本文選題：腺樣體肥大　切入點：痰瘀互結(jié)型　出處：《黑龍江中醫(yī)藥大學》2017年碩士論文

【摘要】：目的:觀察清鼻止鼾湯治療兒童腺樣體肥大(痰瘀互結(jié)型)的臨床療效。方法:將160例腺樣體肥大患兒分為兩組,其中治療組120例,對照組40例,治療組治以活血祛瘀、化痰散結(jié),口服清鼻止鼾湯,一日2次;對照組口服鼻淵通竅顆粒并鼻腔吸入糠酸莫米松。療程均為3周。記錄2組用藥前后的癥狀體征,拍攝鼻咽部X線側(cè)位片或CT,計算A/N值,進行統(tǒng)計學分析。結(jié)果:治療組,因患兒服藥困難脫落4例,服藥中途病情嚴重加用其他藥物視為無效病例4例,完成記錄112例;對照組因病情嚴重加用其他藥物視為無效病例9例,完成記錄31例。治療組總有效率為96.55%,對照組總有效率為77.50%,差異有統(tǒng)計學意義,顯示在療效方面治療組明顯優(yōu)于對照組。對治療前后兩組中醫(yī)證候積分、中醫(yī)主要癥狀總積分進行比較,P值0.05,有統(tǒng)計學意義,治療組優(yōu)于對照組;對治療前后兩組中醫(yī)主要癥狀單項積分進行比較,其中鼻塞、睡眠打鼾、睡眠張口、睡眠鼻窒積分P值0.05,有統(tǒng)計學差異,治療組的癥狀改善明顯優(yōu)于對照組。對鼻咽部側(cè)位X線片A/N值這一客觀指標進行比較,P值0.05,有統(tǒng)計學差異,治療組優(yōu)于對照組。結(jié)論:1.清鼻止鼾湯治療兒童腺樣體肥大(痰瘀互結(jié)型)具有較好的臨床療效,明顯優(yōu)于口服鼻淵通竅顆粒并鼻腔吸入糠酸莫米松。2.清鼻止鼾湯能明顯改善痰瘀互結(jié)型腺樣體肥大患兒鼻塞、睡眠打鼾、睡眠張口等癥狀,且能明顯降低兒童鼻咽部X線側(cè)位片或CT的A/N值這一客觀指標。3.清鼻止鼾湯治療兒童腺樣體肥大(痰瘀互結(jié)型)具有良好的安全性,未見明顯不良反應(yīng)。
[Abstract]:Objective: to observe the clinical effect of Qingbizhisu decoction on children's adenoid hypertrophy (phlegm and blood stasis type). Methods: 160 children with adenoid hypertrophy were divided into two groups: 120 cases in treatment group and 40 cases in control group. Huatan Sanjie, oral Qingbeizhi decoction, 2 times a day; control group, oral Biyuan Tongqiao granule and nasal cavity inhaled momethasone furoate. The course of treatment was 3 weeks. The symptoms and signs of the two groups before and after treatment were recorded. Results: in the treatment group, 4 cases were lost because of difficulty in taking medicine, 4 cases were treated with other drugs and 4 cases were treated with other drugs, 112 cases were recorded. In the control group, the total effective rate was 96.55 and the total effective rate in the control group was 77.50, the difference was statistically significant. The results showed that the treatment group was obviously superior to the control group in curative effect. The score of TCM syndrome and the total integral of main symptoms of TCM were compared between the two groups before and after treatment (P = 0.05), which was statistically significant, and the treatment group was superior to the control group. The main symptoms of traditional Chinese medicine before and after treatment were compared between the two groups, including nasal congestion, sleep snoring, sleep mouth opening, sleep nasal smothering score P value 0.05, there was statistical difference. The improvement of symptoms in the treatment group was obviously better than that in the control group. Conclusion the treatment group is superior to the control group. Conclusion Qingbizhisu decoction has good clinical effect in treating children with adenoid hypertrophy (phlegm and blood stasis type). It was better than taking Biyuan Tongqiao granule and inhaling momethasone furoate in nasal cavity. Qingbeizu decoction could obviously improve the symptoms of nasal congestion, sleep snoring, sleep opening and so on in children with hypertrophy of sputum and blood stasis. The objective index of A- N value of lateral radiographs or CT of nasopharynx in children was significantly decreased. 3. Qingbeizhi decoction had good safety in treating children with adenoid hypertrophy (phlegm and blood stasis type), and no obvious adverse reactions were found in the treatment of children with adenoid hypertrophy (phlegm and blood stasis type).
【學位授予單位】：黑龍江中醫(yī)藥大學
【學位級別】：碩士
【學位授予年份】：2017
【分類號】：R276.1

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