本文選題：四黃痔瘡膏　切入點(diǎn)：混合痔術(shù)后常見并發(fā)癥　出處：《云南中醫(yī)學(xué)院》2017年碩士論文

【摘要】：目的:觀察四黃痔瘡膏治療濕熱下注型混合痔術(shù)后常見并發(fā)癥的便時(shí)疼痛、肛緣水腫、便血、滲液、創(chuàng)面愈合率的臨床療效觀察及新生肉芽組織中羥脯胺酸含量,旨在縮短混合痔術(shù)后恢復(fù)時(shí)間,減輕患者痛苦,探索四黃痔瘡膏促進(jìn)創(chuàng)傷修復(fù)與羥脯胺酸的關(guān)系。方法:選擇符合納入標(biāo)準(zhǔn)的60例均行混合痔外剝內(nèi)扎術(shù)的患者按根據(jù)隨機(jī)數(shù)字表法分為治療組、對照組兩組,每組各例30例。兩組術(shù)后均采相同的基礎(chǔ)治療,治療組予以四黃痔瘡膏換藥;對照組予馬應(yīng)龍麝香痔瘡膏換藥,療程為11天。觀察術(shù)后治療前及治療后便時(shí)肛門疼痛、水腫、便時(shí)出血、滲液的癥狀積分下降值及便時(shí)肛門疼痛起效時(shí)間和消除時(shí)間,術(shù)后11天時(shí)創(chuàng)面愈合率;第6天時(shí)治療組、對照組按照隨機(jī)數(shù)字表法各取10例肉芽組織測定羥脯胺酸的含量。結(jié)果:(1)術(shù)后第6天治療組在緩解便時(shí)疼痛、改善水腫、減少便時(shí)出血及創(chuàng)面滲液方面均優(yōu)于對照組(P0.05)具有統(tǒng)計(jì)學(xué)意義,術(shù)后11天各癥狀無差異,無統(tǒng)計(jì)學(xué)意義。(2)術(shù)后便時(shí)疼痛起效、消除時(shí)間均優(yōu)于對照組(P0.05)。(3)術(shù)后11天治療組創(chuàng)面面積減少率均高于對照組(P0.05),差異明顯,有統(tǒng)計(jì)學(xué)意義,術(shù)后11天治療組四黃痔瘡膏觀察總體療效率分別為96.67%,對照組馬應(yīng)龍麝香痔瘡膏觀察總體有效率為86.67%,治療組與對照組比較存在顯著性差異(P0.05),治療組(四黃痔瘡膏)效果明顯好于對照組(馬應(yīng)龍麝香痔瘡膏),術(shù)后第6天肉芽組織中羥脯胺酸含量高于對療組(P0.05),差異有統(tǒng)計(jì)學(xué)意義,說明治療組創(chuàng)面愈合時(shí)間短、愈合快可能與羥脯胺酸含量增加有關(guān)。結(jié)論:四黃痔瘡膏具有清熱利濕,行氣消腫,活血止痛之功,外用治療濕熱下注型混合痔術(shù)后能明顯改善術(shù)后便時(shí)疼痛、肛緣水腫、便時(shí)出血、滲液等癥狀,減少便時(shí)疼痛時(shí)間,增加羥脯胺酸含量促進(jìn)創(chuàng)面肉芽生長,縮短創(chuàng)面愈合時(shí)間,縮短術(shù)后療程,減輕患者痛苦。
[Abstract]:Objective: To observe the four yellow hemorrhoids ointment damp type mixed hemorrhoid postoperative common complications of pain, hematochezia, anal edema, exudation, hydroxyproline content of the wound healing rate of clinical curative effect and granulation tissue, to shorten the recovery time of postoperative mixed hemorrhoids, relieve the pain of patients, explore four Huang hemorrhoids ointment to promote wound repair and hydroxyproline. Methods: 60 cases met inclusion criteria were mixed hemorrhoids patients according to randomly divided into treatment group and control group two groups, each group of 30 patients were collected. The same basic treatment in two groups after the treatment group received four yellow ointment dressing change; control group was treated with Musk Hemorrhoids Ointment, treatment for 11 days. Before and after treatment were observed after postoperative anal pain, then when will edema, bleeding, oozing and then decreased when the symptom onset time of anal pain And the elimination time, 11 days after surgery when the wound healing rate; sixth day treatment group and control group randomly from each of the 10 cases of granulation tissue, determination of hydroxyproline content. Results: (1) after sixth days of treatment group improved in relieving pain and edema, and reduce bleeding and wound exudate were better than the control group (P0.05) with statistical significance, 11 days after operation the symptoms had no difference, no statistical significance. (2) after the operation when the pain onset, the elimination time was better than the control group (P0.05). (3) after 11 days of treatment group were higher than that of the wound area reduction rate the control group (P0.05), significant difference was statistically significant, 11 days after treatment group four yellow ointment observation total therapeutic rate was 96.67%, the control group of Musk Hemorrhoids Ointment observe the total effective rate is 86.67%, compared with the control group, there was significant difference (P0.05), treatment group (four yellow hemorrhoids cream) effect Significantly better than the control group (mayingnong cream), hydroxyproline content after sixth days of granulation tissue was higher than that of treatment group (P0.05), the difference was statistically significant, indicating that the treatment group wound healing time is short, fast healing may be associated with increased hydroxyproline content. Conclusion: four yellow hemorrhoids ointment has heat and dampness, Qi blood swelling, alleviating pain, topical treatment of damp heat type mixed hemorrhoid surgery can significantly improve the postoperative and pain, anal edema, hemorrhage and exudation, and other symptoms, reduce pain, increase hydroxyproline content and promote wound granulation tissue growth, shorten the wound healing time, shorten the postoperative treatment, to alleviate the suffering of patients.

【學(xué)位授予單位】：云南中醫(yī)學(xué)院
【學(xué)位級別】：碩士
【學(xué)位授予年份】：2017
【分類號】：R266

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本文編號：1661921