益腎健脾化濁法治療腎性貧血的臨床療效觀察
本文選題:腎性貧血 + 益腎健脾化濁法; 參考:《黑龍江中醫(yī)藥大學(xué)》2017年碩士論文
【摘要】:目的:通過對益腎健脾化濁法治療腎性貧血的臨床觀察,評定并分析益腎健脾化濁法治療腎性貧血的臨床療效。方法:收集符合腎性貧血納入標(biāo)準(zhǔn)60例患者,隨機(jī)分成治療組和對照組,每組各30例,兩組患者均給予低鹽、低脂、優(yōu)質(zhì)低蛋白飲食,糖尿病患者給予糖尿病飲食;在控制血壓、血糖平穩(wěn)的情況下,對照組給予葉酸、鐵劑、rHu-EPO等常規(guī)對癥治療,治療組在對照組治療的基礎(chǔ)上加服益腎健脾化濁法方藥,療程為12周。評價(jià)兩組患者治療前后的療效及臨床癥狀改善情況,監(jiān)測治療前后的血紅蛋白(Hb),紅細(xì)胞壓積(HCT),紅細(xì)胞計(jì)數(shù)(RBC),血清鐵(SI),鐵蛋白(SF)以及肌酐、尿素氮的指標(biāo)。數(shù)據(jù)處理采用SPSS20.0統(tǒng)計(jì)學(xué)軟件進(jìn)行數(shù)據(jù)分析。結(jié)果:1.對照組總有效率為66.67%,治療組總有效率為86.67%,兩組療效比較具有統(tǒng)計(jì)學(xué)意義(P0.05),表明治療組優(yōu)于對照組;2.治療組和對照組在治療后Hb,Hct,RBC,SI,SF均較治療前升高,治療組優(yōu)于對照組,具有統(tǒng)計(jì)學(xué)意義(P0.05);3.治療組在降低肌酐、尿素氮,改善中醫(yī)證候積分方面優(yōu)于對照組,具有統(tǒng)計(jì)學(xué)意義(P0.05)。結(jié)論:1.益腎健脾化濁法治療腎性貧血,在改善腎性貧血的臨床癥狀和體征上優(yōu)于對照組;2.益腎健脾化濁法在提升血紅蛋白、紅細(xì)胞數(shù)目、紅細(xì)胞壓積、血清鐵及鐵蛋白的水平,降低尿素氮、血肌酐上,其作用優(yōu)于對照組。
[Abstract]:Objective: to evaluate and analyze the clinical effect of tonifying kidney and invigorating spleen and removing turbidity in the treatment of renal anemia. Methods: 60 patients with renal anemia were randomly divided into treatment group and control group with 30 patients in each group. The patients in both groups were given low salt, low fat, high quality and low protein diet, and diabetic patients were given diabetes diet. Under the condition of controlling blood pressure and stable blood sugar, the control group was treated with folic acid and iron agent rHu-EPO, and the treatment group was treated with tonifying kidney and strengthening spleen and removing turbid for 12 weeks. To evaluate the curative effect and clinical symptom improvement of the two groups before and after treatment, and to monitor the indexes of HB, HCT, RBCU, SFF, creatinine and urea nitrogen before and after treatment. SPSS20.0 statistical software was used to analyze the data. The result is 1: 1. The total effective rate of the control group was 66.67 and the total effective rate of the treatment group was 86.67. The comparison between the two groups showed that the treatment group was better than the control group (P 0.05). In the treatment group and the control group, the level of HBT HcttCnrRBC+ SISF was higher than that before treatment, and the treatment group was superior to the control group, which had statistical significance (P 0.05) and the control group was significantly higher than that in the control group (P < 0.05). The treatment group was superior to the control group in reducing creatinine, urea nitrogen and improving TCM syndromes score, which had statistical significance (P 0.05). Conclusion 1. The method of tonifying kidney and invigorating spleen and removing turbid in treating renal anemia is superior to control group in improving the clinical symptoms and signs of renal anemia. The method of tonifying kidney and strengthening spleen and removing turbid could improve the levels of hemoglobin, erythrocyte, hematocrit, serum iron and ferritin, reduce urea nitrogen and serum creatinine, and its effect was superior to that of the control group.
【學(xué)位授予單位】:黑龍江中醫(yī)藥大學(xué)
【學(xué)位級別】:碩士
【學(xué)位授予年份】:2017
【分類號】:R277.5
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