本文關(guān)鍵詞： 慢性阻塞性肺疾病 急性加重期 辨證論治 臨床療效　出處：《南京中醫(yī)藥大學(xué)》2017年碩士論文　論文類型：學(xué)位論文

【摘要】：目的:觀察中醫(yī)辨證組方在治療慢性阻塞性肺疾病急性加重期的臨床療效,與單用西藥治療進(jìn)行比較,總結(jié)出具有中醫(yī)藥特色并具有療效優(yōu)勢(shì)的治療方案,從而拓展慢性阻塞性肺疾病急性加重期的治療途徑,增加治療慢性阻塞性肺疾病急性加重期的方法。方法:采用隊(duì)列研究方法,將260例符合慢性阻塞性肺疾病急性加重期診斷標(biāo)準(zhǔn)的住院患者為研究對(duì)象,將患者病例分為治療組和對(duì)照組。其中對(duì)照組55例,給予西醫(yī)常規(guī)治療(吸氧、抗感染、止咳化痰、解痙平喘等)。治療組205例,在予西醫(yī)常規(guī)治療的基礎(chǔ)上,按照中醫(yī)證型(表寒里熱、痰熱蘊(yùn)肺、痰濁壅肺、肺脾兩虛、肺腎兩虛)給予中藥口服,一日兩次。觀察治療前后兩組患者總住院天數(shù)、主要癥狀、次要癥狀、臨床療效等指標(biāo),整理數(shù)據(jù)資料,并進(jìn)行統(tǒng)計(jì)學(xué)處理和分析。結(jié)果:根據(jù)病例數(shù)據(jù)統(tǒng)計(jì)結(jié)果示,兩組比較,在住院時(shí)間方面,治療組較對(duì)照組可縮短患者住院時(shí)間;在癥狀方面,在咳嗽、咳痰、胸悶、紫紺、口干、出汗等方面,治療組的癥狀改善明顯優(yōu)于對(duì)照組(P0.05);在飲食方面,治療組的改善情況優(yōu)于對(duì)照組;在喘息、氣短、哮鳴音方面,治療組和對(duì)照組的癥狀改善情況類似,無(wú)顯著差異。在實(shí)驗(yàn)室指標(biāo)方面,兩組在治療前后均有改善,在白細(xì)胞計(jì)數(shù)、中性粒細(xì)胞百分比、C反應(yīng)蛋白及血?dú)夥治鯬H、PaO2方面,兩組比較無(wú)統(tǒng)計(jì)學(xué)差異(P0.05)。在療效方面,治療組總有效率高于對(duì)照組。結(jié)論:中醫(yī)治療慢性阻塞性肺疾病急性加重期療效較單純西藥更佳,能改善患者臨床癥狀,縮短其住院天數(shù),從而改善患者的生存質(zhì)量。本課題結(jié)果表明中醫(yī)藥治療慢性阻塞性肺疾病急性加重期方面有一定優(yōu)越性,值得臨床參考和推廣。
[Abstract]:Objective: to observe the clinical effect of TCM syndrome differentiation prescription in the treatment of acute exacerbation of chronic obstructive pulmonary disease (COPD). In order to expand the treatment of acute exacerbation of chronic obstructive pulmonary disease, increase the treatment of acute exacerbation of chronic obstructive pulmonary disease. 260 inpatients who met the diagnostic criteria for acute exacerbation of chronic obstructive pulmonary disease were divided into treatment group and control group. 55 cases in control group were treated with routine western medicine treatment (oxygen inhalation, anti-infection, cough and phlegm control). Treatment group 205 cases, on the basis of routine treatment of western medicine, according to the TCM syndrome type (epiphlegm heat, phlegm heat accumulation lung, phlegm turbid obstruction of lung, deficiency of lung and spleen, deficiency of lung and kidney), oral administration of Chinese medicine. In 1st, we observed the total hospitalization days, main symptoms, secondary symptoms, clinical efficacy and other indicators of the two groups before and after the treatment, collated the data, and conducted statistical analysis. Results: according to the statistical results of the case data, In comparison between the two groups, in terms of hospitalization time, the treatment group can shorten the hospitalization time of the patients compared with the control group; in terms of symptoms, such as cough, expectoration, chest tightness, cyanosis, dry mouth, sweating, and so on, The improvement of symptoms in the treatment group was significantly better than that in the control group (P 0.05); in the diet, the improvement in the treatment group was better than that in the control group; in terms of wheezing, shortness of breath and wheezing, the improvement of symptoms in the treatment group and the control group was similar. There was no significant difference in laboratory indexes between the two groups before and after treatment. There was no significant difference in white blood cell count, percentage of neutrophil C-reactive protein and blood gas analysis between the two groups (P 0.05). The total effective rate of the treatment group is higher than that of the control group. Conclusion: the curative effect of traditional Chinese medicine on acute exacerbation of chronic obstructive pulmonary disease is better than that of western medicine alone, which can improve the clinical symptoms of the patients and shorten their hospitalization days. So as to improve the quality of life of patients. The results show that TCM treatment of acute exacerbation of chronic obstructive pulmonary disease has some advantages, and is worthy of clinical reference and promotion.
【學(xué)位授予單位】：南京中醫(yī)藥大學(xué)
【學(xué)位級(jí)別】：碩士
【學(xué)位授予年份】：2017
【分類號(hào)】：R259

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本文編號(hào)：1534048