本文選題：加減藿樸夏苓湯 + 胃動力治療儀　； 參考：《湖南中醫(yī)藥大學(xué)》2016年碩士論文

【摘要】：目的:觀察加減藿樸夏苓湯配合胃動力儀治療功能性消化不良脾胃濕熱證患者的臨床療效及安全性。方法:將2015年1月~2016年1月收治的98例功能性消化不良脾胃濕熱證患者按照隨機(jī)數(shù)字表順序隨機(jī)分為綜合治療組35例,中藥治療組32例,西藥治療組31例。綜合治療組予加減藿樸夏苓湯口服,配合胃動力治療儀治療;中藥治療組予加減藿樸夏苓湯口服;西藥治療組予鹽酸伊托必利片、泮托拉唑鈉腸溶膠囊口服,三組療程均為2周。治療結(jié)束后對疾病療效、中醫(yī)證候總積分變化、VAS疼痛評分、不良反應(yīng)等方面進(jìn)行統(tǒng)計(jì)分析。結(jié)果:(1)綜合治療組總有效率為97.14%,中藥治療組總有效率為84.38%,西藥治療組總有效率為80.65%,綜合治療組與中藥治療組、綜合治療組與西藥治療組總有效率比較差異有統(tǒng)計(jì)學(xué)意義(P0.05),中藥治療組與西藥治療組比較差異無統(tǒng)計(jì)學(xué)意義(P0.05)。(2)中醫(yī)證候總積分變化,三組治療后與治療前比較差異有統(tǒng)計(jì)學(xué)意義(P0.05),治療后綜合治療組與中藥治療組比較、綜合治療組與西藥治療組比較、中藥治療組與西藥治療組比較,差異分別具有統(tǒng)計(jì)學(xué)意義(P0.05)。在改善脘腹脹滿癥狀三組兩兩比較差異分別具有統(tǒng)計(jì)學(xué)意義(P0.05);在改善胃脘疼痛、身重困倦、口干口苦癥狀,綜合治療組與中藥治療組比較,差異無統(tǒng)計(jì)學(xué)意義(P0.05),綜合治療組與西藥治療組、中藥治療組與西藥治療組比較,差異分別具有統(tǒng)計(jì)學(xué)意義(P0.05)。(3)上腹疼痛VAS評分,綜合治療組與中藥治療組、綜合治療組與西藥治療組、中藥治療組與西藥治療組比較差異分別具有統(tǒng)計(jì)學(xué)意義(P0.05)。(4)不良反應(yīng)觀察,綜合治療組與中藥治療組未出現(xiàn)明顯的不良反應(yīng)及毒副作用,西藥治療組出現(xiàn)腸鳴2例,腹瀉1例。結(jié)論:加減藿樸夏苓湯配合胃動力儀治療功能性消化不良脾胃濕熱證患者療效肯定,能有效緩解臨床癥狀,安全無副作用,值得臨床推廣。
[Abstract]:Objective: to observe the clinical efficacy and safety of Jiajiao Pu Xia Ling decoction combined with gastric motility instrument in the treatment of functional dyspepsia with dampness and heat of spleen and stomach. Methods: from January 2015 to January 2016, 98 cases of functional dyspepsia with damp-heat syndrome of spleen and stomach were randomly divided into comprehensive treatment group (n = 35), traditional Chinese medicine group (n = 32) and western medicine group (n = 31). The combined treatment group was treated with Xianhuapu Xialing decoction, combined with gastric motility therapy instrument; the traditional Chinese medicine treatment group was treated with Xianhuipuling decoction; the western medicine treatment group was treated with itopride hydrochloride tablets and pam Tora sodium enteric-soluble capsules. All the three groups were treated for 2 weeks. After the treatment, the effect of the disease, the total integral changes of TCM syndromes and VAS pain score, adverse reactions were statistically analyzed. Results the total effective rate of the comprehensive treatment group was 97.145.The total effective rate of the traditional Chinese medicine treatment group was 84.38, and the total effective rate of the western medicine treatment group was 80.65.The total effective rate of the comprehensive treatment group and the traditional Chinese medicine treatment group was 84.38, and the total effective rate of the western medicine treatment group was 80.65. The difference of total effective rate between the comprehensive treatment group and the western medicine treatment group was statistically significant (P 0.05), but there was no significant difference between the traditional Chinese medicine treatment group and the western medicine treatment group. There was significant difference between the three groups after treatment and before treatment (P 0.05). There were significant differences between the comprehensive treatment group and the traditional Chinese medicine treatment group, the comprehensive treatment group and the western medicine treatment group, and the traditional Chinese medicine treatment group and the western medicine treatment group after treatment. There were statistically significant differences among the three groups in improving the symptoms of epigastric distention and fullness, and in the improvement of epigastric pain, heavy sleepiness, dry-mouth bitter symptoms, and comparison between the comprehensive treatment group and the traditional Chinese medicine treatment group. The difference was not statistically significant (P 0.05). The VAS score of upper abdominal pain was significantly higher in the comprehensive treatment group than in the western medicine treatment group, the traditional Chinese medicine treatment group and the western medicine treatment group. The VAS scores of upper abdominal pain in the combined treatment group and the traditional Chinese medicine treatment group were significantly higher than those in the traditional Chinese medicine group. There were significant differences in adverse reactions between the comprehensive treatment group and the western medicine treatment group, the traditional Chinese medicine treatment group and the western medicine treatment group, respectively (P 0.05. 05. 4). There were no obvious adverse reactions and side effects in the comprehensive treatment group and the traditional Chinese medicine treatment group, and there were no significant adverse reactions and side effects in the comprehensive treatment group and the traditional Chinese medicine treatment group. In the western medicine treatment group, there were 2 cases of intestinal tinnitus and 1 case of diarrhea. Conclusion: the treatment of functional dyspepsia of spleen and stomach dampness and heat syndrome by adding and reducing Huopu Pu Xia Ling decoction and gastric motility instrument is effective in relieving clinical symptoms, safety and no side effects, and is worth popularizing clinically.
【學(xué)位授予單位】：湖南中醫(yī)藥大學(xué)
【學(xué)位級別】：碩士
【學(xué)位授予年份】：2016
【分類號】：R259

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