紫及生肌膏促進肛瘺術(shù)后創(chuàng)面愈合的臨床療效觀察
本文選題:紫及生肌膏 + 肛瘺術(shù)后。 參考:《福建中醫(yī)藥大學(xué)》2016年碩士論文
【摘要】:目的:對比紫及生肌膏紗條換藥與凡士林紗條換藥對肛瘺術(shù)后第10天辨證為虛證創(chuàng)面愈合的影響,主要通過觀察創(chuàng)面疼痛情況、創(chuàng)面分泌物情況、創(chuàng)面肉芽組織生長、創(chuàng)面面積等,探討紫及生肌膏紗條換藥對低位單純性肛瘺術(shù)后創(chuàng)面愈合影響的臨床療效。方法:將納入本實驗的研究對象60例患者,隨機分為治療組30例及對照組30例。治療組術(shù)后第2天予凡士林紗條換藥,術(shù)后第10天改予紫及生肌膏紗條換藥,對照組則單純予凡士林紗條換藥。受試者用藥前的一般情況(如性別、年齡、病程等)以及個體的局部癥狀及體征(如創(chuàng)面分泌物、疼痛情況、肉芽生長情況等)進行統(tǒng)計學(xué)比較,然后詳細(xì)記錄比較兩組在術(shù)后第13天(用藥后第3天)、術(shù)后第18天(用藥后8天)、術(shù)后第25天(用藥后第15天)創(chuàng)面分泌物、疼痛、肉芽組織的積分情況,計算術(shù)后第18天、術(shù)后第25天創(chuàng)面面積,術(shù)后第28天評價治療后總體療效。按照各評價指標(biāo),客觀記錄各評價得分,數(shù)據(jù)均采用統(tǒng)計學(xué)軟件SPSS18.0進行統(tǒng)計對比,得出統(tǒng)計結(jié)果,最終得出試驗結(jié)論。結(jié)果:本試驗共60例納入對象,完成60例,其中治療組、對照組各30例。實驗結(jié)果如下:(1)創(chuàng)面疼痛:兩組受試者在術(shù)后第13、18、25天創(chuàng)面疼痛進行統(tǒng)計學(xué)比較,差異‘有統(tǒng)計學(xué)意義(P0.05),說明治療組在用藥后第3天起改善疼痛情況明顯優(yōu)于對照組。(2)創(chuàng)面分泌物:兩組受試者在術(shù)后第13、18、25天創(chuàng)面分泌物分別比較,兩組差異有統(tǒng)計學(xué)意義(P0.05),說明治療組在用藥后第3天起改善分泌物情況明顯優(yōu)于對照組。(3)創(chuàng)面肉芽生長:兩組在術(shù)后第18、25天創(chuàng)面肉芽生長分布分別比較,兩組差異有統(tǒng)計學(xué)意義(P0.05),說明治療組在用藥后第8天起改善肉芽生長情況明顯優(yōu)于對照組。(4)創(chuàng)面面積:兩組術(shù)后第18、25天與用藥前進行組內(nèi)比較,均P0.05,差異均具有統(tǒng)計學(xué)意義,表明兩組在用藥后第8天起均有縮小創(chuàng)面面積的作用;兩組術(shù)后第18、25天進行組間比較,均P0.05,差異均具有統(tǒng)計學(xué)意義,說明治療組在縮小創(chuàng)面面積方面明顯優(yōu)于對照組。(5)創(chuàng)面愈合時間:兩組受試者創(chuàng)面愈合時間經(jīng)統(tǒng)計學(xué)比較,均P0.05,差異具有統(tǒng)計學(xué)意義,表明治療組在促進創(chuàng)面愈合方面明顯優(yōu)于對照組。(6)總療效:兩組術(shù)后第28天總療效比較,對照組創(chuàng)面治愈率為83.33%,治療組為100%,兩組創(chuàng)面28天總療效比較,經(jīng)統(tǒng)計分析(P0.05),差異有統(tǒng)計學(xué)意義,說明治療組在促進創(chuàng)面愈合方面明顯優(yōu)于對照組。(7)不良反應(yīng):兩組試驗過程中無不良反應(yīng)情況出現(xiàn)。結(jié)論:經(jīng)過分析本課題研究結(jié)果,可認(rèn)為肛瘺術(shù)后紫及生肌膏紗條換藥組的療效優(yōu)于凡士林紗條換藥組,主要體現(xiàn)在減少并改善創(chuàng)面分泌物、減輕創(chuàng)面疼痛情況、促進創(chuàng)面肉芽生長及創(chuàng)面愈合等方面。
[Abstract]:Objective: to compare the effect of dressing change between purple and Shengji ointment and vaseline gauze on wound healing of deficiency syndrome after 10 days of anal fistula, mainly by observing the condition of wound pain, the condition of wound secretion and the growth of wound granulation tissue. To investigate the effect of dressing change of purple and Shengji ointment on wound healing after low simple anal fistula. Methods: 60 patients were randomly divided into treatment group (n = 30) and control group (n = 30). In the treatment group, vaseline gauze was changed on the second day after operation, purple and Shengji ointment gauze was changed on the 10th day after operation, and the control group was treated with vaseline gauze only. The general conditions (such as sex, age, course of disease, etc.) and local symptoms and signs (such as wound discharge, pain, granulation growth, etc.) were compared statistically. Then the scores of wound secretion, pain and granulation tissue were recorded and compared in the two groups on the 13th day (3 days after medication), 18 days (8 days after medication), 25 days (15 days after medication), and 18 days after operation. The wound area was evaluated on the 