本文選題：肺癌 + 辨證分型��； 參考：《北京中醫(yī)藥大學(xué)》2017年碩士論文

【摘要】：研究目的1、探討我院2015年12月至2016年12月在廣安門醫(yī)院腫瘤科門診納入的135例原發(fā)性支氣管肺癌患者中醫(yī)辨證分型中實證的特點。2、研究原發(fā)性支氣管肺癌各實證證候的比例,與性別、組織病理類型、卡氏評分及臨床分期的關(guān)系,各實證證候間的相互關(guān)系。研究方法選取國家標準、行業(yè)標準及相關(guān)中醫(yī)書籍中關(guān)于實證的診斷條目,依據(jù)臨床上原發(fā)性支氣管肺癌的發(fā)病特點、臨床癥狀,以證素為核心,采用多層級診斷的方法為基礎(chǔ),結(jié)合張培彤教授的臨床經(jīng)驗初步擬定各肺癌實性證候的診斷標準,制作相應(yīng)的觀察表,根據(jù)納入標準和排除標準篩選患者,使用EPIdata軟件錄入135例肺癌患者癥狀。使用Excel、SPSS19軟件統(tǒng)一辨證,進行統(tǒng)計學(xué)分析,運用卡方檢驗分析各實證證候與性別、組織病理類型、卡氏評分及臨床分期的關(guān)系。多證組合與臨床分期的關(guān)系,以及各實證相互間的關(guān)系。研究結(jié)果1、各實證證候的比例氣滯證患者132例,占97.78%,氣逆證患者132例,占97.78%,痰凝證患者97例,占71.85%,血瘀證患者71例,占52.59%,實熱證患者28例,占20.74%,飲停證患者20例,占14.81%,濕阻證患者16例,占11.85%,血熱證患者14例,占10.37%,血寒證患者8例,占5.93%,實寒證患者8例,占5.930%,水停證患者5例,占3.70%,氣閉證患者0例,占0%。2、各實證證候與性別、組織病理類型、卡氏評分及臨床分期的關(guān)系氣滯證與非氣滯證患者在性別、組織病理類型、KPS評分、及臨床分期上沒有顯著的統(tǒng)計學(xué)意義上的差異;氣逆證與非氣逆證患者在性別及KPS評分上沒有顯著的統(tǒng)計學(xué)意義上的差異,在組織病理分型及臨床分期上有顯著的統(tǒng)計學(xué)意義上的差異;血瘀證與非血瘀證患者在性別、KPS評分及臨床分期上沒有顯著的統(tǒng)計學(xué)意義上的差異,在組織病理分型上有顯著的統(tǒng)計學(xué)意義上的差異;血寒證與非血寒證患者在性別、KPS評分、組織病理分型及臨床分期上沒有顯著的統(tǒng)計學(xué)意義上的差異;血熱證與非血熱證患者在性別、KPS評分、組織病理類型、及臨床分期上沒有顯著的統(tǒng)計學(xué)意義上的差異;痰凝證與非痰凝證患者在性別、KPS評分、組織病理類型、及臨床分期上沒有顯著的統(tǒng)計學(xué)意義上的差異;飲停證與非飲停證患者在性別、KPS評分、組織病理類型、及臨床分期上沒有顯著的統(tǒng)計學(xué)意義上的差異;濕阻證與非濕阻證患者在性別、KPS評分、組織病理類型、及臨床分期上沒有顯著的統(tǒng)計學(xué)意義上的差異;水停證與非水停證患者在性別、組織病理類型、及臨床分期上沒有顯著的統(tǒng)計學(xué)意義上的差異,在KPS評分上有顯著的統(tǒng)計學(xué)意義上的差異;實熱證與非實熱證患者在性別、KPS評分及臨床分期上沒有顯著的統(tǒng)計學(xué)意義上的差異,在組織病理類型上有顯著的統(tǒng)計學(xué)意義上的差異;實寒證與非實寒證患者在性別、KPS評分、組織病理類型、及臨床分期上沒有顯著的統(tǒng)計學(xué)意義上的差異。3、多證組合及實證證候相互關(guān)系本研究共納入135例病例,研究其中實證證候的組合,在135例肺癌患者中,(1)單證出現(xiàn)2例,占1.48%,其中氣滯證2例,占100%。(2)二證組合:共12例,占8.89%。其中氣滯證+氣逆證11例,占91.67%;氣滯證+血瘀證1例,占8.33%。(3)三證組合:共33例,占24.44%。其中氣滯證+氣逆證+痰凝證19例,占57.58%;氣滯證+氣逆證+血瘀證6例,占18.18;氣滯證+氣逆證+實熱證2例,占6.06%;氣滯證+氣逆證+血寒證2例,占6.06%;氣滯證+氣逆證+飲停證1例,占3.03%;氣逆證+血瘀證+痰凝證1例,占3.03%;氣逆證+痰凝證+濕阻證1例,占3.03%;氣逆證+痰凝證+實寒證1例,占3.03%。(4)四證組合:共48例,占35.56%。其中氣滯證+氣逆證+血瘀證+痰凝證23例,占47.92%;氣滯證+氣逆證+血瘀證+實熱證8例,占16.67%;氣滯證+氣逆證+痰凝證+實寒證5例,占10.42%;氣滯證+氣逆證+血瘀證+血熱證2例,占4.17%;氣滯證+氣逆證+血瘀證+濕阻證2例,占4.17%;氣滯證+氣逆證+痰凝證+飲停證2例,占4.17%;氣滯證+氣逆證+痰凝證+實熱證2例,占4.17%;氣滯證+氣逆證+血瘀證+血寒證1例,占2.08%;氣滯證+氣逆證+痰凝證+血熱證1例,占2.08%;氣滯證+氣逆證+痰凝證+濕阻證1例,占2.08%;氣滯證+氣逆證+痰凝證+水停證1例,占2.08%。(5)五證組合:共30例,占22.22%。其中氣滯證+氣逆證+血瘀證+痰凝證+血熱證5例,占16.67%;氣滯證+氣逆證+血瘀證+痰凝證+實熱證5例,占16.67%;氣滯證+氣逆證+血瘀證+痰凝證+飲停證4例,占13.33%;氣滯證+氣逆證+血瘀證+痰凝證+濕阻證3例,占10%;氣滯證+氣逆證+痰凝證+飲停證+實熱證3例,占10%;氣滯證+氣逆證+血瘀證+痰凝證+水停證2例,占6.67%;氣滯證+氣逆證+痰凝證+飲停證+濕阻證2例,占6.67%;氣滯證+氣逆證+血瘀證+痰凝證+血寒證1例,占3.33%;氣滯證+氣逆證+血熱證+痰凝證+實熱證1例,占3.33%;氣滯證+氣逆證+血熱證+痰凝證+濕阻證1例,占3.33%;氣滯證+氣逆證+痰凝證+飲停證+實寒證1例,占3.33%;氣滯證+氣逆證+痰凝證+濕阻證+實熱證1例,占3.33%;氣滯證+氣逆證+痰凝證+濕阻證+實寒證1例,占3.33%。(6)六證組合:共6例,占4.44%。其中氣滯證+氣逆證+血瘀證+痰凝證+飲停證+實熱證2例,占33.33%;氣滯證+氣逆證+血寒證+血熱證+痰凝證+實熱證1例,占16.67%;氣滯證+氣逆證+血瘀證+血寒證+痰凝證+飲停證1例,占16.67%;氣滯證+氣逆證+血瘀證+血寒證+痰凝證+濕阻證1例,占16.67%;氣滯證+氣逆證+血瘀證+痰凝證+濕阻證+實熱證1例,占16.67%。(7)七證組合:共4例,占2.96%。