本文選題：強(qiáng)志散　切入點(diǎn)：小兒多發(fā)性抽動(dòng)癥　出處：《山東中醫(yī)藥大學(xué)》2016年碩士論文

【摘要】：目的:觀察強(qiáng)志散治療小兒多發(fā)性抽動(dòng)癥(腎志不足證)的臨床療效和對(duì)患兒自控能力的干預(yù)效應(yīng),驗(yàn)證腎藏志理論對(duì)治療本病的指導(dǎo)價(jià)值。方法:將符合納入標(biāo)準(zhǔn)的60例多發(fā)性抽動(dòng)癥患兒按1:1的比例隨機(jī)分為中藥組和西藥組,分別給予強(qiáng)志散免煎顆粒(中藥組)和鹽酸硫必利片(西藥組)口服治療。治療24周,隨訪24周。觀察兩組治療前后總療效、抽動(dòng)癥狀、中醫(yī)證候和自控能力的療效、不良反應(yīng)和安全性、遠(yuǎn)期療效。結(jié)果:1.兩組抽動(dòng)療效比較,中藥組和西藥組總有效率分別為90%、73.33%,減分率分別為(64.35±21.34)%和(49.89±22.90)%,中藥組治療效果優(yōu)于西藥組。2.兩組證候療效比較,中藥組和西藥組總有效率分別為93.33%、76.67%,減分率分別為(60.82±16.62)%和(42.19±15.26)%,中藥組治療效果優(yōu)于西藥組。3.兩組自控能力改善情況比較,中藥組和西藥組總有效率分別為96.67%、76.67%,增分率分別為(65.70±15.10)%和(41.19±12.52)%,中藥組療效亦優(yōu)于西藥組。4.兩組在不良反應(yīng)率和復(fù)發(fā)率的比較,中藥組優(yōu)于西藥組;安全性比較無差別。結(jié)論:強(qiáng)志散治療小兒多發(fā)性抽動(dòng)癥(腎志不足證)的臨床療效及自控能力改善情況優(yōu)于鹽酸硫必利片。
[Abstract]:Objective: to observe the clinical effect of Qiangzhi Powder in the treatment of children with multiple tic syndrome (deficiency of renal records) and its intervention effect on the ability of self-control in children, and to verify the guiding value of the theory of Kidney Zang Zhi in the treatment of this disease.Methods: sixty children with multiple tic syndrome were randomly divided into Chinese medicine group and western medicine group according to the 1:1 ratio, and were given oral treatment of Qiang Zhi San Fan-Jian granule (Chinese medicine group) and tiapride hydrochloride tablet (western medicine group), respectively.The patients were followed up for 24 weeks.The total curative effect, twitch symptom, TCM syndromes and self-control ability, adverse reaction and safety, and long term curative effect were observed before and after treatment.The result is 1: 1.The total effective rates of TCM group and western medicine group were 90% and 73.33, respectively. The reduction rates were 64.35 鹵21.34% and 49.89 鹵22.90%, respectively. The curative effect of TCM group was better than that of western medicine group.The total effective rates of TCM group and western medicine group were 93.330.67 and 76.67, respectively. The reduction rates were 60.82 鹵16.62% and 42.19 鹵15.26%, respectively. The therapeutic effect of TCM group was better than that of western medicine group (.3).The total effective rate of the Chinese medicine group and the western medicine group were 96.67 and 76.67, respectively. The increase rates were 65.70 鹵15.10% and 41.19 鹵12.52%, respectively. The curative effect of the traditional Chinese medicine group was better than that of the western medicine group (.4).The adverse reaction rate and recurrence rate of the two groups were better than that of the western medicine group.Conclusion: Qiangzhi Powder is superior to Tiapride Hydrochloride tablets in the treatment of children with multiple tic syndrome.
【學(xué)位授予單位】：山東中醫(yī)藥大學(xué)
【學(xué)位級(jí)別】：碩士
【學(xué)位授予年份】：2016
【分類號(hào)】：R277.7

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