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潰瘍性結(jié)腸炎內(nèi)鏡下表現(xiàn)與中醫(yī)證型的相關(guān)性研究

發(fā)布時間:2018-04-23 05:07

  本文選題:潰瘍性結(jié)腸炎 + 腸鏡。 參考:《山東中醫(yī)藥大學(xué)》2016年碩士論文


【摘要】:研究目的:探討潰瘍性結(jié)腸炎的不同中醫(yī)證型與內(nèi)鏡下黏膜像的相關(guān)性,總結(jié)內(nèi)鏡下的辨證規(guī)律,以加強(qiáng)中醫(yī)辨證的客觀化,為潰瘍性結(jié)腸炎的標(biāo)準(zhǔn)化治療提供一定的理論依據(jù)。研究方法:1.收集潰瘍性結(jié)腸炎患者的基本信息及相關(guān)臨床資料,嚴(yán)格按照納入標(biāo)準(zhǔn)及排除標(biāo)準(zhǔn)篩選出53例病例,閱讀相關(guān)文獻(xiàn)資料,結(jié)合本課題的研究思路設(shè)計(jì)出相應(yīng)表格。2.觀察53例患者結(jié)腸鏡下黏膜像的特點(diǎn),以及患者的相關(guān)臨床資料,進(jìn)行數(shù)據(jù)錄入。3.采用SPSS17.0統(tǒng)計(jì)軟件處理分析,得出結(jié)論。研究結(jié)果:1.本研究收集臨床病例共53例,平均年齡為44.51±14.46歲,男女之比為2.1:1,且84.9%患者無吸煙史。本病最常見的誘發(fā)因素為飲食因素,占49.1%,其次為過度勞累,占35.8%,兩者合計(jì)超過三分之二。2.患者常見臨床癥狀前十位分別為:腹瀉、腹部隱痛、黏液膿血便為主、納差、黏液便為主、眠差、里急后重、肢體倦怠、肛門下墜、腸鳴等。3.患者結(jié)腸鏡下常見黏膜像特點(diǎn)分布為:充血糜爛、淺潰瘍形成、血管紋理不清、黏膜粗糙不平、覆著膿苔、假息肉形成,出現(xiàn)頻率較少的癥狀為:蠕動不規(guī)律、結(jié)腸袋消失、滲血及黏膜橋形成。4.兩種中醫(yī)證型與疾病的嚴(yán)重程度、病變范圍無統(tǒng)計(jì)學(xué)意義,而與腸黏膜表面是否有膿苔覆著、是否有滲血及假息肉的存在及舌質(zhì)、舌苔之間有明顯的相關(guān)性。大腸濕熱證患者腸黏膜表面易有膿苔覆著,黏膜易有滲血,而脾虛濕蘊(yùn)證患者結(jié)腸鏡下易形成假息肉。紅舌黃膩苔在大腸濕熱證多見,而淡紅舌白膩苔在脾虛濕蘊(yùn)證多見。研究結(jié)論:潰瘍性結(jié)腸炎多發(fā)生于中青年男性,其兩種中醫(yī)證型與結(jié)腸鏡下黏膜表面是否有膿苔覆著、是否有滲血、假息肉的存在及舌質(zhì)、舌苔之間有明顯的相關(guān)性。
[Abstract]:Objective: to explore the relationship between different TCM syndromes of ulcerative colitis and mucosal image under endoscope, and summarize the law of syndrome differentiation under endoscope, so as to strengthen the objectivity of TCM syndrome differentiation. To provide a theoretical basis for standardized treatment of ulcerative colitis. Research method: 1. Collect the basic information and related clinical data of ulcerative colitis patients, select 53 cases strictly according to the inclusion criteria and exclusion criteria, read the relevant literature, and design the corresponding form. 2. The characteristics of mucosal images under colonoscopy and the clinical data of 53 patients were observed, and the data were inputted. 3. 3. SPSS17.0 statistical software is used to deal with the analysis and draw a conclusion. The result of the study was: 1. In this study, 53 clinical cases were collected, the average age was 44.51 鹵14.46 years old, the ratio of male to female was 2.1: 1, and 84.9% of the patients had no smoking history. The most common inducing factor of the disease was diet, accounting for 49. 1%, followed by overwork, accounting for 35. 8%. The total of both was more than 2/3. 2. The first ten common clinical symptoms of the patients were diarrhea, abdominal pain, mucus purulent blood stool, anorexia, mucus stool, sleep loss, restlessness, limb burnout, anus fall, bowel ringing, etc. The features of common mucosal images under colonoscopy were hyperemia and erosion, shallow ulcer formation, unclear vascular texture, rough mucous membrane, abscess moss and pseudopolypus formation. The symptoms with less frequency were irregular peristalsis and disappearance of colonic bag. Blood leakage and mucosal bridge formation. There was no statistical significance between the two types of TCM syndromes and the severity of the disease, but there was a significant correlation with the presence of purulent fur on the surface of intestinal mucosa, the presence of oozing blood and false polyps and the tongue quality, and the tongue coating. The mucous membrane of patients with large intestine damp-heat syndrome is prone to be covered with pus and mucous membrane is easy to ooze blood, while spleen deficiency and dampness accumulation syndrome patients are prone to form pseudopolyps under colonoscopy. Yellow greasy fur of red tongue is more common in damp-heat syndrome of large intestine, while white greasy fur of light red tongue is more common in dampness accumulation syndrome of spleen deficiency. Conclusion: ulcerative colitis mostly occurs in young and middle-aged men. There is a significant correlation between the two TCM syndromes and whether the mucous membrane is covered with pus, whether there is blood leakage, the existence of pseudopolyps, tongue quality and tongue coating under colonoscopy.
【學(xué)位授予單位】:山東中醫(yī)藥大學(xué)
【學(xué)位級別】:碩士
【學(xué)位授予年份】:2016
【分類號】:R259

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