25th day after operation and the overall curative effect was evaluated on the 28th day after operation. According to each evaluation index, objective record each evaluation score, the data all use the statistics software SPSS18.0 to carry on the statistical contrast, obtains the statistical result, finally obtains the test conclusion. Results: 60 cases were included in the experiment, including 30 cases in the treatment group and 30 cases in the control group. The results of the experiment were as follows: (1) wound pain: the two groups were statistically compared with each other on the 13th day, 1825 days after operation, The difference was statistically significant (P 0.05), which indicated that the treatment group was superior to the control group in improving the pain state from the 3rd day after treatment: the wound secretion of the two groups was compared on the 13th day, 1825 days after operation, respectively. The difference between the two groups was statistically significant (P 0.05), which indicated that the improvement of secretion in the treatment group was significantly better than that in the control group from the third day after treatment: the distribution of granulation growth in the two groups was compared on the 1825 day after operation. The difference between the two groups was statistically significant (P 0.05), which indicated that the improvement of granulation growth in the treatment group was significantly better than that in the control group from the 8th day after treatment. The wound area of the treatment group was significantly better than that of the control group (P 0.05). The results showed that the two groups had the effect of reducing the wound area from the 8th day after treatment, and the difference was statistically significant between the two groups on the 25th day after operation (P0.05). The results showed that the healing time of the treatment group was significantly better than that of the control group in reducing the wound area. The wound healing time of the two groups was significantly higher than that of the control group (P 0.05). The results showed that the treatment group was obviously superior to the control group in promoting wound healing: the total curative effect of the two groups on the 28th day after operation was 83.33 in the control group, 100 in the treatment group, and 28 days in the two groups. The difference was statistically significant, which indicated that the treatment group was superior to the control group in promoting wound healing. Conclusion: by analyzing the results of this study, we can conclude that the curative effect of purple and Shengji ointment dressing changing group after anal fistula is better than that of vaseline gauze exchange group, which is mainly reflected in the reduction and improvement of wound secretion and the relief of wound pain. Promote the growth of granulation and wound healing.
【學(xué)位授予單位】:福建中醫(yī)藥大學(xué)
【學(xué)位級別】:碩士
【學(xué)位授予年份】:2016
【分類號】:R266
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