其中氣滯證+氣逆證+血瘀證+血熱證+痰凝證+飲停證+實熱證1例,占25.00%;氣滯證+氣逆證+血寒證+血熱證+痰凝證+飲停證+濕阻證1例,占25.00%;氣滯證+氣逆證+血瘀證+血熱證+痰凝證+飲停證+水停證1例,占25.00%;氣滯證+氣逆證+痰凝證+飲停證+濕阻證+水停證+實熱證1例,占25.00%。其中單一證候Ⅳ期0例,占0.00%;二證組合Ⅳ期5例,占41.67%;三證組合Ⅳ期13例,占39.39%;四證組合IV期20例,占41.67%;五證組合Ⅳ期13例,占43.33%;六證組合IV期5例,占83.33%;七證組合Ⅳ期2例,占20%。當(dāng)出現(xiàn)氣滯證的時候,氣逆證伴隨出現(xiàn)的概率最高,為97.73%,其次是痰凝證71.21%、血瘀證53.03%、實熱證21.21%、飲停證15.15%、濕阻證11.36%、血熱證10.61%。伴隨出現(xiàn)概率較低的有血寒證6.06%、實寒證5.30%、水停證3.79%。當(dāng)出現(xiàn)氣逆證的時候,氣滯證伴隨出現(xiàn)的概率最高,為97.73%,其次是痰凝證73.48%、血瘀證53.03%、實熱證21.21%、飲停證15.15%、濕阻證12.12%、血熱證10.61%。伴隨出現(xiàn)概率較低的有血寒證6.06%、實寒證6.06%、水停證3.79%。當(dāng)出現(xiàn)血瘀證的時候,氣滯證與氣逆證伴隨出現(xiàn)的概率最高,為98.59%,其次是痰凝證71.83%、實熱證23.94%、血熱證12.68%、飲停證12 68%。伴隨出現(xiàn)概率較低的有濕阻證9.86%、血寒證5.63%、水停證4.23%。在本研究中,當(dāng)血瘀證出現(xiàn)時,實寒證出現(xiàn)的病例數(shù)為0。當(dāng)出現(xiàn)血寒證的時候,氣逆證和氣滯證伴隨出現(xiàn)概率的最高,為100.00%,其次是痰凝證62.50%、血瘀證50.00%、血熱證25.00%、飲停證25.00%、濕阻證25.00%、實熱證12.500%。在本研究中,當(dāng)血寒證出現(xiàn)時,水停證和實寒證出現(xiàn)的病例數(shù)為0。當(dāng)出現(xiàn)血熱證的時候,氣逆證和氣滯證伴隨出現(xiàn)的概率最高,為100.00%,其次是痰凝證85.71%、血瘀證64.29%、飲停證21.43%、實熱證21.43%、血寒證14.29%、濕阻證14.29%,伴隨出現(xiàn)概率較低的有水停證7.14%。在本研究中,當(dāng)出現(xiàn)血熱證時,實寒證出現(xiàn)的病例數(shù)為0。當(dāng)出現(xiàn)痰凝證的時候,氣逆證和氣滯證伴隨出現(xiàn)的概率最高,分別為100.00%、96.91%,其次是血瘀證52.58%、實熱證18.56%、濕阻證14.43%、血熱證12.37%。伴隨出現(xiàn)概率較低的有實寒證8.25%、血寒證5.15%、水停證5.15%。當(dāng)出現(xiàn)飲停證的時候,氣逆證和氣滯證伴隨出現(xiàn)的概率最高,為100.00%,其次是痰凝證95.00%、血瘀證45.00%、實熱證35.00%、濕阻證20.00%、血熱證15.00%、血寒證10.00%、水停證10.00%。伴隨出現(xiàn)概率較低的是實寒證5.00%。當(dāng)出現(xiàn)濕阻證的時候,氣逆證和氣滯證伴隨出現(xiàn)的概率最高,分別為100.00%、93.75%,其次是痰凝證87.500%、血瘀證43.75%、飲停證25.00%、實熱證18.75%、血寒證12.50%、血熱證12.50%。伴隨出現(xiàn)概率較低的是水停證和實寒證,占6.25%。當(dāng)出現(xiàn)水停證的時候,氣逆證、氣滯證及痰凝伴隨出現(xiàn)的概率最高,為100.00%,其次是血瘀證60.00%、飲停證40.00%、血熱證20.00%、濕阻證20.00%、實熱證20.00%。本研究中出現(xiàn)水停證時,出現(xiàn)血寒證和實寒證的病例數(shù)為0。當(dāng)出現(xiàn)實寒證的時候,氣逆證和痰凝證伴隨出現(xiàn)的概率最高,為100.00%,其次是氣滯證87.50%、飲停證12.50%、濕阻證12.50%。本研究中出現(xiàn)實寒證時,出現(xiàn)血瘀證、血寒證、血熱證、水停證、實熱證的病例數(shù)為0。當(dāng)出現(xiàn)實熱證的時候,氣逆證和氣滯證伴隨出現(xiàn)的概率最高,為100.00%,其次是痰凝證64.29%、血瘀證60.71%、飲停證25.00%、血熱證10.71%、濕阻證10.71%。伴隨出現(xiàn)概率較低的有血寒證3.57%、水停證3.57%。本研究中出現(xiàn)實熱證時,出現(xiàn)實寒證的病例數(shù)為0。當(dāng)將實證證候兩兩分組統(tǒng)計一同出現(xiàn)的頻數(shù)時,其中出現(xiàn)頻數(shù)較高的依次是:氣滯證+氣逆證129例,占95.56%;氣逆證+痰凝證97例,占71.85%;氣滯證+痰凝證94例,占69.63%;氣滯證+血瘀證70例,占51.85%;氣逆證+血瘀證70例,占51.85%;血瘀證+痰凝證51例,占37.78%。結(jié)論通過對納入本研究的135例原發(fā)性支氣管肺癌患者的臨床調(diào)查發(fā)現(xiàn):1、在各實證證候中,出現(xiàn)頻率由高到低分別為:氣滯證、氣逆證、痰凝證、血瘀證、實熱證、飲停證、濕阻證、血熱證、血寒證、實寒證、水停證。2、氣逆證患者與非氣逆證患者在組織病理分型及臨床分期上有統(tǒng)計學(xué)意義上的差異;血瘀證患者與非血瘀證患者在組織病理分型上有統(tǒng)計學(xué)意義上的差異;水停證患者與非水停證患者在KPS評分上有統(tǒng)計學(xué)意義上的差異;實熱證患者與非實熱證患者在組織病理分型上有統(tǒng)計學(xué)意義上的差異;余實證證候與患者的性別、KPS評分、組織病理分型及臨床分期無顯著統(tǒng)計學(xué)意義上的差異。3、多證同時出現(xiàn)的幾率較單證為多見,四證組合出現(xiàn)的幾率最高,多證組合多見于晚期肺癌患者。各實證證候與氣滯證、氣逆證的關(guān)系最為密切,其次是痰凝證和血瘀證。其中氣滯證+氣逆證、氣逆證+痰凝證、氣滯證+痰凝證、氣滯證+血瘀證、氣逆證+血瘀證、血瘀證+痰凝證易并見。
