本文關(guān)鍵詞： 補腎調(diào)周法 卵巢儲備功能下降 腎陰虛型　出處：《南京中醫(yī)藥大學(xué)》2017年碩士論文　論文類型：學(xué)位論文

【摘要】：研究目的:1.討論分析夏氏補腎調(diào)周法治療腎陰虛型卵巢儲備功能下降的臨床療效及治療藥物的安全性。2.改善患者臨床癥狀,恢復(fù)正常月經(jīng),為患者維持正常的生活質(zhì)量奠定基礎(chǔ)。3.提高正常受孕及輔助生殖成功率。4.為臨床中進(jìn)一步推廣、運用提供依據(jù)。研究方法:本研究采用自身前后對照法,收集符合納入病例標(biāo)準(zhǔn)的卵巢儲備功能下降(腎陰虛型)患者30例,運用補腎調(diào)周法治療6個月。治療前與治療后相對比,研究分析患者的月信周期長短、經(jīng)量多少及中醫(yī)臨床癥狀是否有變化、變化的程度等,同時觀察血清黃體生成素(LH)、卵泡刺激素(FSH)、雌二醇(E2)、卵泡刺激素/黃體生成素(FSH/LH)比值的變化、B超變化及患者妊娠情況,來分析補腎調(diào)周法治療卵巢儲備功能下降的機理及療效。結(jié)果:1.本研究所納入30例患者,經(jīng)夏氏補腎調(diào)周法治療后,痊愈3人,比例為10.0%,顯效7人,比例為23.3%,有效17人,比例為56.7%,總有效率達(dá)90%;治療后中醫(yī)證候療效總有效率為90%,與治療前相比,統(tǒng)計有明顯差異(P0.05)。2.相比于治療前,治療6月后血清E2水平升高,FSH下降,FSH/LH比值降低,治療前后統(tǒng)計差別顯著(P0.05)。治療前后LH數(shù)值無明顯統(tǒng)計學(xué)差異(P0.05)。3.治療2個療程后中醫(yī)癥狀總積分為12.27±9.21,與治療前中醫(yī)癥狀總積分28.13±4.98對比,顯然下降(P0.05),且治療后患者經(jīng)期、經(jīng)量、腰膝酸軟、心悸耳鳴、煩躁失眠、易怒多夢及潮熱盜汗等癥均較前明顯改善,差異有統(tǒng)計學(xué)意義(P0.05)。結(jié)論夏氏補腎調(diào)周法治療腎陰虛型卵巢儲備功能低下,成效顯著。運用夏氏補腎調(diào)周法治療DOR,在促進(jìn)患者臨床癥狀向愈、生活質(zhì)量向好、性激素水平趨于平衡及月經(jīng)周期趨于正常等方面,效果突出;夏氏補腎調(diào)周法可通過調(diào)節(jié)心-腎-子宮生殖軸,來調(diào)節(jié)機體內(nèi)環(huán)境,從而達(dá)到改善卵巢功能的作用。
[Abstract]:Objective 1. To discuss and analyze the clinical effect of Xia's method of tonifying the kidney and regulating the week in the treatment of the decline of ovarian reserve function in the type of kidney yin deficiency and the safety of the medicine. 2. To improve the clinical symptoms of the patients and restore their normal menstruation. To lay a foundation for patients to maintain normal quality of life .3. to improve the success rate of normal conception and assisted reproduction. 4. To provide the basis for further promotion and application in clinical practice. Thirty patients with decreased ovarian reserve function (kidney yin deficiency type) were collected and treated for 6 months with tonifying kidney and regulating week. At the same time, the changes of serum luteinizing hormone (LHN), follicle stimulating hormone (FSH), estradiol estradiol (E2N), follicle stimulating hormone / luteinizing hormone (FSH / LH) ratio, B-mode ultrasound and pregnancy were observed. To analyze the mechanism and curative effect of tonifying kidney and regulating week in treating the decline of ovarian reserve function. Results 1. 30 patients were included in this study. 3 patients were cured after treatment with Xia's method of tonifying kidney and regulating week, the proportion was 10.0, the effect was 7, the proportion was 23.3g, and the effective was 17. The ratio was 56.7 and the total effective rate was 90. After treatment, the total effective rate of TCM syndromes was 90, compared with that before treatment, there was a significant difference between before treatment and before treatment. Compared with before treatment, the level of serum E2 increased after treatment on June, and the ratio of FSH to FSH decreased. There was no significant difference in LH value before and after treatment. The total score of TCM symptoms after two courses of treatment was 12.27 鹵9.21, which was significantly lower than that before treatment (28.13 鹵4.98). The waist and knee ache, palpitation and tinnitus, restlessness and insomnia, irritability and dreams, hot flashes and night sweats were all significantly improved, and the difference was statistically significant (P 0.05). Conclusion Xia's method of tonifying the kidney and regulating the week in the treatment of ovarian reserve function of kidney yin deficiency type is lower than that before. The effect is remarkable. The treatment of Dor with Xia's method of tonifying the kidney and regulating the week is effective in promoting the recovery of clinical symptoms, the quality of life, the balance of sex hormone level and the normal menstrual cycle. Xia's method of tonifying the kidney and regulating the week can regulate the internal environment of the body by regulating the reproductive axis of heart kidney and uterus so as to improve the function of ovary.
【學(xué)位授予單位】：南京中醫(yī)藥大學(xué)
【學(xué)位級別】：碩士
【學(xué)位授予年份】：2017
【分類號】：R271.9

【參考文獻(xiàn)】

相關(guān)期刊論文 前10條

1 李楊;高慧;徐文君;吳金洋;;中藥補腎調(diào)沖方對卵巢儲備功能低下大鼠的影響[J];亞太傳統(tǒng)醫(yī)藥;2016年18期

2 馮桂玲;李靜;周小琳;;補腎健脾方對免疫性卵巢功能衰退小鼠性激素及卵子質(zhì)量的影響[J];中醫(yī)雜志;2016年16期

3 梁玲;聶瑩;余琳;;中西醫(yī)結(jié)合治療卵巢儲備功能低下不孕患者效果分析[J];深圳中西醫(yī)結(jié)合雜志;2016年14期

4 馮桂玲;尤昭玲;熊桀;;補腎健脾法對卵巢低反應(yīng)患者基礎(chǔ)內(nèi)分泌影響的臨床研究[J];國醫(yī)論壇;2016年03期

5 錢敏;林曉平;黃東;;補腎調(diào)周法聯(lián)合激素治療卵巢儲備功能低下的臨床研究[J];中國臨床藥理學(xué)雜志;2016年06期

6 唐靜;;不同促排卵方法對卵巢儲備功能下降患者的療效[J];實用臨床醫(yī)藥雜志;2016年05期

7 張利;黃素英;;育腎調(diào)沖法治療卵巢儲備功能下降月經(jīng)過少32例[J];云南中醫(yī)學(xué)院學(xué)報;2016年01期

8 唐文龍;胡雨華;何曉華;;經(jīng)脈排刺治療陰陽兩虛型卵巢儲備功能下降的臨床研究[J];針刺研究;2015年06期

9 江麗;陳勇霞;;克羅米芬聯(lián)合重組人促黃體激素在卵巢儲備功能減退患者促排卵治療中的應(yīng)用效果[J];廣東醫(yī)學(xué);2015年19期

10 陳玉慶;朱曉銘;劉迎萍;潘文;屈紅;;二仙湯加減配合耳穴壓丸法治療卵巢儲備功能下降所致月經(jīng)后期療效觀察[J];新中醫(yī);2015年10期

，

本文編號：1536737