本文選題：圍絕經(jīng)期　切入點：尿道綜合征　出處：《黑龍江中醫(yī)藥大學(xué)》2017年碩士論文　論文類型：學(xué)位論文

【摘要】：目的:通過滋陰通淋湯配合針刺治療圍絕經(jīng)期尿道綜合征的臨床觀察,評價針藥結(jié)合治療圍絕經(jīng)期尿道綜合征的確切療效和安全性,探求圍絕經(jīng)期尿道綜合征更為科學(xué)的治療方案。方法:選取符合圍絕經(jīng)期尿道綜合征納入標準患者95例,按隨機數(shù)字表法隨機分為中藥組32例,針刺組32例和針藥結(jié)合組31例。中藥組給予導(dǎo)師臨床經(jīng)驗方滋陰通淋湯口服治療;針刺組針刺中極穴、委中穴、肝俞穴、腎俞穴治療;針藥結(jié)合組采用針刺結(jié)合中藥自擬方口服治療;治療時間均為3個月。觀察治療前后中醫(yī)證候積分、國際下尿路癥狀評分、血清雌二醇、卵泡刺激素、黃體生成素,并對此進行分析,觀察三組療效。結(jié)果:1、國際下尿路癥狀評分療效比較:中藥組總有效率83.87%,針刺組總有效率76.67%,針藥結(jié)合組總有效率93.55%。三組療效比較,中藥組和針刺組療效無明顯差異(P0.017),而針藥結(jié)合組療效明顯優(yōu)于中藥組和針刺組(P0.017)。2、中醫(yī)癥狀積分療效比較:中藥組總有效率77.42%,針刺組總有效率73.33%,針藥結(jié)合組總有效率90.32%。三組療效比較,中藥組和針刺組療效無明顯差異(P0.017),針藥結(jié)合組療效明顯優(yōu)于中藥組和針刺組(P0.017)。3、國際下尿路癥狀評分比較:三組治療后國際下尿路癥狀評分較治療前均下降,差異有顯著統(tǒng)計學(xué)意義(P0.01);治療后國際下尿路癥狀評分組間比較,中藥組和針刺組在改善國際下尿路癥狀方面無明顯差異(P0.05),針藥結(jié)合組在改善國際下尿路癥狀方面優(yōu)于中藥組及針刺組(P0.05)。4、中醫(yī)癥狀積分比較:三組治療后中醫(yī)癥狀積分較治療前均下降,差異有顯著統(tǒng)計學(xué)意義(P0.01);治療后中醫(yī)癥狀積分組間比較,中藥組和針刺組在改善中醫(yī)癥狀方面無明顯差異(P0.05),針藥結(jié)合組在改善中醫(yī)癥狀方面優(yōu)于中藥組及針刺組(P0.05)。5、激素水平改善情況比較:卵泡刺激素水平比較:三組治療后卵泡刺激素水平較療前均下降,中藥組、針刺組治療前后比較無明顯差異(P0.05),針藥結(jié)合組治療前后比較差異有統(tǒng)計學(xué)意義(P0.05);治療后組間比較,中藥組與針刺組無明顯差異(P0.05),針藥結(jié)合組優(yōu)于中藥組、針刺組(P0.05)。血清雌二醇水平比較:三組治療后血清雌二醇水平較療前均上升,中藥組、針刺組治療前后比較無明顯差異(P0.05),針藥結(jié)合組治療前后比較差異有統(tǒng)計學(xué)意義(P0.05);治療后組間比較,中藥組與針刺組無明顯差異(P0.05),針藥結(jié)合組優(yōu)于中藥組、針刺組(P0.05)。黃體生成素水平比較:三組治療前后比較均無明顯差異(P0.05);治療后組間比較,三組間無明顯差異(P0.05)。結(jié)論:中藥組、針刺組、針藥結(jié)合組治療圍絕經(jīng)期尿道綜合征皆有療效。其中針藥結(jié)合組治療圍絕經(jīng)期尿道綜合征療效顯著,且明顯優(yōu)于中藥組及針刺組,臨床療效確切,安全性好,是治療圍絕經(jīng)期尿道綜合征的較好方法之一。
[Abstract]:Objective: through Ziyin Tonglin Decoction Combined with clinical observation of menopausal urethral syndrome treated with acupuncture, acupuncture combined with evaluation of the treatment of perimenopausal urethral the exact efficacy and safety of perimenopausal syndrome, explore the urethral syndrome more scientific treatment. Methods: with menopause urethral syndrome encircled the inclusion criteria of 95 cases of patients. Randomly divided into treatment group of 32 cases, 32 cases in the acupuncture group and acupuncture group of 31 cases. The TCM group was given mentor clinical experience Ziyin Tonglin Decoction oral treatment; Acupuncture Acupuncture in acupoints Weizhong, Ganshu acupuncture point, Shenshu acupoint therapy; acupuncture combined with medicine group were treated with acupuncture combination of Chinese herbal medicine decoction oral treatment; the treatment time was 3 months. Before and after treatment of TCM syndrome integral, the lower urinary tract symptom score, serum estradiol, follicle stimulating hormone, luteinizing hormone, and conduct analysis, observation of three groups Effect. Results: 1, international comparison of lower urinary tract symptom score: the treatment group curative effect the total efficiency of 83.87%, total effective rate in the acupuncture group 76.67%, acupuncture medicine group total efficiency 93.55%. comparison of the three groups had no significant difference, the Chinese medicine group and acupuncture group (P0.017), and the curative effect of combined acupuncture and medicine group curative effect is obviously superior to traditional Chinese medicine group and acupuncture group (P0.017.2), TCM symptom efficacy: Chinese medicine group total effective rate was 77.42%, total effective rate in the acupuncture group 73.33%, acupuncture medicine group total efficiency 90.32%. comparison of the three groups had no significant