[Abstract]:The purpose of this study was to investigate the characteristics of 135 cases of primary bronchogenic cancer patients in our hospital from December 2015 to December 2016 in the oncology clinic of Guanganmen hospital,.2, to study the proportion of the syndromes of primary bronchogenic carcinoma, the relationship with sex, histopathological type, Cartesian score and clinical staging. The relationship between syndromes and syndromes. The research methods selected national standards, industry standards and related diagnostic items in traditional Chinese medicine books, based on the characteristics of clinical primary bronchogenic lung cancer, clinical symptoms, syndrome elements as the core, the multi-layer diagnosis method as the basis, combined with Professor Zhang Peitong's clinical experience preliminarily drawn up. The diagnostic criteria for the syndrome of lung cancer were made, and the corresponding observation table was made. According to the inclusion criteria and exclusion criteria, 135 cases of lung cancer patients were recorded by EPIdata software. Excel, SPSS19 software was used for statistical analysis, and statistical analysis was carried out, and chi square test was used to analyze the syndrome and sex, histopathological type, and KASH score. The relationship between the clinical staging and clinical staging, the relationship between the clinical stages and the clinical staging. Results 1, 132 cases of qi stagnation syndrome, 132 cases of Qi inverse syndrome, 97 cases of phlegm coagulation syndrome, 71.85%, 71 cases of blood stasis syndrome, 52.59% of blood stasis syndrome, 28 cases of real heat syndrome, 20.74%, drinking and stopping. There were 20 cases, 14.81%, 16 cases of damp resistance syndrome, 11.85%, 14 cases of blood heat syndrome, 10.37%, 8 cases of blood cold syndrome, 5.93%, 8 cases of real cold syndrome, 5.930%, 5 cases of water stop syndrome, 3.70%, 0%.2, the relationship between syndrome and pathological type, Chi's score and clinical stages There was no significant difference in sex, histopathological type, KPS score, and clinical staging of patients with qi stagnation; there was no significant difference in gender and KPS score in the patients with Qi inverse syndrome and non gas inverse syndrome, and there were significant differences in the histopathological classification and clinical stages; blood stasis. There was no significant difference in sex, KPS score and clinical staging of the patients with syndrome and non blood stasis syndrome, and there were significant differences in histopathological classification. There was no significant difference in gender, KPS score, histopathological classification and clinical staging of the blood cold syndrome and non blood cold syndrome. There was no significant difference in sex, KPS score, histopathological type, and clinical staging of patients