本文選題：中醫(yī)傳承輔助系統(tǒng)　切入點(diǎn)：月經(jīng)后期　出處：《山東中醫(yī)藥大學(xué)》2016年碩士論文　論文類型：學(xué)位論文

【摘要】：目的:本研究通過(guò)對(duì)古代中醫(yī)文獻(xiàn)中與月經(jīng)后期相關(guān)的中藥、方劑,進(jìn)行整理、總結(jié)、歸類,探尋月經(jīng)后期的基本理論及臨床用藥規(guī)律,包括組方規(guī)律,藥物、藥對(duì)及用藥指征,并進(jìn)行統(tǒng)計(jì)學(xué)分析,以期對(duì)月經(jīng)后期及其引起的不孕癥的治療提供更好的思路和方法。方法:系統(tǒng)回顧古代中醫(yī)文獻(xiàn),梳理出與月經(jīng)后期有關(guān)的中藥、方劑,篩選出有效方劑藥物,建立月經(jīng)后期方劑數(shù)據(jù)庫(kù),初步分析古代醫(yī)家治療月經(jīng)后期及其相關(guān)癥狀的臨床經(jīng)驗(yàn)和常用方藥。運(yùn)用“中醫(yī)傳承輔助系統(tǒng)”,應(yīng)用該軟件的集成規(guī)則分析,改進(jìn)互信息法、復(fù)雜系統(tǒng)熵聚類及無(wú)監(jiān)督的熵層次聚類等數(shù)據(jù)挖掘方法[1],從整體上對(duì)月經(jīng)后期的藥物使用規(guī)律及配伍規(guī)律進(jìn)行相關(guān)性分析。結(jié)果:通過(guò)中醫(yī)傳承輔助系統(tǒng)對(duì)治療月經(jīng)后期及其相關(guān)疾病的方劑進(jìn)行藥物頻次、關(guān)聯(lián)規(guī)則和復(fù)雜系統(tǒng)熵聚類的分析,綜合結(jié)果可以得出其組方規(guī)律、常用藥物、藥對(duì)及用藥指征。通過(guò)對(duì)古代文獻(xiàn)中298首處方的分析,用藥范圍結(jié)果表明,共涉及215味中藥,補(bǔ)虛藥、活血化瘀藥、理氣藥、溫里藥、利水滲濕藥、化痰止咳平喘藥、清熱藥等七類藥物是月經(jīng)后期最常用的藥類。藥物的四氣分析結(jié)果顯示:溫性藥物使用頻率最高;藥物五味分析結(jié)果顯示甘味、辛味、苦味藥物最常見(jiàn);藥物歸經(jīng)出現(xiàn)的頻率由高到低的次序是:肝經(jīng)、脾經(jīng)、心經(jīng)、腎經(jīng)、肺經(jīng)。利用“組方規(guī)律分析”版塊,系統(tǒng)性分析常用藥物及藥對(duì),并利用改進(jìn)的互信息法進(jìn)行藥物關(guān)聯(lián)性分析,形成34組常用藥對(duì),核心組合24個(gè),基于無(wú)監(jiān)督熵層次聚類法得出新方12個(gè),并對(duì)新方中的核心藥物進(jìn)行分析,為臨床臨證處理及藥物治療提供理論依據(jù)。結(jié)論:本研究通過(guò)建立月經(jīng)后期方藥數(shù)據(jù)庫(kù),利用中醫(yī)傳承輔助系統(tǒng)對(duì)方劑進(jìn)行錄入、整理,從多方面、多角度進(jìn)行分析,構(gòu)建規(guī)范的證候、方藥體系,對(duì)臨床工作有重要指導(dǎo)意義,值得進(jìn)一步推廣應(yīng)用。
[Abstract]:Objective: through sorting, summarizing and classifying the traditional Chinese medicine and prescriptions related to the late menstrual period in ancient Chinese medicine literature, to explore the basic theory and clinical drug use law of the late menstrual period, including the law of prescription and medicine. In order to provide a better idea and method for the treatment of postmenstrual period and infertility caused by it, a systematic review of the ancient Chinese medicine literature was carried out to sort out the Chinese medicine and prescription related to the late menstrual period. Screening out effective prescription drugs, establishing a database of prescriptions for late menstruation, A preliminary analysis of the clinical experience and common prescriptions of ancient physicians in the treatment of late menstruation and its related symptoms. By using the "Chinese Medicine inheritance Assistance system" and the application of the integrated rule analysis of the software, the mutual information method was improved. The methods of data mining such as entropy clustering and unsupervised entropy hierarchical clustering in complex systems [1] were used to analyze the correlation of drug use and compatibility in the later period of menstruation as a whole. Results: the treatment was treated by traditional Chinese Medicine (TCM) inheriting auxiliary system. The prescriptions for late menstruation and related diseases were used frequently. The association rules and entropy cluster analysis of complex systems can be used to find out the rule of its composition, common drugs, drug pairs and indications of drug use. By analyzing 298 prescriptions in ancient literature, the range of drug use shows that 215 kinds of traditional Chinese medicines are involved. Seven kinds of drugs, such as tonifying deficiency medicine, promoting blood circulation and removing blood stasis, regulating qi, warming medicine, promoting water and infiltrating dampness, resolving phlegm and relieving cough and relieving asthma, and clearing away heat, are the most commonly used drugs in the later period of menstruation. The results of four-gas analysis of the drugs show that: the use frequency of warm drugs is the highest; The results of the five-flavor medicine analysis showed that sweet taste, Xin flavor and bitter medicine were the most common drugs, and the frequency of the drug meridian appeared from high to low: liver, spleen, heart, kidney and lung. The common drugs and their pairs were systematically analyzed, and the improved mutual information method was used to analyze the drug association. 34 groups of common drug pairs were formed, with 24 core combinations, and 12 new drugs were obtained based on unsupervised entropy hierarchical clustering method. And the core drugs in the new prescription are analyzed to provide the theoretical basis for clinical clinical treatment and drug treatment. Conclusion: this study through the establishment of menstrual late prescription database, the use of traditional Chinese medicine inheritance assistance system for prescription input, collation, It is of great significance for clinical work to analyze from many aspects and angles, and to construct the standard syndrome and prescription system, which is worthy of further popularizing and applying.
【學(xué)位授予單位】：山東中醫(yī)藥大學(xué)
【學(xué)位級(jí)別】：碩士
【學(xué)位授予年份】：2016
【分類號(hào)】：R271.111

