發(fā)布時(shí)間：2018-05-07 09:00

  本文選題：糖尿病腎�、笃� + 高尿酸血癥��； 參考：《新疆醫(yī)科大學(xué)》2016年碩士論文

【摘要】：目的:觀察以通腑泄?jié)釣榉ǖ奶悄I灌腸方治療2型糖尿病腎病(Type 2 diabetic nephropathy,T2DN)合并無癥狀高尿酸血癥(Hyperuricemia,HUA)的臨床療效。方法:把入組的60名2型糖尿病腎�、笃诤喜o癥狀高尿酸血癥患者隨機(jī)分成2組,治療組采用西醫(yī)療法(采用低蛋白低嘌呤飲食,每日飲水量保持在2000ml以上,口服降糖藥物或(和)胰島素皮下注射控制血糖,并配合血管緊張素受體拮抗劑(Angiotensin Receptor Blocker,ARB)纈沙坦80mg,日一次,口服;合并高血壓者,配合鈣離子拮抗劑),在此基礎(chǔ)上加用糖腎灌腸方(中藥灌腸藥液組成:生大黃30g、煅牡蠣50g、澤瀉30g、丹參15g、槐花30g、附子15g、黃芩30g。灌腸方法:將藥濃煎取汁,溫度為37℃-38℃,一次性輸液管插入肛門20-30cm,每次灌入250ml,保留30min以上,每晚1次),對(duì)照組采用單純西醫(yī)療法(采用低蛋白低嘌呤飲食,每日飲水量保持在2000ml以上�？诜堤撬幬锘�(和)胰島素皮下注射控制血糖,并配合ARB藥物纈沙坦80mg,日一次,口服;合并高血壓者,配合鈣離子拮抗劑),治療療程為20天,在治療前后分別對(duì)尿微量蛋白、尿酸、空腹血糖、甘油三酯、總膽固醇等指標(biāo)進(jìn)行檢測(cè)。結(jié)果:(1)本試驗(yàn)納入分析共60例,治療組30例,對(duì)照組30例;(2)指標(biāo)比較:治療組在改善尿微量白蛋白、尿酸、空腹血糖方面明顯優(yōu)于對(duì)照組(P0.05),治療組在改善甘油三酯、總膽固醇與對(duì)照組療效相當(dāng)(P0.05)。結(jié)論:糖腎灌腸方在對(duì)糖尿病腎�、笃诤喜o癥狀高尿酸血癥患者的治療中,對(duì)減少尿微量白蛋白,降低尿酸、空腹血糖方面的治療優(yōu)于單純西醫(yī)治療組。在治療糖尿病腎�、笃诩案吣蛩嵫Y中安全有效,值得臨床推廣。
[Abstract]:Objective: to observe the clinical effect of Tangshen enema decoction (TXD) in treating type 2 diabetic nephropathy (T2DN) with asymptomatic hyperuricemia. Methods: sixty patients with type 2 diabetic nephropathy and asymptomatic hyperuricemia were randomly divided into two groups. The treatment group was treated with western medicine (low protein and low purine diet, the daily water intake was above 2000ml). Taking hypoglycemic drugs or / and insulin subcutaneously to control blood glucose, combined with Angiotensin Receptor Blocker ARB80 mg, once a day, in patients with hypertension, In combination with calcium antagonist, Tang Shen enema prescription was added (composition of traditional Chinese medicine enema liquid: raw rhubarb 30g, calcined oyster 50g, alisma sinensis 30g, salvia miltiorrhiza 15g, Sophorae japonica 30g, aconite 15g, baicalin 30g. Enema method: extract juice by concentrated decoction, temperature was 37 鈩，

本文編號(hào)：1856296