with blood heat syndrome and non blood heat syndrome. There was no significant difference in gender, KPS score, histopathological type, and clinical staging of patients with phlegm and non phlegm coagulating syndrome. There was no significant difference in KPS score, histopathological type, and clinical staging; there was no significant difference in gender, KPS score, histopathological type, and clinical staging of patients with dampness syndrome and non dampness syndrome, and the sex, histopathological type, and clinical staging of patients with water stop and non water stop syndrome. There is no significant statistical difference, there is significant difference in statistical significance on KPS score; there is no significant statistical difference between the patients with real heat syndrome and non real heat syndrome in sex, KPS score and clinical stage, and there are significant differences in the sense of unification on the histopathological types; the real cold syndrome and the non real cold syndrome have a significant difference. There was no significant difference in sex, KPS score, histopathological type, and clinical staging of.3, the multiple syndrome combination and the correlation of empirical syndrome were included in 135 cases, and the combination of empirical syndromes was studied. Among 135 patients with lung cancer, (1) 2 cases, accounting for 1.48%, 2 cases of qi stagnation, accounting for 100%. (2) two. Syndrome combination: a total of 12 cases, accounting for 11 cases of qi stagnation syndrome + Qi inverse syndrome in 8.89%., 1 cases of qi stagnation and blood stasis syndrome, accounting for 33 cases (3), accounting for 57.58%, qi stagnation syndrome + Qi inverse syndrome + blood stasis syndrome in 57.58%, qi stagnation + Qi reverse syndrome + blood stasis in 6 cases, 18.18, qi stagnation + Qi inverse syndrome + solid heat syndrome 2, 6.06%; Qi Stagnation Syndrome + Qi inverse syndrome + blood, and qi stagnation syndrome + Qi inverse syndrome + blood 2 cases of cold syndrome, accounting for 6.06%, qi stagnation syndrome + Qi inverse syndrome + drinking stop syndrome in 1 cases, accounting for 3.03%, Qi inverse syndrome + blood stasis syndrome + coagulation syndrome 1 cases, 3.03%; Qi inverse syndrome + phlegm coagulation + damp resistance syndrome 1 cases, 3.03%; Qi inverse syndrome + phlegm coagulating syndrome + 1 cases, accounting for 3.03%. (4) four syndrome, altogether 48 cases, accounting for qi stagnation syndrome + Qi reverse syndrome + phlegm coagulating syndrome 23 cases, accounting for 47.92%; Qi Stagnation Syndrome + +; Qi Stagnation Syndrome + + Qi Stagnation Syndrome + blood stasis syndrome + solid heat syndrome, accounting for 16.67%, qi stagnation + Qi inverse syndrome + phlegm coagulation + solid cold syndrome 5 cases, accounting