發(fā)布時間：2018-03-17 17:23

  本文選題：PCOS　切入點(diǎn)：易感體質(zhì)　出處：《河南中醫(yī)藥大學(xué)》2016年碩士論文　論文類型：學(xué)位論文

【摘要】：目的:本研究旨在通過體質(zhì)調(diào)查量表對鄭州地區(qū)多囊卵巢綜合征(Polycystic Ovarian Syndrome,PCOS)患者進(jìn)行體質(zhì)統(tǒng)計,了解PCOS患者體質(zhì)類型構(gòu)成狀況,計算出PCOS患者的易感體質(zhì),并分析出易感體質(zhì)與促黃體生成素(Luteinizing hormone,LH)、睪酮(Testostrn,T)、胰島素抵抗(Insulin Resistance,IR)的相關(guān)性,從而盡早對易感體質(zhì)進(jìn)行藥物、飲食、運(yùn)動等調(diào)體治療,針對性預(yù)防對于癥狀典型但激素水平測定正常的患者進(jìn)一步出現(xiàn)IR、高雄激素血(Hyperandrogenism,HA)、高LH等生化病理表現(xiàn),為PCOS的早期預(yù)防提供新思路和依據(jù)。方法:選取2015年4月~2016年2月就診于河南中醫(yī)藥大學(xué)第一附屬醫(yī)院婦科門診的113例確診為PCOS的鄭州地區(qū)患者,作為本研究的調(diào)查對象。先由受過培訓(xùn)的專業(yè)人員對表格進(jìn)行講解,再由患者在安靜環(huán)境下獨(dú)立填寫表格,最后由工作人員將所收集的調(diào)查結(jié)果進(jìn)行轉(zhuǎn)化分計算并錄入Excel,建立SPSS數(shù)據(jù)庫。計數(shù)資料采用獨(dú)立四表格Pearson(T≥5,n≥40)?2檢驗進(jìn)行分析,計量資料首先采用單樣本k-s檢驗法對其進(jìn)行正態(tài)性和方差齊性檢驗,如為正態(tài)分布且方差齊,則進(jìn)行兩個獨(dú)立樣本的t檢驗法進(jìn)行分析,若不符合正態(tài)分布,則進(jìn)行兩獨(dú)立樣本的非參數(shù)檢驗法進(jìn)行分析。結(jié)果:(1)鄭州地區(qū)113例PCOS患者體質(zhì)分布情況:陽虛質(zhì)52例(46.02%)、血瘀質(zhì)22例(19.47%)、痰濕質(zhì)13例(11.5%)、氣郁質(zhì)11例(9.73%)、濕熱質(zhì)5例(4.42%)、陰虛質(zhì)3例(2.65%)、氣虛質(zhì)3例(2.65%)平和質(zhì)2例(1.77%)、特稟質(zhì)2例(1.77%);其中非陽虛質(zhì)共61例(53.98%);(2)陽虛質(zhì)組患者的平均年齡為26.1±3.3歲,非陽虛質(zhì)組平均年齡為26.3±3.7歲,兩組比較(P0.05)無顯著性差異,無統(tǒng)計學(xué)意義;(3)兩組患者初潮年齡比較,陽虛質(zhì)組平均初潮年齡比非陽虛質(zhì)組患者的平均初潮年齡晚1年,有統(tǒng)計學(xué)意義(P0.05);(4)兩組患者LH異常升高(LH/FSH2)的發(fā)生率,陽虛質(zhì)組明顯高于非陽虛質(zhì)組,有統(tǒng)計學(xué)意義(P0.05);(5)陽虛質(zhì)組與非陽虛質(zhì)組HA發(fā)生率比較,陽虛質(zhì)組HA的發(fā)生率高于非陽虛質(zhì)組,差異有統(tǒng)計學(xué)意義(P0.05);(6)兩組患者肥胖發(fā)生情況:陽虛體質(zhì)組肥胖者28(53.84%)人,非陽虛體質(zhì)組肥胖者13(21.31%)人,兩組比較,差異有統(tǒng)計學(xué)意義(P0.05)。結(jié)論:(1)陽虛體質(zhì)是PCOS的易感體質(zhì);(2)陽虛體質(zhì)患者平均初潮年齡比非陽虛體質(zhì)患者的平均初潮年齡推遲將近1年。提示青春期的體質(zhì)狀態(tài)會影響患者月經(jīng)初潮年齡,陽虛體質(zhì)女性的初潮年齡一般會推遲,因此應(yīng)早于青春期就要重視對體質(zhì)的調(diào)理,預(yù)防PCOS的發(fā)生;(3)陽虛體質(zhì)的PCOS患者發(fā)生LH異常升高、IR、HA及肥胖的幾率均較非陽虛體質(zhì)患者大,應(yīng)重視對PCOS陽虛體質(zhì)進(jìn)行調(diào)體治療,預(yù)防相關(guān)疾病的發(fā)生。
[Abstract]:Objective: the purpose of this study was to investigate the constitution of polycystic Ovarian syndromes (PCOSs) patients with polycystic ovary syndrome (PCOS) in Zhengzhou area, and to find out the constitution of PCOS patients' physique types, and to calculate the susceptible constitution of PCOS patients. We also analyzed the correlation between susceptible constitution and luteinizing hormone (LHH), testosterone (Testostrn), insulin resistance (IRR), so as to treat susceptible constitution with medicine, diet, exercise and so on as soon as possible. For the patients with typical symptoms but normal hormone levels, there were further biochemical pathological manifestations such as IRI, hyperandrogenismHAI, high LH and so on. Methods: from April 2015 to February 2016, 113 patients diagnosed as PCOS in the gynecological outpatient department of the first affiliated Hospital of Henan University of traditional Chinese Medicine were selected. As the subject of this study, the form was explained by trained professionals, and then the patient filled out the form independently in a quiet environment. Finally, the investigation results collected by the staff were transformed into Excel, and the SPSS database was established. The counting data were counted by independent four tables, Pearson(T 鈮，

本文編號：1625721