本文選題：健脾疏肝湯 + 肝郁脾虛證��； 參考：《湖南中醫(yī)藥大學(xué)》2016年碩士論文

【摘要】：研究目的本研究的主要目的在于觀察健脾疏肝湯治療肛門直腸神經(jīng)官能癥(肝郁脾虛證)的臨床療效,從而初步評(píng)價(jià)健脾疏肝湯治療此病的有效性,為臨床治療此病提供一種可行有效的治療方法。研究方法選取符合此病診斷標(biāo)準(zhǔn)的60例病例,采用隨機(jī)對照臨床實(shí)驗(yàn)設(shè)計(jì),分為治療組、對照組,每組30例。治療組予以健脾疏肝湯內(nèi)服,每日一劑,分早晚溫服,對照組予以逍遙散內(nèi)服,每日一劑,分早晚溫服。根據(jù)患者實(shí)際情況,觀察并記錄兩組患者治療前、后的焦慮傾向、SF量表及治療前、后的中醫(yī)癥狀量化積分,并做統(tǒng)計(jì)學(xué)處理分析結(jié)果。研究結(jié)果1.治療組與對照組治療前隨機(jī)因素(性別、年齡、病程)無明顯差異(P0.05)。2.漢密爾頓焦慮量表(HAMA):兩組患者中,輕度、中度焦慮的患者所占比例較大,其中治療組輕中度焦慮患者為80%,對照組輕中度焦慮患者為86.6%。兩組P0.05,具有統(tǒng)計(jì)學(xué)意義。2.SF--36量表:兩組治療前比較,無顯著性差異(P0.05)。治療組前后、對照組前后的八個(gè)生理維度比較有統(tǒng)計(jì)學(xué)差異(P0.05)。兩組治療后比較,其中精力組、社會(huì)功能組P0.05,無統(tǒng)計(jì)學(xué)差異;生理職能組、軀體疼痛組、精神健康、一般健康狀況組、情感職能組,P均小于0.05,均具有統(tǒng)計(jì)學(xué)差異。3.中醫(yī)癥候積分:兩組患者治療前比較,P0.05,故兩組患者治療前不存在統(tǒng)計(jì)學(xué)差異;兩組患者治療后半月、治療后1月組間比較,P0.05,具有統(tǒng)計(jì)學(xué)差異;兩組患者治療前與治療后半月組內(nèi)比較,兩組P0.01(P=0.000),治療前后存在顯著差異。治療組治療后半月與治療后1月,P0.05有統(tǒng)計(jì)學(xué)差異,對照組治療后半月與治療后1月,P0.05,不具有統(tǒng)計(jì)學(xué)差異。4.兩組患者治療期間均未見明顯毒副作用、不良反應(yīng)及過敏現(xiàn)象。結(jié)論1.罹患肛門直腸神經(jīng)官能癥的患者,很大一部分伴有焦慮傾向,此病的發(fā)生與精神活動(dòng)息息相關(guān)。2.對于肝郁脾虛證的肛門直腸神經(jīng)官能癥的患者,健脾疏肝湯能有效改善臨床癥狀,提高患者生活質(zhì)量,比逍遙散臨床療效更明顯。
[Abstract]:Objective to observe the clinical efficacy of Jianpi Shugan decoction in the treatment of anorectal neurosis (liver depression and spleen deficiency syndrome), and to evaluate the effectiveness of Jianpi Shugan decoction in the treatment of this disease. To provide a feasible and effective treatment for this disease. Methods Sixty patients who met the diagnostic criteria were divided into treatment group and control group with 30 cases in each group. The treatment group was taken orally with Jianpi Shugan decoction, one dose per day, divided into morning and evening warm clothes, while the control group was given Xiaoyao Powder, one dose daily, one daily, and one morning and evening warm. According to the actual situation of the patients, we observed and recorded the anxiety tendency of the two groups before and after treatment with SF scale and the quantitative scores of TCM symptoms before and after treatment, and made statistical analysis results. Results 1. There was no significant difference in random factors (sex, age, course of disease) between the treatment group and the control group before treatment (P 0.05). Hamilton anxiety scale (Hamilton anxiety scale): the proportion of mild and moderate anxiety was higher in the two groups, 80 in the treatment group and 86.6 in the control group. 2. SF-36 scale: there was no significant difference before treatment between the two groups (P 0.05). Before and after the treatment group, the control group before and after the comparison of the eight physiological dimensions there was a statistical difference (P 0.05). After treatment, there was no significant difference between the two groups (P 0.05), physical function group, somatic pain group, mental health group, general health group, affective function group, P < 0.05, with statistical difference. TCM symptom score: two groups of patients before treatment compared with P0.05, so there is no statistical difference between the two groups before treatment, two groups of patients after treatment half a month, one month after treatment, there is a statistical difference between the two groups. There was a significant difference between the two groups before and after treatment. There was significant difference in the treatment group between the latter half month and the first month after treatment (P0.05), while in the control group there was no statistical difference between the latter half month and one month after treatment (P0.05). 4. There were no obvious side effects, side effects and allergies in both groups. Conclusion 1. A large proportion of patients with anorectal neurosis are associated with anxiety, which is closely related to mental activity. For patients with anorectal neurosis due to liver stagnation and spleen deficiency, Jianpi Shugan decoction can effectively improve clinical symptoms and improve the quality of life of patients, which is more effective than Xiaoyao Powder.
【學(xué)位授予單位】：湖南中醫(yī)藥大學(xué)
【學(xué)位級(jí)別】：碩士
【學(xué)位授予年份】：2016
【分類號(hào)】：R266

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