for 10.42%, qi stagnation + Qi inverse syndrome + blood stasis syndrome + blood heat syndrome 2 cases, 4.17%; Qi stagnation + Qi reverse syndrome + blood stasis syndrome + damp resistance syndrome 2 cases, 4.17%; Qi stagnation + Qi reverse syndrome + phlegm coagulating syndrome + stopping syndrome 2 cases, 4.17%; Qi stagnation + Qi reverse syndrome + phlegm coagulation + phlegm coagulating syndrome + solid heat syndrome 2 4.17% cases, 1 cases of qi stagnation syndrome + Qi inverse syndrome + blood stasis syndrome + blood cold syndrome, accounting for 2.08%, qi stagnation + Qi inverse syndrome + phlegm coagulation + blood heat syndrome in 1 cases, accounting for 2.08%, qi stagnation + Qi reverse syndrome + phlegm coagulation syndrome + damp syndrome 1 cases, 2.08%, qi stagnation + Qi reverse syndrome + phlegm coagulation syndrome + 1 cases, accounting for 2.08%. (5) five syndrome combination: 30 cases, accounting for qi stagnation syndrome + Qi inverse syndrome + blood stasis syndrome + phlegm in the case of qi stagnation syndrome + Qi reverse syndrome + blood stasis syndrome + blood stasis syndrome. 5 cases of coagulant syndrome + blood heat syndrome, accounting for 16.67%, qi stagnation + Qi inverse syndrome + blood stasis syndrome + solid heat syndrome + 5 cases, accounting for 16.67%, qi stagnation + Qi reverse syndrome + blood stasis syndrome + stagnation of phlegm + stop syndrome 4 cases, 13.33%; Qi stagnation + Qi reverse syndrome + blood stasis syndrome + phlegm syndrome + damp resistance syndrome 3 cases, 10%; Qi stagnation + Qi reverse syndrome + phlegm coagulating syndrome + solid heat syndrome + 3 cases, 10%; Qi Stagnation Syndrome + Qi inverse Syndrome + blood stasis syndrome + phlegm coagulation syndrome + water stop syndrome, accounting for 6.67%, qi stagnation + Qi reverse syndrome + phlegm coagulating syndrome + damp resistance syndrome (6.67%), accounting for 6.67%, qi stagnation + Qi reverse syndrome + blood stasis syndrome + blood cold syndrome 1 cases, accounting for 3.33%; Qi stagnation + Qi reverse syndrome + blood heat syndrome + phlegm coagulation + solid heat syndrome 1 cases, accounting for 3.33%; Qi stagnation + Qi reverse syndrome + blood heat syndrome + phlegm coagulation syndrome + damp resistance syndrome 1 cases, accounting for 3.33%; Qi Stagnation Syndrome + Qi inverse syndrome + phlegm coagulating syndrome + drinking stop syndrome + solid cold syndrome 1 cases, accounting for 3.33%; Qi Stagnation Syndrome + Qi inverse syndrome + phlegm coagulating syndrome + solid heat syndrome 1 cases, accounting for 3.33%; Qi Stagnation Syndrome + Qi reverse syndrome + phlegm coagulating syndrome + solid cold 1 cases, accounting for 6) six combination: 6 cases, accounting for qi stagnation + Qi reverse syndrome + blood stasis syndrome + phlegm