【參考文獻(xiàn)】

相關(guān)期刊論文 前10條

1 劉家貴;;針灸配合推拿治療月經(jīng)后期舉隅[J];黑龍江中醫(yī)藥;2013年04期

2 徐春娟;何曉暉;陳榮;;中醫(yī)婦科學(xué)奠基者陳自明學(xué)術(shù)思想的現(xiàn)代研究[J];江西中醫(yī)學(xué)院學(xué)報(bào);2012年06期

3 肖晶晶;朱穎;;中醫(yī)藥治療月經(jīng)后期的研究進(jìn)展[J];陜西中醫(yī)學(xué)院學(xué)報(bào);2012年03期

4 盧笑暉;單崎瑋;;基于中醫(yī)傳承輔助系統(tǒng)分析盧尚嶺教授治療頭風(fēng)病用藥經(jīng)驗(yàn)[J];中國(guó)實(shí)驗(yàn)方劑學(xué)雜志;2012年09期

5 盧朋;李健;唐仕歡;陳建新;左曉晗;劉西;溫少欣;高一波;楊洪軍;;中醫(yī)傳承輔助系統(tǒng)軟件開(kāi)發(fā)與應(yīng)用[J];中國(guó)實(shí)驗(yàn)方劑學(xué)雜志;2012年09期

6 于桂艷;黃可佳;;補(bǔ)腎法治療月經(jīng)后期臨床體會(huì)[J];遼寧中醫(yī)藥大學(xué)學(xué)報(bào);2011年06期

7 李雪琳;羅海燕;;八珍湯加味治療月經(jīng)后期30例[J];實(shí)用中醫(yī)藥雜志;2011年04期

8 于國(guó)君;;中年婦女月經(jīng)后期從肝辨治之淺見(jiàn)[J];航空航天醫(yī)學(xué)雜志;2011年03期

9 李雪琳;;自擬補(bǔ)腎養(yǎng)血調(diào)經(jīng)湯治療月經(jīng)后期40例[J];云南中醫(yī)中藥雜志;2011年03期

10 陳香梅;趙海生;;當(dāng)歸芍藥散加味應(yīng)用于月經(jīng)后期肝郁氣結(jié)證體會(huì)[J];河南中醫(yī);2011年02期

相關(guān)碩士學(xué)位論文 前1條

1 周偉;中藥方劑核心藥物及其配伍規(guī)律挖掘[D];南京大學(xué);2013年

，

本文編號(hào)：1565127