本文選題：四金湯 + 慢性膽囊炎　； 參考：《廣西中醫(yī)藥大學(xué)》2017年碩士論文

【摘要】：目的:觀察四金湯對氣滯血瘀證慢性膽囊炎患者的臨床療效,為其治療氣滯血瘀證慢性膽囊炎提供依據(jù)。方法:將符合納入標(biāo)準(zhǔn)的60例氣滯血瘀證慢性膽囊炎患者隨機(jī)分為對照組、治療組,每組30例;對照組給予熊去氧膽酸膠囊治療,治療組在熊去氧膽酸膠囊治療上加予四金湯治療,治療4周,觀察兩組治療后的有效率、兩組患者治療前后癥狀積分以及膽囊彩超改善情況的變化。結(jié)果:(1)治療組的總有效率為89.66%,對照組的總有效率75.86%,治療組的總有效率優(yōu)于對照組,差異具有統(tǒng)計學(xué)意義(P0.05);(2)治療組中醫(yī)證候有效率為93.10%;對照組中醫(yī)證候有效率為79.31%,治療組的中醫(yī)證候有效率優(yōu)于對照組,差異具有統(tǒng)計學(xué)意義(P0.05);(3)治療后,治療組的右上腹疼痛或不適感評分為1.06±0.45分,對照組的右上腹疼痛或不適感評分為1.52±0.59分,治療組的右上腹疼痛或不適感評分低于對照組,差異具有統(tǒng)計學(xué)意義(P0.05);治療后,治療組的惡心噯氣評分為0.84±0.25分,對照組的惡心噯氣評分為1.48±0.31分,治療組的的惡心噯氣評分低于對照組,差異具有統(tǒng)計學(xué)意義(P0.05);治療后,治療組進(jìn)油膩食物后腹脹評分為1.03±0.33分,對照組進(jìn)油膩食物后腹脹評分為1.87±0.42分,治療組的進(jìn)油膩食物后腹脹評分低于對照組,差異具有統(tǒng)計學(xué)意義(P0.05);治療后,治療組膽囊區(qū)壓痛或叩擊痛評分為0.53±0.12分,對照組膽囊區(qū)壓痛或叩擊痛評分為1.07±0.23分,治療組的膽囊區(qū)壓痛或叩擊痛評分低于對照組,差異具有統(tǒng)計學(xué)意義(P0.05);治療后,治療組口苦咽干評分為0.54±0.20分,對照組口苦咽干評分為1.62±0.42分,治療組的口苦咽干評分低于對照組,差異具有統(tǒng)計學(xué)意義(P0.05);治療后,治療組痛引肩背感評分為0.54±0.32分,對照組痛引肩背感評分為0.91±0.48分,治療組的痛引肩背感評分低于對照組,差異具有統(tǒng)計學(xué)意義(P0.05);治療后,治療組納呆食少評分為1.54±0.35分,對照組納呆食少評分為1.88±0.61分,治療組的納呆食少評分低于對照組,差異具有統(tǒng)計學(xué)意義(P0.05);(4)治療組膽囊彩超有效率為86.21%,對照組膽囊彩超有效率72.41%,治療組的膽囊彩超有效率高于對照組的有效率,差異具有統(tǒng)計學(xué)意義(P0.05)。結(jié)論:(1)四金湯能夠有效改善氣滯血瘀證慢性膽囊炎患者的臨床癥狀及體征。(2)四金湯能夠明顯改善氣滯血瘀證慢性膽囊炎彩超影像學(xué)表現(xiàn)。
[Abstract]:Objective: to observe the clinical effect of Sijin decoction on chronic cholecystitis of qi stagnation and blood stasis syndrome, and to provide evidence for the treatment of chronic cholecystitis with qi stagnation and blood stasis syndrome.Methods: sixty patients with chronic cholecystitis of Qi stagnation and Blood stasis Syndrome were randomly divided into control group (n = 30) and control group (n = 30), which were treated with ursodeoxycholic acid capsule.The treatment group was treated with Sijin decoction on ursodeoxycholic acid capsule for 4 weeks. The effective rate of the two groups after treatment and the change of symptom score and the improvement of gallbladder color ultrasound before and after treatment were observed.Results the total effective rate of the treatment group was 89.66, the total effective rate of the control group was 75.86, the total effective rate of the treatment group was better than that of the control group.The effective rate of TCM syndrome in the treatment group was 93.10 and that in the control group was 79.31. The effective rate of TCM syndrome in the treatment group was better than that in the control group, and the difference was statistically significant after treatment.The scores of right epigastric pain or discomfort were 1.06 鹵0.45 in the treatment group and 1.52 鹵0.59 in the control group. The scores of right epigastric pain or discomfort in the treatment group were lower than those in the control group (P 0.05).The nausea belching score of the treatment group was 0.84 鹵0.25, and that of the control group was 1.48 鹵0.31, the score of the treatment group was lower than that of the control group (P 0.05), the abdominal distension score of the treatment group was 1.03 鹵0.33 after greasy food intake.The abdominal distension score of the control group was 1.87 鹵0.42 after greasy food intake, the abdominal distension score of the treatment group was lower than that of the control group, the difference was statistically significant (P 0.05), and after treatment, the gallbladder tenderness or percussion pain score was 0.53 鹵0.12 in the treatment group.The score of gallbladder tenderness or percussion pain in the control group was 1.07 鹵0.23, the score of gallbladder tenderness or percussion pain in the treatment group was lower than that in the control group, the difference was statistically significant (P 0.05), and after treatment, the score of dry oropharynx was 0.54 鹵0.20 in the treatment group.The score of dry oropharynx in the control group was 1.62 鹵0.42, and the score in the treatment group was lower than that in the control group, the difference was statistically significant (P 0.05), after the treatment, the score of the pain leading shoulder back sensation in the treatment group was 0.54 鹵0.32, and that in the control group was 0.91 鹵0.48, and that in the treatment group was 0.91 鹵0.48, and that in the control group was 0.91 鹵0.48.The scores of pain and shoulder sensation in the treatment group were lower than those in the control group, the difference was statistically significant (P 0.05), after treatment, the scores of the patients in the treatment group were 1.54 鹵0.35, the scores of the patients in the control group were 1.88 鹵0.61. the scores of the patients in the treatment group were lower than those in the control group, and the scores of the patients in the treatment group were lower than those in the control group.The difference was statistically significant (P 0.05)) the effective rate of color Doppler ultrasound was 86.21 in the treatment group and 72.41 in the control group. The effective rate of the treatment group was higher than that of the control group, and the difference was statistically significant.Conclusion: 1) Sijin decoction can effectively improve the clinical symptoms and signs of chronic cholecystitis with qi stagnation and blood stasis syndrome) Sijin decoction can obviously improve the imaging manifestations of chronic cholecystitis with qi stagnation and blood stasis syndrome.
【學(xué)位授予單位】：廣西中醫(yī)藥大學(xué)
【學(xué)位級別】：碩士
【學(xué)位授予年份】：2017
【分類號】：R259

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