coagulation + drink stop syndrome + solid heat syndrome, 2 cases, accounting for 33.3 3%, 1 cases of qi stagnation + Qi inverse syndrome + blood cold syndrome + blood heat syndrome + phlegm coagulation + solid heat syndrome, accounting for 16.67%, 1 cases of qi stagnation syndrome + Qi reverse syndrome + blood stasis syndrome + phlegm coagulation + drink stop syndrome, accounting for 16.67%, 1 cases of qi stagnation syndrome + Qi inverse syndrome + blood stasis syndrome + blood cold syndrome + phlegm coagulation + damp resistance syndrome, 16.67%, qi stagnation syndrome + Qi reverse syndrome + blood stasis syndrome + phlegm coagulation + damp resistance syndrome + solid heat syndrome 1 cases, accounting for 16.67%. (7) seven syndromes: a total of 4 cases, accounting for 4 cases of qi stagnation syndrome + Qi inverse syndrome + blood stasis syndrome + blood heat syndrome + phlegm coagulating syndrome + solid heat syndrome 1 cases, accounting for 25%; Qi stagnation + Qi inverse syndrome + blood cold syndrome + blood heat syndrome + phlegm coagulating syndrome + damp resistance 1 cases, accounting for 25%; Qi stagnation + Qi reverse syndrome + blood stasis syndrome + blood heat syndrome + phlegm coagulation + water stop syndrome 1 cases, accounting for 25%; Qi stagnation; Qi stagnation. Syndrome + gas inverse syndrome + phlegm coagulating syndrome + drink stop syndrome + water stop + water stop + solid heat syndrome, accounting for 1 cases of 25.00%., which accounted for 0 cases of single syndrome IV, accounting for 0%, two syndrome group IV 5 cases, 41.67%, 13 cases in 13 cases, 39.39%; four syndrome group IV 20 cases, 41.67%; five syndrome IV period 13 cases, occupy 43.33%; six syndrome combination IV phase IV cases Period 2 cases, accounting for 20%. when the syndrome of qi stagnation, gas inverse syndrome with the highest probability of 97.73%, followed by phlegm coagulation 71.21%, blood stasis syndrome 53.03%, solid heat syndrome 21.21%, drink stop 15.15%, dampness syndrome 11.36%, blood fever syndrome 10.61%. accompanied by low probability of blood cold 6.06%, the real cold syndrome 5.30%, water stop 3.79%. when the gas inverse syndrome, when the water stop syndrome occurs, when the Qi inverse syndrome appears, the water stop license 3.79%. appears Qi inverse syndrome, when water stop license appears Qi Qi syndrome, The incidence of qi stagnation syndrome was 97.73%, followed by phlegm coagulation 73.48%, blood stasis syndrome 53.03%, solid heat syndrome 21.21%, drinking stop syndrome 15.15%, damp resistance 12.12%, blood heat syndrome 10.61%. accompanied by low probability of cold syndrome 6.06%, real cold syndrome 6.06%, and water stop syndrome when blood stasis syndrome appeared, qi stagnation syndrome and Qi inverse syndrome accompanied with the probability