本文選題：失眠 + 肝郁血虛型��； 參考：《遼寧中醫(yī)藥大學(xué)》2017年碩士論文

【摘要】：目的:通過收集導(dǎo)師門診臨證病例資料,將其所用方劑,按用藥頻次,中藥四氣、五味、歸經(jīng)、類別等進(jìn)行統(tǒng)計,并且對使用頻率較高的藥物進(jìn)行聚類分析,研究陳民教授治療肝郁血虛型失眠用藥規(guī)律,為臨床治療該病提供思路與方法。材料與方法:收集2015年7月1日至2016年12月30日來遼寧中醫(yī)藥大學(xué)附屬醫(yī)院老年病科門診,由陳民教授診治的患者,按照納入和排除標(biāo)準(zhǔn)篩選而得的門診病例。采集性別、年齡、方藥等信息,統(tǒng)一錄入Excel表以建立數(shù)據(jù)庫,運(yùn)用Excel表格及應(yīng)用SPSS22.0統(tǒng)計分析軟件分析處方用藥頻次和使用頻率,選定25%以上作為藥物使用的高頻率,并對這些藥物的藥性、藥味經(jīng)、功效進(jìn)行分類,聚類成方。結(jié)果:按中醫(yī)四氣、五味、歸經(jīng)、藥類統(tǒng)計用藥頻次,比較其頻次高低。一.1.依據(jù)納入的120例病例,病例中應(yīng)用中藥共104味,使用頻率大于45%共12味,分別為柴胡、黃芩、白術(shù)、白芍、當(dāng)歸、陳皮、川芎、合歡花、茯苓、百合、甘草、酸棗仁。2.四氣:溫性藥頻次最多,其余依次為平性,寒性,涼、熱性使用較少。3.五味:甘味藥應(yīng)用最多,頻次為1283次,其余依次為苦味,辛味,酸味,其余藥味應(yīng)用較少。4.歸經(jīng):脾經(jīng)藥物應(yīng)用1187次,次數(shù)最多,其余依次為肝經(jīng)藥,肺經(jīng)藥,心經(jīng)藥。5.藥類:常用藥類第一位為補(bǔ)虛藥,第二位為解表藥,第三位為安神藥,清熱藥位排第四,第五位為活血化瘀藥,第六位為利水滲濕藥,第七位為理氣藥。二.聚類成方:通過SPSS22.0分析用藥頻率大于25%的藥物,得到兩個聚類方。結(jié)論:1.恩師在治療肝郁血虛型失眠時,以疏肝解郁,養(yǎng)血寧神為主要治法,具體用方常以逍遙散加減合酸棗仁湯加減治療。2.本病易出現(xiàn)肝盛乘脾,氣郁化火,虛火擾心,氣郁血瘀等病理變化,治以平肝柔肝,補(bǔ)中理氣,滋陰泄火,清心除煩,活血化瘀之法。3.通過分析得到的統(tǒng)計數(shù)據(jù)與聚類方劑,研究恩師的治法與用藥規(guī)律,為治療本病提供一定的參考意義。
[Abstract]:Objective: to collect the data of clinical cases of mentors' outpatient clinic and analyze the prescriptions according to the frequency of medication, the four qi of Chinese medicine, the five flavors, the meridians, the categories and so on, and cluster analysis of the drugs with high frequency of use. To study the rule of professor Chen Min in treating insomnia with liver depression and blood deficiency, and to provide ideas and methods for clinical treatment of this disease. Materials and methods: from July 1, 2015 to December 30, 2016, the outpatients of geriatric department of affiliated hospital of Liaoning University of traditional Chinese Medicine were collected and selected according to the criteria of inclusion and exclusion. The data of gender, age, prescription medicine were collected, and the Excel table was entered to establish the database. The frequency and frequency of prescription drug use were analyzed by Excel table and SPSS22.0 statistical analysis software. More than 25% was selected as the high frequency of drug use. The medicinal properties, taste and efficacy of these drugs are classified and clustered into prescriptions. Results: according to TCM four qi, five flavors, return to the meridian, medicine statistics frequency, compare its frequency. One. According to 120 cases, 104 kinds of Chinese medicine were used in the cases, the frequency of which was more than 45%, 12 were Radix Bupleurum, Radix Scutellariae, Atractylodes macrocephala, Radix Paeoniae Alba, Radix angelica sinensis, Chen Pei, Ligusticum chuanxiong, Huanhuan, Poria cocos, Lily, Glycyrrhiza, Zizyphus jujube. Four gas: the frequency of warm drugs is the most, the rest is flat, cold, cool, heat use less. 3. Five flavors: sweet flavor medicine is the most frequently used, frequency is 1283, the rest is bitter taste, symplectic taste, sour taste, the other taste application is less. 4. Gui Jing: spleen meridian drugs 1187 times, the most times, the rest followed by liver medicine, lung medicine, heart meridian drug .5. Drugs: the first is tonifying medicine, the second is antidote, the third is antipsychotic, the fourth is heat clearing drug, the fifth is promoting blood circulation and removing blood stasis, the sixth is promoting water and infiltrating dampness, and the seventh is regulating qi. II. Cluster prescription: two clusters were obtained by SPSS22.0 analysis of drugs whose frequency was more than 25%. Conclusion 1. In treating insomnia of stagnation of liver and blood deficiency, the main treatment method is to soothe the liver and relieve the depression, nourish the blood and Ningshen as the main treatment method, and the specific prescription is often treated with Xiaoyao San and Suanzaoren decoction. 2. This disease is prone to liver Sheng by spleen, Qi stagnation fire, fire disturbance heart, Qi stagnation and blood stasis and other pathological changes, to calm the liver and liver, tonify Qi, nourish yin and vent fire, clear the heart to remove annoyance, blood stasis method. 3. Through the analysis of the statistical data and cluster prescription, this paper studies the law of treatment and medication of Enshi University, which provides some reference significance for the treatment of this disease.
【學(xué)位授予單位】：遼寧中醫(yī)藥大學(xué)
【學(xué)位級別】：碩士
【學(xué)位授予年份】：2017
【分類號】：R249;R256.23

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