本文選題：中醫(yī)　切入點：中藥內(nèi)服　出處：《山西中醫(yī)學院》2016年碩士論文

【摘要】：目的本研究以中藥內(nèi)服聯(lián)合穴位敷貼治療兒童哮喘緩解期肺脾氣虛證,通過觀察對相關臨床癥狀的改善情況,以及對患兒肺功能中用力肺活量(FVC)、一秒用力呼氣容積(FEV1)及呼氣峰流速(PEF)的三項指標的影響,來判定臨床療效,從而為中醫(yī)內(nèi)外合治干預哮喘提供客觀依據(jù)。方法將109例就診于上海市中醫(yī)醫(yī)院屬哮喘緩解期肺脾氣虛證的患兒,隨機分為治療組和對照組,其中治療組55例,對照組54例。對照組予中藥內(nèi)服治療,每天2次,療程1-3月,治療組在對照組治療方法基礎上加用黃芩咳喘散穴位敷貼聯(lián)合離子導入技術治療,從初伏開始,每周治療2次,6次為一個療程,共治療3個療程。兩組患兒在觀察期間若哮喘急性發(fā)作,依據(jù)GINA治療方案,用ICS(布地奈德混懸劑)+β2受體激動劑(可必特)治療,必要時加用抗過敏、抗感染治療。觀察患者治療后的中醫(yī)單項癥狀積分、中醫(yī)證候積分以及治療后3個月、6個月觀察肺功能相關指標,系統(tǒng)評價中藥內(nèi)服聯(lián)合穴位敷貼對兒童哮喘緩解期肺脾氣虛證患者的綜合臨床療效及對肺功能的影響。結(jié)果治療后兩組的總療效比較,治療組和對照組分別為96.36%和90.74%,兩組比較,差異具有統(tǒng)計學意義(P0.05),治療組療效優(yōu)于對照組。治療后,兩組癥狀及中醫(yī)證候積分都較治療前減少,且治療組優(yōu)于對照組,差異具有統(tǒng)計學意義(P0.05),說明治療組在改善中醫(yī)癥狀方面有明顯優(yōu)勢。治療后,兩組肺功能指標中FEV1、FVC、PEF三項指標在治療后3個月和6個月均較治療前有顯著提高(P0.05),組間對比,治療組優(yōu)于對照組(P0.05)。結(jié)論中藥內(nèi)服聯(lián)合穴位敷貼可以有效改善兒童哮喘緩解期肺脾氣虛證的主要相關臨床癥狀,且能夠明顯改善患兒肺功能。
[Abstract]:Objective to study the effect of traditional Chinese medicine combined with acupoint application on lung and spleen qi deficiency syndrome in children with asthma in remission period, and to observe the improvement of related clinical symptoms.The effects of three indexes on forced vital capacity (FV), forced expiratory volume (FEV _ 1) and peak expiratory flow rate (PEF) in children's lung function were also studied to evaluate the clinical efficacy and provide an objective basis for the intervention of asthma with internal and external treatment of traditional Chinese medicine.Methods 109 children with lung and spleen Qi deficiency syndrome in remission of asthma were randomly divided into treatment group (55 cases) and control group (54 cases).The control group was treated with traditional Chinese medicine orally, twice a day for 1-3 months. The treatment group was treated with Huangqin KechuanSan acupoint application combined with iontophoresis technique on the basis of the control group's treatment method. From the first volt, the treatment group was treated twice a week for 6 times as a course of treatment.There were 3 courses of treatment.During the observation period, the children in both groups were treated with GINA (budesonide suspension) 尾 _ 2 receptor agonist (Corbitt), as well as anti-allergic and anti-infective therapy according to the GINA regimen.Observe the single symptom score, TCM syndrome score and pulmonary function related indexes after 3 months and 6 months after treatment.Objective: to evaluate the comprehensive clinical effect of Chinese herbal medicine combined with acupoint application on children with asthmatic asthmatic patients with deficiency of lung temper and its effect on lung function.Results the total curative effect of the two groups after treatment was 96.36% and 90.74% respectively in the treatment group and the control group, the difference was statistically significant (P 0.05). The curative effect of the treatment group was better than that of the control group.After treatment, the symptoms and TCM syndrome scores of the two groups were decreased compared with before treatment, and the treatment group was better than the control group, the difference was statistically significant (P 0.05), which indicated that the treatment group had obvious advantages in improving TCM symptoms.After treatment, the three indexes of FEV1 FVCU PEF in the two groups were significantly higher than those before treatment 3 and 6 months after treatment, and the comparison between the two groups showed that the treatment group was better than the control group.Conclusion traditional Chinese medicine combined with acupoint application can effectively improve the main clinical symptoms of lung and spleen qi deficiency syndrome in children with asthma, and can obviously improve the lung function of children.
【學位授予單位】：山西中醫(yī)學院
【學位級別】：碩士
【學位授予年份】：2016
【分類號】：R272

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