of occurrence. The highest was 98.59%, followed by phlegm coagulation 71.83%, solid heat syndrome 23.94%, blood heat syndrome 12.68%, drinking stop syndrome 12 68%. accompanied by low probability of damp resistance 9.86%, blood cold 5.63%, water stop syndrome 4.23%. in this study, when blood stasis syndrome appeared, the number of cases of real cold syndrome was 0. when the blood cold syndrome appeared, Qi inverse syndrome and qi stagnation syndrome accompanied the appearance of almost all the occurrence of almost all the appearance of the occurrence of the syndrome of qi stagnation and qi stagnation. The highest rate was 100%, followed by phlegm coagulation 62.50%, blood stasis syndrome 50%, blood heat syndrome 25%, drink stop syndrome 25%, damp resistance syndrome 25%, 12.500%. in this study, when the blood cold syndrome appeared, the number of cases of water stop and real cold syndrome was 0. when there was blood heat syndrome, and the highest probability of occurrence of Qi reverse syndrome and qi stagnation syndrome was 100%. The second is phlegm coagulating syndrome 85.71%, blood stasis syndrome 64.29%, drinking stop syndrome 21.43%, solid heat syndrome 21.43%, blood cold syndrome 14.29%, damp resistance syndrome 14.29%, accompanied with low probability of water stop syndrome in this study, when the occurrence of blood heat syndrome 7.14%., when there is a syndrome of blood heat, the number of cases of real cold syndrome is 0. when there is phlegm coagulating syndrome, the probability of occurrence of Qi inverse syndrome and qi stagnation syndrome is the highest, 100%, 96.91%, followed by blood stasis syndrome 52.58%, solid heat syndrome 18.56%, dampness syndrome 14.43%, blood heat syndrome 12.37%. with low incidence of cold syndrome 8.25%, blood cold 5.15%, water stop syndrome 5.15%. when drinking and stopping syndrome, gas inverse syndrome and Qi Stagnation with the highest probability of 100%, followed by phlegm 95%, blood stasis 45 %, 35% of real heat syndrome, 20% of damp resistance syndrome, 15% of blood heat syndrome, 10% of blood heat syndrome, 10% of blood cold syndrome, the lower probability of 10.00%. in water stop syndrome is the highest probability of occurrence of qi stagnation syndrome and qi stagnation syndrome, 100%, 93.75%, respectively, 87.500% of phlegm coagulation, 43.75% of blood stasis, 25% of blood stasis, 25% of stagnation of blood, and 18.7 heat syndrome. 