失眠伴腸道功能異常的臨床初步觀察
發(fā)布時間:2018-03-14 00:48
本文選題:失眠 切入點:腸道功能異常 出處:《中國中醫(yī)基礎(chǔ)醫(yī)學(xué)雜志》2017年08期 論文類型:期刊論文
【摘要】:目的:通過分析失眠伴腸道功能異;颊叩呐R床特點及證候分布特征,研究失眠與腸道功能異常的關(guān)系。方法:采用橫斷面調(diào)查方法對238例失眠患者進行包括臨床癥狀、PSQI評分、HAMA評分等系統(tǒng)分析,對腸道功能正常與腸道功能異常2組進行比較分析,其中腸道功能異常主要以排便異常為主。結(jié)果:238例失眠患者中,伴有排便異;颊哒50.4%,排便異常主要分大便干、大便黏滯不爽、大便泄瀉幾種類型,失眠患者以中青年女性為多,主要從事腦力勞動,大多數(shù)性格急躁易怒、思慮過多。失眠伴有排便異;颊叩慕箲]程度偏高,臨床以心煩、腰膝酸軟、畏寒、口燥咽干、五心煩熱、脫發(fā)、發(fā)變白、脘悶食少、腹脹、口黏不爽、納食不消、咽中異物感、疲乏無力、邊有齒痕、舌苔厚等癥狀為特征性臨床表征。通過對失眠伴有腸道功能異;颊叩拿舾行院吞禺愋耘R床表征進行聚類分析,發(fā)現(xiàn)失眠伴腸道功能異;颊咭愿斡羝⑻、郁而化火、濕濁困阻為核心證候病機。結(jié)論:失眠患者中焦慮程度偏高的容易出現(xiàn)腸道功能異常,失眠伴腸道功能異;颊咭愿斡羝⑻、郁而化火、濕濁困阻為核心證候病機。且失眠與腸道功能異常存在一定相關(guān)性,根據(jù)腦腸軸的存在推測腦與腸存在一定的關(guān)聯(lián),有待進一步臨床研究證實。
[Abstract]:Objective: to analyze the clinical characteristics and syndromes distribution of insomnia patients with abnormal intestinal function. To study the relationship between insomnia and intestinal dysfunction. Methods: 238 patients with insomnia were analyzed systematically including clinical symptoms and PSQI score and Hama score. The normal intestinal function and abnormal intestinal function were compared between the two groups. Results of 238 patients with insomnia, 50.4 were accompanied by abnormal defecation. The abnormal defecation was mainly divided into dry stool, sticky defecation, diarrhea and several types of defecation. Most insomnia patients are young and middle-aged women, mainly engaged in mental work. Most of them are impatient and irritable, thinking too much. Patients with insomnia accompanied by abnormal defecation have a high degree of anxiety, clinical symptoms are upset, the waist and knee are sore, cold, and the mouth is dry. Five upset heat, hair loss, white hair, stomach-stuffy food less, abdominal distension, mouth sticky, food, pharynx foreign body feeling, fatigue, edge teeth marks, By cluster analysis of the sensitivity and specificity of the patients with insomnia accompanied with intestinal dysfunction, it was found that the patients with insomnia accompanied with abnormal intestinal function were characterized by liver depression and spleen deficiency. Conclusion: the patients with insomnia with high degree of anxiety are prone to abnormal intestinal function, and the patients with insomnia associated with abnormal intestinal function are characterized by liver depression and spleen deficiency, and the depression of fire. Dampness and turbid obstruction are the core syndromes, and insomnia has certain correlation with intestinal dysfunction. According to the existence of brain intestinal axis, it is inferred that there is a certain connection between brain and intestine, which needs further clinical research to prove.
【作者單位】: 北京中醫(yī)藥大學(xué);北京中醫(yī)藥大學(xué)東直門醫(yī)院;太原市中醫(yī)醫(yī)院;
【分類號】:R256.23
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