation in the first half day, 14 cases of deficiency of kidney-yang syndrome, 53 cases of hot flashes attack and aggravation in the second half of the day. The most common cases were heart-kidney syndrome (18 cases), 56 cases of hot flashes and exacerbations in the first half of the night, 19 cases of kidney deficiency and blood stasis syndrome, 42 cases of hot flashes and aggravation in the late midnight, 18 cases of liver flourishing syndrome due to yin deficiency. There were 84 cases of climacteric syndrome of kidney yin deficiency syndrome, 42 cases of hot flashes and exacerbation at night, 43 cases of climacteric syndrome of deficiency of kidney-yang syndrome. The onset and aggravation of hot flashes occurred most frequently in the first half of the day, in a total of 14 cases; in 47 cases of climacteric syndrome of heart and kidney disconnection syndrome, 18 cases of hot flashes attack and aggravation in the second half of the day; and 40 cases of climacteric syndrome of deficiency of kidney and blood stasis syndrome, The onset and aggravation of hot flashes were most common in the first half of the night (19 cases in total), 58 cases in the climacteric syndrome of yin deficiency and liver hyperactivity syndrome, 18 cases in the hot flashes attack and aggravation in the late midnight, 49 cases in the climacteric syndrome of liver stagnation and blood heat syndrome, The onset and aggravation of hot flashes were most common in the daytime (19 cases), and there were significant differences in the proportion of the onset and exacerbation time of hot flashes in each TCM syndrome group (P 0.05). Conclusion: the onset and aggravation of menopausal hot flashes have temporal rhythm. The time of onset and aggravation of climacteric hot flashes is related to the TCM syndrome type of climacteric syndrome.
【學(xué)位授予單位】：成都中醫(yī)藥大學(xué)
【學(xué)位級(jí)別】：碩士
【學(xué)位授予年份】：2016
【分類號(hào)】：R271.116

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