difference, the Chinese medicine group and acupuncture group (P0.017), the curative effect of combined acupuncture and medicine group was better than the traditional Chinese medicine group and the acupuncture group (P0.017.3), the international comparison of lower urinary tract symptoms score: three groups after treatment the lower urinary tract symptoms score before treatment were decreased, the difference was statistically significant (P0.01); after treatment the lower urinary tract symptoms score between the two groups, Chinese medicine group and acupuncture group in change No significant difference between the good international lower urinary tract symptoms (P0.05), to improve the international lower urinary tract symptoms is better than that of the traditional Chinese medicine group and acupuncture group, acupuncture combined with medicine group (P0.05.4), comparison of TCM symptom score: three groups after treatment of TCM symptom score before treatment were decreased, there was significant difference in statistical significance (P0.01); after the treatment of TCM symptom scores between the two groups, Chinese medicine group and acupuncture group in improving TCM symptoms had no significant difference (P0.05), acupuncture combined with medicine group in improving TCM symptoms than the traditional Chinese medicine group and acupuncture group (P0.05.5), compare the hormone level to improve the situation: FSH level comparison: three groups after treatment FSH levels were decreased compared with before treatment, traditional Chinese medicine group, acupuncture group before and after treatment had no significant difference (P0.05), acupuncture medicine group before and after treatment, the difference was statistically significant (P0.05); the treatment group compared with traditional Chinese medicine group and the acupuncture group had no significant difference (P0 .05), acupuncture medicine group is better than the traditional Chinese medicine group, acupuncture group (P0.05). The serum estradiol level: serum estradiol levels were increased compared with before treatment, after treatment of the three groups of Chinese medicine group, acupuncture group before and after treatment had no significant difference (P0.05), acupuncture medicine group before and after treatment, the difference was statistically significant (P0.05); comparison between groups after treatment, Chinese medicine group and the acupuncture group had no significant difference (P0.05), acupuncture medicine group is better than the traditional Chinese medicine group, acupuncture group (P0.05). Comparison of luteinizing hormone levels: the three groups before and after treatment showed no significant difference (P0.05); comparison between groups after treatment, no significant difference between the three groups (P0.05). Conclusion: the traditional Chinese medicine group, acupuncture group, peri menopausal urethral syndrome has the curative effect of combined acupuncture and medicine treatment. Acupuncture combined with medicine group treatment of perimenopausal urethral syndrome is effective, and is superior to the traditional Chinese medicine group and acupuncture group, clinical curative effect, good safety, is the treatment of perimenopause One of the better methods of urethral syndrome.

【學(xué)位授予單位】：黑龍江中醫(yī)藥大學(xué)
【學(xué)位級別】：碩士
【學(xué)位授予年份】：2017
【分類號】：R271.9

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