本文選題：通竅回聰湯 + 突發(fā)性耳聾　； 參考：《福建中醫(yī)藥大學》2016年碩士論文

【摘要】：目的：觀察通竅回聰湯聯(lián)合常規(guī)治療對氣滯血瘀型突發(fā)性耳聾(sudden hearing loss, SHL)的臨床療效。 探討中醫(yī)藥在突發(fā)性耳聾治療中促進聽力恢復、減輕伴隨癥狀、縮短療程中的作用及其相關(guān)機理,以尋找突發(fā)性耳聾較為理想的中醫(yī)治療方法及方藥,為臨床治療突發(fā)性耳聾提供更好的中醫(yī)理論參考及有效治療原則。方法:觀察突發(fā)性耳聾的住院患者共60例,隨機分為治療組和對照組,每組各30例。治療組采用通竅回聰湯加減聯(lián)合常規(guī)治療,對照組采用常規(guī)治療,共治療2周。利用純音聽閾測定及聽性腦干反應測試檢查來評判應用通竅回聰湯聯(lián)合常規(guī)治療與單純常規(guī)治療前后的療效差異,并記錄兩組治療前、治療后耳鳴改善情況,按照療效評定標準,對數(shù)據(jù)進行統(tǒng)計分析以評價中藥聯(lián)合常規(guī)治療的療效。結(jié)果:1、治療1周后,對比兩組的聽力提高程度,治療組有效率61.29%,對照組有效率56.25%,經(jīng)統(tǒng)計學比較兩組有效率P=0.0200.05,具有統(tǒng)計學差異,治療組優(yōu)于對照組。2、治療2周后,兩組聽力情況比較,治療組有效率77.42%,對照組有效率71.88%經(jīng)統(tǒng)計學觀察兩組有效率P=0.0340.05,具有統(tǒng)計學差異,治療組優(yōu)于對照組。3、治療2周后比較兩組治療前后平均氣導聽閡差值,治療組平均差值18.27± 8.55dBHL,對照組前后平均差值15.09±7.37dBHL,經(jīng)統(tǒng)計學觀察兩組有效率P0.05,具有統(tǒng)計學差異,治療組提升幅度優(yōu)于對照組。4、兩組患者治療前后耳鳴等級分布情況比較,差異均有統(tǒng)計學意義(Z=-3.162,P=0.03 10.05),即兩種治療方法在減輕耳鳴癥狀均有效,治療組明顯優(yōu)于對照組。5、治療結(jié)束后,兩組患者均無特殊不適,查肝功、腎功未見明顯異常,表明通竅回聰湯無肝腎損害。結(jié)論1、對突發(fā)性耳聾造成的聽力下降及耳鳴,兩組藥物均有一定的作用,通竅回聰湯聯(lián)合常規(guī)治療優(yōu)于常規(guī)治療方案。2、通竅回聰湯是治療突發(fā)性耳聾安全、有效的方劑,值得臨床推廣。
[Abstract]:Objective: to observe the clinical effect of Tongqiao Huicong decoction combined with routine treatment on sudden deafness due to Qi stagnation and blood stasis. To explore the effect of traditional Chinese medicine (TCM) in the treatment of sudden deafness, to promote the recovery of hearing, to alleviate the accompanying symptoms, to shorten the course of treatment and its related mechanism, in order to find the ideal TCM treatment method and prescription for sudden deafness. For clinical treatment of sudden deafness to provide a better theoretical reference and effective treatment principles. Methods: 60 patients with sudden deafness were randomly divided into treatment group and control group with 30 cases in each group. The treatment group was treated with Tongqiao Huicong decoction combined with conventional therapy, while the control group was treated with conventional therapy for 2 weeks. Pure tone hearing threshold test and auditory brainstem response test were used to evaluate the curative effect of Tongqiao Huicong decoction combined with conventional treatment and simple routine treatment, and to record the improvement of tinnitus before and after treatment in the two groups. According to the evaluation criteria, the data were statistically analyzed to evaluate the efficacy of traditional Chinese medicine combined with conventional therapy. Results one week after treatment, the hearing improvement of the two groups was compared. The effective rate of the treatment group was 61.29 and that of the control group was 56.25.The effective rate of the two groups was 0.0200.05. there was statistical difference between the two groups. The treatment group was better than the control group, and the treatment group was better than the control group. After 2 weeks of treatment, the effective rate of the treatment group was better than that of the control group. The effective rate of the treatment group was 77.42%, and that of the control group was 71.88%. The effective rate of the two groups was 0.0340.05. there was statistical difference between the two groups. The treatment group was superior to the control group (.3.) after 2 weeks of treatment, the difference of the average air-conduction hearing barrier between the two groups before and after treatment was compared. The average difference was 18.27 鹵8.55dBHLin the treatment group and 15.09 鹵7.37dBHLin the control group. The effective rate of the two groups was significantly higher than that of the control group (P0.05). The improvement range of the treatment group was better than that of the control group (.4). The distribution of tinnitus grade before and after treatment was compared between the two groups. The difference was statistically significant. The two treatment methods were effective in alleviating tinnitus symptoms, and the treatment group was superior to the control group. After the treatment, there was no special discomfort in both groups, and the liver function and renal function were not abnormal. It showed that Tongqiao Huicong decoction had no liver and kidney damage. Conclusion 1. Both drugs have certain effects on hearing loss and tinnitus caused by sudden deafness. Tongqiao Huicong decoction combined with routine treatment is superior to routine treatment plan. Tongqiao Huicong decoction is a safe and effective prescription for treating sudden deafness. It is worth popularizing in clinic.
【學位授予單位】：福建中醫(yī)藥大學
【學位級別】：碩士
【學位授予年份】：2016
【分類號】：R276.1

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