本文選題：膽汁反流性胃炎　切入點：膽胃郁熱　出處：《南京中醫(yī)藥大學(xué)》2017年碩士論文

【摘要】：目的:清熱化濕、利膽和胃法治療膽胃郁熱型膽汁反流性胃炎(BRG)的臨床療效觀察。方法:將60例膽胃郁熱型膽汁反流性胃炎病例隨機分為治療組和對照組,兩組各30例。病例收集自2016年4月至2016年12月期間來自江蘇省中醫(yī)院普內(nèi)科及脾胃病科門診和南京醫(yī)科大學(xué)第二附屬醫(yī)院消化科門診。治療組口服柴胡陷胸湯加減治療;對照組予枸櫞酸莫沙必利聯(lián)合鋁碳酸鎂片治療。觀察治療前后兩組中醫(yī)癥狀改善情況,計算各癥狀積分、總積分并建立數(shù)據(jù)庫,用SPSS19.0軟件統(tǒng)計、對比兩組治療療程(8周)后病情改善情況。結(jié)果:治療后,治療組治療BRG所有癥狀均有改善;對照組除舌苔黃膩無明顯改變外,其余主、次癥狀均有改善,兩組之間比較,主要癥狀胃胺灼熱疼痛、口苦而干的療效實驗組要優(yōu)于對照組,次要癥狀而言,在改善反酸、心煩易怒、舌苔、脈象上治療組的效果優(yōu)于對照組,在改善暖氣、不欲食上兩組的效果無差異;總體療效上,治療組治愈2例,顯效13例,有效13例,無效2例,30例痊愈率為6.6%,愈顯率為50%,總有效率93.3%;對照組治愈1例,顯效11例,有效16例,無效2例,30例痊愈率為3.3%,愈顯率為40%,總有效率93.3%;兩組愈顯率及有效率均無統(tǒng)計學(xué)差異,兩組療效均可,但在總體癥狀改善程度上,治療者優(yōu)于對照組。結(jié)論:運用清熱化濕、利膽和胃法治療膽胃郁熱型膽汁反流性胃炎(BRG)有較好的臨床療效。
[Abstract]:Objective: to observe the clinical effect of clearing heat and removing dampness and promoting gallbladder and stomach in treating bile reflux gastritis of choledochal stagnation heat type.Methods: 60 cases of bile reflux gastritis were randomly divided into treatment group and control group with 30 cases in each group.Cases were collected from the Department of General Medicine and the Department of spleen and stomach Diseases of Jiangsu Provincial Hospital of traditional Chinese Medicine from April 2016 to December 2016 and from the Department of Digestive Medicine of the second affiliated Hospital of Nanjing Medical University.The treatment group was treated with bupleurum sinensis decoction and the control group was treated with mosapride citrate combined with magnesium aluminum carbonate tablets.Observe the improvement of TCM symptoms before and after treatment, calculate the symptom integral, total score and establish the database, use SPSS19.0 software statistics, compare the two groups after the treatment course of 8 weeks.Results: after treatment, all symptoms of BRG in the treatment group were improved, except for the yellowish tongue coating, the other main and secondary symptoms were improved in the control group.The experimental group with bitter and dry mouth was better than the control group, and the treatment group was superior to the control group in improving regurgitation, irritability, tongue coating and pulse, but there was no difference between the two groups in improving heating and not wanting to eat.In the treatment group, 2 cases were cured, 13 cases were markedly effective, 13 cases were effective, 30 cases were ineffective, the cure rate was 6.6, the effective rate was 50% and the total effective rate was 93.3%, while in the control group, 1 case was cured, 11 cases were effective and 16 cases were effective.The cure rate was 3.3%, the effective rate was 40%, and the total effective rate was 93.3.The two groups had no statistical difference in the effective rate and the effective rate, but the treatment group was superior to the control group in the improvement degree of the overall symptoms.Conclusion: the method of clearing away heat and removing dampness and promoting gallbladder and stomach is effective in treating bile reflux gastritis of choledochal stagnation heat type.
【學(xué)位授予單位】：南京中醫(yī)藥大學(xué)
【學(xué)位級別】：碩士
【學(xué)位授予年份】：2017
【分類號】：R259

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本文編號：1718150