劉建秋教授治療AECOPD的經(jīng)驗(yàn)及用藥規(guī)律研究
發(fā)布時(shí)間:2018-05-12 23:46
本文選題:AECOPD + 經(jīng)驗(yàn); 參考:《黑龍江中醫(yī)藥大學(xué)》2016年碩士論文
【摘要】:目的:利用統(tǒng)計(jì)軟件分析劉建秋教授治療AECOPD的方藥,探討其用藥規(guī)律,總結(jié)劉教授治療本病的經(jīng)驗(yàn)。方法:經(jīng)驗(yàn)總結(jié)部分采用跟師出診,向師請(qǐng)教學(xué)習(xí)的方式,深入了解老師對(duì)AECOPD的認(rèn)識(shí)和治療經(jīng)驗(yàn)。用藥規(guī)律研究部分所收集的處方,均來(lái)源于2014年11月-2015年11月間就診于黑龍江中醫(yī)藥大學(xué)附屬第一醫(yī)院呼吸科門(mén)診和病房,經(jīng)劉建秋教授診療的AECOPD患者,根據(jù)納入排除標(biāo)準(zhǔn),共納入85個(gè)方劑。對(duì)85個(gè)方劑建立原始數(shù)據(jù)庫(kù)。運(yùn)用Microsoft Excel 2003軟件從用藥頻數(shù)、性味歸經(jīng)、功效方面來(lái)進(jìn)行用藥頻數(shù)的統(tǒng)計(jì),用SPSS19.0軟件對(duì)頻數(shù)大于等于20的進(jìn)行聚類(lèi)分析。結(jié)果:在85個(gè)方中共涉及104味中藥,共出現(xiàn)1173頻數(shù)。其中頻數(shù)≥40次的有11味藥,總共出現(xiàn)612次,占總數(shù)的52.17%,分別為半夏、苦杏仁、枇杷葉、瓜萎、萊菔子、紫蘇子、白前、金銀花、白果、甘草。從藥物的性味歸經(jīng)上分析,可以看出藥以溫性為主,寒性第二,平性第三;五味中苦味居第一位,辛味次之,甘味第三;可以看出多數(shù)藥物入肺、胃、脾、大腸、肝、腎經(jīng);經(jīng)過(guò)對(duì)藥物功效的統(tǒng)計(jì),化痰止咳平喘藥使用頻數(shù)最高,其次為補(bǔ)虛藥、清熱藥、解表藥、消食藥、活血化瘀藥、理氣藥等,理氣和活血化瘀藥的使用頻數(shù)接近。根據(jù)聚類(lèi)分析結(jié)果結(jié)合臨床實(shí)際應(yīng)用,共形成4個(gè)聚類(lèi)方。C1:紫蘇子、苦杏仁、瓜萎、甘草、半夏、枇杷葉、萊菔子、白前、陳皮、桔梗。C2:麻黃、白果、補(bǔ)骨脂。C3:沙參、麥冬、金銀花。C4:茯苓、酸棗仁、白芍、郁金。結(jié)論:1.劉建秋教授認(rèn)為A ECOPD患者久病肺虛痰濁潴留、水飲內(nèi)生,由于各種誘因?qū)е录毙园l(fā)作。2.劉建秋教授治療AECOPD采用解表祛邪、化痰祛瘀、扶正固本之法。3.劉建秋教授治療AECOPD核心用藥為半夏、苦杏仁、枇杷葉、瓜蔞、萊菔子、紫蘇子、白前、金銀花、白果、甘草。4.劉建秋教授治療AECOPD藥物主要性味歸經(jīng)是溫、寒、平,苦、辛、甘,肺、胃、脾、大腸經(jīng)。5.劉建秋教授治療AECOPD以化痰止咳平喘藥、補(bǔ)虛藥、清熱藥為主,兼用理氣和活血化瘀藥。6.劉建秋教授化痰平喘的用藥法則是“清燥溫理,宣降斂納”。
[Abstract]:Objective: to analyze the prescription of Professor Liu Jianqiu in the treatment of AECOPD by using statistical software, to discuss the rule of its use, and to summarize the experience of Professor Liu in treating this disease. Methods: in the part of experience summing up, we should follow the teacher and consult the teacher to learn more about the teacher's knowledge and treatment of AECOPD. The prescriptions collected in the study of drug use law were obtained from the outpatient clinic and ward of respiratory department of the first affiliated Hospital of Heilongjiang University of traditional Chinese Medicine from November 2014 to November 2015. According to the exclusion criteria, the AECOPD patients who were diagnosed and treated by Professor Liu Jianqiu. A total of 85 prescriptions were included. The original database of 85 prescriptions was established. Microsoft Excel 2003 software was used to analyze the frequency of drug use from the aspects of frequency, quality and efficacy, and the SPSS19.0 software was used to cluster analysis of the frequency greater than or equal to 20. Results: in 85 prescriptions, 104 herbs were involved, and 1173 frequencies were found. Among them, there were 11 kinds of medicine with frequency 鈮,
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