18.7 5%, blood cold syndrome 12.50%, the incidence of blood heat syndrome 12.50%. with lower incidence of water stop syndrome and real cold syndrome, accounting for 6.25%. when the emergence of water withdrawal syndrome, gas inverse syndrome, qi stagnation syndrome and phlegm coagulation accompanied by the highest probability of 100%, followed by blood stasis syndrome 60%, drink stop 40%, blood heat syndrome 20%, damp resistance 20%, real heat syndrome in the 20.00%. study appeared in this study When the water was stopped, the number of cases of blood cold and real cold syndrome was 0.. When the real cold syndrome appeared, the highest probability of occurrence of Qi reverse syndrome and phlegm coagulation syndrome was 100%, followed by qi stagnation syndrome (87.50%), drinking stop syndrome (12.50%), and cold syndrome (12.50%.) in the study of damp syndrome, blood stasis syndrome, blood cold syndrome, blood heat syndrome, water stop syndrome and real heat syndrome cases were found. When the number was 0., when there was a solid heat syndrome, the incidence of qi stagnation syndrome and qi stagnation syndrome was the highest, 100%, followed by phlegm coagulation 64.29%, blood stasis syndrome 60.71%, drinking stop syndrome 25%, blood heat syndrome 10.71%, damp syndrome 10.71%. accompanied by low probability of blood cold 3.57%, water stop syndrome in 3.57%. this study appeared real cold syndrome. The number of cases was 0. when the number of 22 groups of empirical syndromes appeared together. The higher frequency was: Qi Stagnation Syndrome + Qi inverse syndrome in 129 cases, accounting for 95.56%, 97 cases of qi stagnation and phlegm coagulation syndrome, 71.85%; Qi Stagnation Syndrome + coagulation syndrome 94 cases, 69.63%; Qi stagnation + blood stasis 70 cases, 51.85%; Qi inverse syndrome + blood stasis syndrome 70, 51.85%; blood stasis syndrome + sputum. 51 cases of coagulant evidence, accounting for 37.78%. conclusion, were found through the clinical investigation of 135 cases of primary bronchogenic carcinoma in this study: 1, in each case, the frequency from high to low were as follows: Qi stagnation, Qi reverse syndrome, phlegm coagulating syndrome, blood stasis syndrome, solid heat syndrome, drinking stop syndrome, damp resistance syndrome, blood heat syndrome, blood cold syndrome, cold syndrome, water stop.2, Qi inverse syndrome There were statistically significant differences in histopathological classification and clinical staging of patients with non gas inverse syndrome. There were statistical differences between the patients with blood stasis syndrome and non blood stasis syndrome in the histopathological classification; there were statistical differences between the patients with water stop and the non water stop syndrome in the KPS score; the patients with real heat syndrome and non solid heat syndrome had a significant difference. There were statistically significant differences in histopathological typing, excess sex syndrome, sex, KPS score, histopathological classification and clinical stage.

【學(xué)位授予單位】：北京中醫(yī)藥大學(xué)
【學(xué)位級別】：碩士
【學(xué)位授予年份】：2017
【分類號】：R273

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