本文選題：麝香通心滴丸　切入點(diǎn)：穩(wěn)定型心絞痛　出處：《黑龍江中醫(yī)藥大學(xué)》2017年碩士論文

【摘要】：目的:采用隨機(jī)、雙盲、安慰劑對(duì)照方法觀察麝香通心滴丸對(duì)冠心病穩(wěn)定型心絞痛(痰熱瘀阻型)患者中醫(yī)證候和平板運(yùn)動(dòng)試驗(yàn)結(jié)果的影響,以評(píng)價(jià)麝香通心滴丸的有效性,為臨床治療穩(wěn)定型心絞痛(痰熱瘀阻型)提供依據(jù)。方法:選擇2015年5月至2016年7月來(lái)自黑龍江中醫(yī)藥大學(xué)附屬第一醫(yī)院門診的患者,均自愿簽署患者知情同意書。經(jīng)過(guò)2周導(dǎo)入洗脫期,將符合納入標(biāo)準(zhǔn)的20例,按照1:1隨機(jī)分為2組,其中試驗(yàn)組與對(duì)照組分別10例。兩組患者均在西醫(yī)冠心病心絞痛標(biāo)準(zhǔn)化治療的基礎(chǔ)上,試驗(yàn)組以麝香通心滴丸口服,對(duì)照組以麝香通心滴丸安慰劑口服,一次2丸,一日3次,共56±7天。記錄試驗(yàn)前后患者基本生命體征、中醫(yī)證候積分表、標(biāo)準(zhǔn)BRUCE運(yùn)動(dòng)平板試驗(yàn)指標(biāo)。結(jié)果:1、在中醫(yī)證候總積分方面,試驗(yàn)組治療后明顯低于治療前,差異具有統(tǒng)計(jì)學(xué)意義(P0.05)。2、在中醫(yī)證候積分總有效率、單項(xiàng)癥狀有效率(除心悸、形體肥胖)方面,試驗(yàn)組在治療后均高于對(duì)照組,差異具有統(tǒng)計(jì)學(xué)意義(P0.05)。3、在ST段下降最大幅度和(mv)方面,試驗(yàn)組在治療后明顯低于治療前,差異有統(tǒng)計(jì)學(xué)意義(P0.05);治療后,試驗(yàn)組明顯低于對(duì)照組,差異有統(tǒng)計(jì)學(xué)意義(P0.05)。結(jié)論:1、麝香通心滴丸能改善穩(wěn)定型心絞痛(痰熱瘀阻型)患者的中醫(yī)證候。2、麝香通心滴丸能改善冠心病穩(wěn)定型心絞痛(痰熱瘀阻型)患者平板運(yùn)動(dòng)試驗(yàn)中的缺血程度。
[Abstract]:Objective: to observe the effect of Shexiang Tongxin dropping pills on TCM syndromes and treadmill exercise test results in patients with stable angina pectoris (phlegm and heat stasis type) of coronary heart disease (CHD) by randomized, double-blind and placebo control methods, and to evaluate the effectiveness of Shexiang Tongxin dropping pills. Methods: from May 2015 to July 2016, patients from the first affiliated Hospital of Heilongjiang University of traditional Chinese Medicine were selected from outpatient clinic of the first affiliated Hospital of Heilongjiang University of traditional Chinese Medicine to provide the basis for clinical treatment of stable angina pectoris (phlegm and heat stasis type). 20 patients who met the inclusion criteria were randomly divided into 2 groups according to 1:1. There were 10 cases in the trial group and 10 cases in the control group. On the basis of the standardized treatment of angina pectoris in western medicine, the experimental group was given Shexiang Tongxin dropping pills orally, and the control group was given Shexiang Tongxin dropping pills placebo, 2 pills once a day, 3 times a day. A total of 56 鹵7 days. Before and after the test, the patients' basic vital signs, TCM syndromes integral table and standard BRUCE exercise plate test indexes were recorded. Results: 1. In the total score of TCM syndromes, the experimental group was significantly lower after treatment than before treatment. The difference was statistically significant (P 0.05). The total effective rate of TCM syndromes integral and the effective rate of single symptom (except palpitation, body obesity) in the experimental group were higher than those in the control group after treatment. The difference was statistically significant (P0.05U. 3). In the aspect of the maximum decrease of St segment and MV), the experimental group was significantly lower than that before treatment, the difference was statistically significant (P0.05), after treatment, the trial group was significantly lower than the control group. The difference was statistically significant (P 0.05). Conclusion:% 1, Shexiang Tongxin dropping pill can improve TCM syndrome of stable angina pectoris (phlegm heat stasis type), and Shexiang Tongxin dropping pill can improve coronary heart disease stable angina pectoris (phlegm heat stasis type) patients. The degree of ischemia in the plate exercise test.
【學(xué)位授予單位】：黑龍江中醫(yī)藥大學(xué)
【學(xué)位級(jí)別】：碩士
【學(xué)位授予年份】：2017
【分類號(hào)】：R259

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