調(diào)和營衛(wèi)法治療慢性心力衰竭痰飲阻肺證的臨床研究
本文選題:調(diào)和營衛(wèi) + 慢性心力衰竭 ; 參考:《山東中醫(yī)藥大學》2016年碩士論文
【摘要】:目的:觀察調(diào)和營衛(wèi)法治療慢性心力衰竭痰飲阻肺證方面的臨床療效,探討其病因病機以及治法方藥。方法:觀察60例慢性心力衰竭(NYHA分級:II-III級)患者,隨機分為對照組和試驗組,每組各30例。對照組給予三子養(yǎng)親湯、葶藶大棗瀉肺湯,試驗組在對照組治療基礎(chǔ)上加用調(diào)和營衛(wèi)的桂枝湯,兩組均進行西醫(yī)常規(guī)治療,服藥4周。觀察調(diào)和營衛(wèi)的桂枝湯對慢性心力衰竭患者左心室射血分數(shù)(LVEF)、N末端B型腦鈉肽前體(NT-proBNP)、同型半胱氨酸(HCY)、心率變異性(HRV)、地高辛及利尿劑停減率、Lee氏心力衰竭癥狀積分、中醫(yī)癥狀療效積分的影響。結(jié)果:治療4周后,兩組患者Lee氏心力衰竭癥狀積分、中醫(yī)癥狀療效積分均有明顯改善,試驗組總有效率優(yōu)于對照組,比較具有統(tǒng)計學意義(P0.05)。試驗組加用調(diào)和營衛(wèi)方劑后,能明顯提高心功能及心室射血分數(shù)指標,降低腦鈉肽、同型半胱氨酸水平,改善心率變異性,提高地高辛及利尿劑停減率,試驗組療效優(yōu)于對照組,比較具有統(tǒng)計學意義(P0.05)。結(jié)論:調(diào)和營衛(wèi)法治療慢性心力衰竭痰飲阻肺證臨床療效確切,能有效改善患者心力衰竭臨床癥狀及預(yù)后水平,提高患者生存質(zhì)量。
[Abstract]:Objective: to observe the clinical effect of tonifying Ying Wei method on phlegm and phlegm blocking lung syndrome in chronic heart failure, and to explore its etiology, pathogenesis and prescription. Methods: 60 patients with chronic heart failure were randomly divided into two groups: control group and experimental group, with 30 cases in each group. The control group was treated with Sanzi Yangfu decoction and the Tinglida Zizao Xiefe decoction. The experimental group was treated with Guizhi decoction combined with that of the control group. The two groups were treated with routine western medicine for 4 weeks. To observe the effects of Guizhi decoction on left ventricular ejection fraction (LVEF) in patients with chronic heart failure (CHF), NT-proBNPN, homocysteine (HCY), heart rate variability (HRV), digoxin (digoxin) and diuretic withdrawal rate (DDR) and the symptom score of Lee's heart failure. The influence of TCM symptom curative effect integral. Results: after 4 weeks of treatment, the symptom score of Lee's heart failure and the score of TCM symptom curative effect in both groups were obviously improved. The total effective rate in the experimental group was better than that in the control group, and the comparison was statistically significant (P 0.05). In the experimental group, the heart function and ventricular ejection fraction were significantly increased, the levels of brain natriuretic peptide and homocysteine were decreased, heart rate variability was improved, digoxin and diuretic stopped reduction rate were increased. The curative effect of the test group was better than that of the control group, and the comparison had statistical significance (P 0.05). Conclusion: it is effective to treat chronic heart failure with phlegm and phlegm blocking lung syndrome. It can effectively improve the clinical symptoms and prognosis of patients with heart failure and improve the quality of life of patients with chronic heart failure.
【學位授予單位】:山東中醫(yī)藥大學
【學位級別】:碩士
【學位授予年份】:2016
【分類號】:R259
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