本文選題：膝關(guān)節(jié)骨性關(guān)節(jié)炎 + 中藥湯劑��； 參考：《長春中醫(yī)藥大學(xué)》2016年碩士論文

【摘要】：目的:觀察自擬補腎益髓方治療膝關(guān)節(jié)骨性關(guān)節(jié)炎(肝腎不足型)的臨床療效。方法:本課題遵循隨機平行對照研究方法,對2015年1月至12月在長春中醫(yī)藥大學(xué)附屬醫(yī)院骨科門診患者,選擇符合該病的中西醫(yī)診斷標準的患者120例,隨機平行分為治療組和對照組,每組60例。對照組選擇的口服藥物為金烏骨通膠囊。兩組條件均衡:性別、年齡、病程、病情等差異無顯著性意義(P0.05)。對照組:口服藥物為金烏骨通膠囊,服用方法為每次1.5g,口服,每日3次,溫開水送服,連服1月。治療組:自擬補腎益髓方,水煎取汁150ml,早晚頓服,連服1月。整個課題過程安排2次訪視,第1次訪視時間為患者初入組時(即治療第1天),按入組時間先后順序分配給患者一個單獨的藥物編號,第2次訪視時間則安排在患者入組后療程結(jié)束時,分別對患者臨床癥狀的改善程度進行評估,以評估該湯劑口服的安全性與有效性。結(jié)果:兩組患者的治療結(jié)果顯示,對照組60例臨床控制4例、顯效28例、有效22例、無效6例,總體有效率為90.00%;治療組60例臨床控制6例、顯效25例、有效25例、無效4例,總有效率為93.33%。經(jīng)統(tǒng)計學(xué)分析,治療組的總體療效同對照組相當,且治療組在疼痛方面的改善程度優(yōu)于對照組。結(jié)論:治療組的總體療效同對照組相當,且治療組在疼痛方面的改善程度優(yōu)于對照組,值得臨床推廣。
[Abstract]:Objective: to observe the clinical effect of self-made prescription for tonifying kidney and tonifying marrow in the treatment of osteoarthritis of knee joint. Methods: according to the method of randomized parallel control study, 120 patients in orthopedic department of Changchun University of traditional Chinese Medicine from January to December 2015 were selected to meet the diagnostic criteria of traditional Chinese and Western medicine. They were randomly divided into treatment group (n = 60) and control group (n = 60). The oral drug of the control group was Jinwu Gutong capsule. There was no significant difference between the two groups in terms of sex, age, course of disease and disease condition (P 0.05). Control group: Jinwu Gutong capsule was taken orally, 1.5 g each time, 3 times a day, warm boiled water was given for 1 month. Treatment group: self-made tonifying kidney-tonifying pulp prescription, decoction 150 ml, morning and evening, take even for 1 month. During the whole course of the study, two visits were arranged. The first visit was made when the patient first entered the group (that is, on the first day of treatment), and was assigned a single drug number according to the time sequence of the first visit. The time of the second visit was arranged at the end of the course of treatment to evaluate the improvement of the clinical symptoms of the patients respectively in order to evaluate the safety and efficacy of the decoction. Results: the results of two groups showed that there were 60 cases of clinical control, 28 cases of remarkable effect, 22 cases of effective, 6 cases of ineffective, and 60 cases of clinical control of 6 cases, 25 cases of remarkable effect, 25 cases of effective and 4 cases of ineffectiveness in the treatment group, and the total effective rate was 90.005% in the treatment group, 60 cases of which were clinically controlled, 25 cases effective, 25 cases effective, 4 cases ineffective. The total effective rate was 93.33. Statistical analysis showed that the overall curative effect of the treatment group was similar to that of the control group, and the improvement of pain in the treatment group was better than that in the control group. Conclusion: the overall curative effect of the treatment group is equal to that of the control group, and the improvement of pain in the treatment group is better than that in the control group, which is worthy of clinical popularization.
【學(xué)位授予單位】：長春中醫(yī)藥大學(xué)
【學(xué)位級別】：碩士
【學(xué)位授予年份】：2016
【分類號】：R274.9

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