本文選題：穴位貼敷　切入點：盆腔炎性疾病后遺癥　出處：《南京中醫(yī)藥大學(xué)》2017年碩士論文

【摘要】：目的:通過觀察中醫(yī)外治法穴位貼敷配合中藥口服的聯(lián)合治療方法,以及僅僅單純口服中藥療法,總結(jié)分析兩種方式治療氣滯血瘀型盆腔炎性疾病后遺癥的臨床療效差異,總結(jié)穴位貼敷在治療盆腔炎性疾病后遺癥時發(fā)揮的臨床意義,并探討其作用機(jī)制,尋找最佳治療方案,體現(xiàn)中醫(yī)藥特色外治療法的優(yōu)勢,以進(jìn)一步提高治愈率與遠(yuǎn)期療效、縮短療程、降低復(fù)發(fā)率、減少患者的痛苦,為臨床推廣應(yīng)用提供依據(jù)。方法:采用隨機(jī)、平行對照原則,納入符合標(biāo)準(zhǔn)患者44例,分為治療組及對照組。治療組予穴位貼敷配合中藥湯劑盆腔炎方口服,對照組則僅予中藥湯劑盆腔炎方口服治療。兩組患者治療周期均3個月,分別記錄治療前后的癥狀體征評分、盆腔血流動力學(xué)變化及炎癥因子白介素-8(IL-8)的變化,通過比較兩組治療前后檢查結(jié)果,評估兩種治療方式的效果差異。結(jié)果:(1)兩組患者治療前后綜合療效、綜合、癥狀、體征積分經(jīng)統(tǒng)計學(xué)分析均具有顯著性差異(P0.05)(2)①治療組患者治療后子宮左右側(cè)動脈搏動指數(shù)、阻力指數(shù)及子宮右側(cè)動脈最大流速,經(jīng)統(tǒng)計具有統(tǒng)計學(xué)意義(P0.05)②治療組治療后子宮左側(cè)動脈的最大流速無明顯差異(P0.05)。③對照組治療后子宮左右側(cè)動脈搏動指數(shù)、阻力指數(shù)、最大流速差異無統(tǒng)計學(xué)意義(P0.05)。(3)①治療組與對照組治療前后血清中IL-8值相比,均有統(tǒng)計學(xué)差異(P0.05)。②治療組與對照組治療后血清中IL-8值相比,有統(tǒng)計學(xué)差異(P0.05)。結(jié)論:中藥湯劑口服及穴位貼敷療法均能改善盆腔炎性疾病后遺癥患者的癥狀及體征,但兩者配合治療的效果明顯優(yōu)于單純中藥口服治療,聯(lián)合療法也能更好的改善盆腔血流動力學(xué),改善IL-8在血清中的表達(dá),證明穴位貼敷作為中醫(yī)特色外治法,配合中藥湯劑口服的聯(lián)合療法治療氣滯血瘀型盆腔炎性疾病后遺癥效果明顯優(yōu)于單純中藥療法,應(yīng)當(dāng)為臨床廣泛運用。
[Abstract]:Objective: to observe the combined therapy of acupoint application and oral administration of traditional Chinese medicine, and to summarize and analyze the difference of clinical curative effect between the two methods in treating the sequelae of pelvic inflammatory disease of qi stagnation and blood stasis type. To summarize the clinical significance of acupoint application in the treatment of the sequelae of pelvic inflammatory disease, to explore its mechanism, to find the best treatment scheme and to reflect the advantages of external treatment with Chinese medicine, so as to further improve the cure rate and long-term curative effect. To shorten the course of treatment, reduce the recurrence rate, reduce the pain of the patients, and provide the basis for clinical application. The treatment group was divided into treatment group and control group. The treatment group was treated with acupoint application combined with traditional Chinese medicine decoction pelvic inflammatory prescription, while the control group was only treated with traditional Chinese medicine decoction pelvic inflammatory prescription. The treatment period of both groups was 3 months. The scores of symptoms and signs, the changes of pelvic hemodynamics and the changes of interleukin-8 (IL-8) were recorded before and after treatment, and the results before and after treatment were compared between the two groups. Results there were significant differences in the scores of comprehensive curative effect, syntheses, symptoms and signs before and after treatment between the two groups. The pulsatility index of left and right uterine artery was significantly different in the treatment group (P 0.05). The resistance index and the maximum velocity of right uterine artery were statistically significant. There was no significant difference in the maximal velocity of left uterine artery after treatment in P0.05T-2 treatment group. The pulsatility index and resistance index of left and right uterine artery in control group were not significantly different after treatment. There was no significant difference in the maximum flow velocity between the two groups before and after treatment. There were significant differences in serum IL-8 levels between the two groups before and after treatment. There was also significant difference between the treatment group and the control group in the serum IL-8 levels after treatment. Conclusion: both oral Chinese medicine decoction and acupoint application therapy can improve the symptoms and signs of patients with pelvic inflammatory disease sequelae, but the effect of combined treatment is obviously better than that of traditional Chinese medicine alone. The combination therapy can also improve the pelvic hemodynamics, improve the expression of IL-8 in serum, prove that acupoint application is the characteristic external therapy of traditional Chinese medicine. The combined therapy combined with traditional Chinese medicine decoction in treating the sequelae of Qi stagnation and Blood stasis type pelvic inflammatory disease is obviously better than that of traditional Chinese medicine alone, and should be widely used in clinical practice.
【學(xué)位授予單位】：南京中醫(yī)藥大學(xué)
【學(xué)位級別】：碩士
【學(xué)位授予年份】：2017
【分類號】：R271.9

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