本文選題：圍絕經(jīng)期綜合征　切入點(diǎn)：常規(guī)針刺　出處：《湖北中醫(yī)藥大學(xué)》2017年碩士論文　論文類型：學(xué)位論文

【摘要】：目的:圍絕經(jīng)期綜合征(perimenopausal syndrome,PMS)是女性從中年到老年過渡時(shí)期的常見病、多發(fā)病,嚴(yán)重影響女性的生理和心理健康,國內(nèi)外研究表明常規(guī)針刺或電針治療PMS療效好、不良反應(yīng)少,本研究旨在進(jìn)一步觀察二者治療PMS的臨床療效差異及安全性,為臨床上針刺方案的選擇提供依據(jù)。方法:將符合標(biāo)準(zhǔn)的50例PMS患者隨機(jī)分為兩組,分別為常規(guī)針刺組(25例)和電針組(25例)。常規(guī)針刺組采用常規(guī)行針手法加假電針的治療方式,治療穴位選取天樞、關(guān)元、子宮、三陰交;電針組取穴同常規(guī)針刺組,采用電針加假行針(針刺過程中不行手法操作)的方式,疏密波,頻率10Hz/50Hz,強(qiáng)度0.5-1.0m A。治療時(shí)留針30 min,每周3次,共治療8周。觀察入組時(shí)、治療第4周、治療第8周后焦慮自評(píng)量表(SAS)、絕經(jīng)癥狀評(píng)價(jià)量表(MRS)、圍絕經(jīng)期生存質(zhì)量量表(MENQOL)、抑郁自評(píng)量表(SDS)評(píng)分以及治療前后血清卵泡刺激素(FSH)、黃體生成素(LH)、雌激素(E2)的變化及不良反應(yīng)發(fā)生情況。結(jié)果:1.與本組治療前的各項(xiàng)評(píng)分相比較,常規(guī)針刺組治療第4周、第8周時(shí)MRS、MENQOL、SAS、SDS評(píng)分均有下降(P0.05);與治療第4周比,治療8周時(shí)各評(píng)分仍有下降(P0.05)。電針組也得到相似的結(jié)果,組間比較無統(tǒng)計(jì)學(xué)差異(P0.05)。2.常規(guī)針刺組完成病例23例,治愈1例,顯效3例,有效9例,總有效率為56.52%;電針組完成病例23例,治愈1例,顯效1例,有效12例,總有效率為60.87%。兩組比較差異無統(tǒng)計(jì)學(xué)意義(P0.05)。3.與本組治療前比較,常規(guī)針刺組在治療后FSH、LH值有所下降,但差異無統(tǒng)計(jì)學(xué)意義(P0.05);治療后E2值有上升趨勢(shì),但差異無統(tǒng)計(jì)學(xué)意義(P0.05)。電針組也得到相似的結(jié)果。組間比較無統(tǒng)計(jì)學(xué)差異(P0.05)。4.兩組PMS患者在試驗(yàn)中未出現(xiàn)嚴(yán)重不良反應(yīng)。結(jié)論:1.常規(guī)針刺治療與電針治療對(duì)于PMS患者均有較為肯定的臨床療效,且安全、不良反應(yīng)少。2.常規(guī)針刺治療與電針治療可以改善絕經(jīng)相關(guān)癥狀,改善絕經(jīng)期抑郁、焦慮癥狀,提高患者的生活和生存質(zhì)量,并且隨著治療周期的延長,絕經(jīng)癥狀得到進(jìn)一步改善。二者療效相當(dāng),無明顯差異。3.常規(guī)針刺治療與電針治療未能明顯改變患者的激素水平。以上結(jié)論有待臨床試驗(yàn)進(jìn)一步驗(yàn)證。
[Abstract]:Objective: peri-menopausal syndrome perimenopausal syndrome (PMSs) is a common disease in women during the transition from middle age to old age. The purpose of this study was to observe the clinical efficacy and safety of the two groups in the treatment of PMS, and to provide the basis for the choice of acupuncture regimen. Methods: 50 patients with PMS who met the criteria were randomly divided into two groups. Routine acupuncture group (n = 25) and electroacupuncture group (n = 25). The conventional acupuncture group was treated by conventional acupuncture manipulation plus false electroacupuncture, and the acupoints were selected as Tianshu, Guanyuan, uterus and Sanyinjiao, and the acupoints in the electroacupuncture group were compared with those in the conventional acupuncture group. Electroacupuncture plus false acupuncture (no manual operation in the process of acupuncture) was used, the frequency was 10 Hz / 50 Hz, the intensity was 0.5-1.0 Ma. The acupuncture was kept for 30 minutes, 3 times a week for 8 weeks. The changes of serum follicle stimulating hormone (FSH), luteinizing hormone (LH), luteinizing hormone (LHN), estrogen (E _ 2) were assessed by self-rating anxiety scale (SAS), postmenopausal symptom evaluation scale (MRS), postmenopausal quality of life scale (MENQOLN), self-rating depression scale (SDS) after 8 weeks of treatment. Results: 1.Compared with the scores before treatment, In the routine acupuncture group, at the 4th week and the 8th week, the scores of MRSU MENQOLN SASX SDS were all decreased (P 0.05), compared with the 4th week of treatment, the scores of each score were still decreased at the 8th week. The results of electroacupuncture group were similar. There was no statistical difference between the two groups (P 0.05). 23 cases were cured, 1 case was cured, 3 cases were effective, 9 cases were effective, and the total effective rate was 56.52% in the routine acupuncture group, while in the electroacupuncture group, 1 case was cured, 1 case was cured, 1 case was effective, 12 cases were effective. The total effective rate was 60.87.The difference between the two groups was not statistically significant (P0.050.3.Compared with that before treatment, the FSH LH value in the routine acupuncture group decreased, but the difference was not statistically significant (P 0.05), the E 2 value increased after treatment. But the difference was not statistically significant (P 0.05). Similar results were obtained in the electroacupuncture group. There was no significant difference between the two groups. There were no serious adverse reactions in the two groups of PMS patients. Conclusion 1. Routine acupuncture and electroacupuncture treatment have no significant adverse effects on PMS. All of them had positive clinical effects. Routine acupuncture and electroacupuncture can improve menopausal symptoms, improve postmenopausal depression and anxiety symptoms, and improve patients' life and quality of life. The symptoms of menopause were further improved, the curative effect was similar, there was no significant difference between them. 3. Routine acupuncture treatment and electroacupuncture treatment could not obviously change the hormone level of the patients. The above conclusions need to be further verified by clinical trials.
【學(xué)位授予單位】：湖北中醫(yī)藥大學(xué)
【學(xué)位級(jí)別】：碩士
【學(xué)位授予年份】：2017
【分類號(hào)】：R246.3

【參考文獻(xiàn)】

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本文編號(hào)：1629408