本文選題：膿毒癥　切入點(diǎn)：胃腸疾病　出處：《河北中醫(yī)》2017年03期

【摘要】：目的觀察膿毒癥胃腸功能障礙患者早期應(yīng)用大黃附子湯的臨床療效。方法將120例膿毒癥胃腸功能障礙患者隨機(jī)分為2組,對(duì)照組60例予基礎(chǔ)治療,治療組60例在對(duì)照組治療基礎(chǔ)上經(jīng)胃管注入大黃附子湯。2組均治療2周,評(píng)估患者治療72 h后急性胃腸損傷(AGI)分級(jí)情況;觀察2組治療前后胃腸功能障礙評(píng)分、急性生理功能和慢性健康狀況評(píng)分系統(tǒng)Ⅱ(APACHEⅡ)評(píng)分變化;比較2組治療后排便情況;比較2組臨床療效;觀察2組不良事件發(fā)生及死亡情況。結(jié)果 2組治療72 h后AGI分級(jí)情況比較差異有統(tǒng)計(jì)學(xué)意義(P0.05)。2組治療后胃腸功能障礙評(píng)分、APACHEⅡ評(píng)分均較本組治療前降低(P0.05),且治療組較對(duì)照組降低更明顯(P0.05)。與對(duì)照組比較,治療組第1次排便時(shí)間縮短,每日排便次數(shù)增多,不排便天數(shù)縮短,使用灌腸劑患者例數(shù)減少,比較差異均有統(tǒng)計(jì)學(xué)意義(P0.05)。治療組總有效率91.7%,對(duì)照組總有效率68.3%,2組比較差異有統(tǒng)計(jì)學(xué)意義(P0.05),治療組臨床療效優(yōu)于對(duì)照組。治療組多器官功能障礙綜合征(MODS)發(fā)生率18.3%,死亡率8.3%,對(duì)照組MODS發(fā)生率43.3%,死亡率35.0%,治療組不良事件發(fā)生率及死亡率均低于對(duì)照組(P0.05)。結(jié)論早期應(yīng)用大黃附子湯能明顯改善膿毒癥患者胃腸功能障礙,改善患者預(yù)后,值得臨床推廣。
[Abstract]:Objective to observe the clinical effect of rhubarb aconite decoction in patients with gastrointestinal dysfunction of sepsis.Methods 120 patients with gastrointestinal dysfunction of sepsis were randomly divided into two groups: the control group (n = 60) received basic treatment, the treatment group (n = 60) was treated with rhubarb aconite decoction (group .2) and the control group (n = 60).To evaluate the acute gastrointestinal injury (AGI) grading after 72 hours of treatment, to observe the scores of gastrointestinal dysfunction, acute physiological function and chronic health status 鈪，

本文編號(hào)：1699205