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育陰止崩湯治療陰虛血熱型月經(jīng)過多的臨床觀察

發(fā)布時(shí)間:2018-02-16 04:47

  本文關(guān)鍵詞: 月經(jīng)過多 育陰止崩湯 陰虛血熱型 出處:《福建中醫(yī)藥大學(xué)》2016年碩士論文 論文類型:學(xué)位論文


【摘要】:目的:本課題探討育陰止崩湯對(duì)陰虛血熱型月經(jīng)過多患者的影響,并與西藥氨甲環(huán)酸片對(duì)照,觀察治療后患者月經(jīng)失血量、血紅蛋白含量、月經(jīng)過多特異性生存質(zhì)量(包括經(jīng)期活動(dòng)受限、經(jīng)期疲倦、經(jīng)期煩躁、經(jīng)期情緒低落程度受累評(píng)分及時(shí)間受累評(píng)分)、子宮內(nèi)膜厚度、遠(yuǎn)期調(diào)經(jīng)療效以及中醫(yī)癥狀改善的情況。對(duì)育陰止崩湯治療陰虛血熱型月經(jīng)過多臨床療效進(jìn)行客觀的評(píng)價(jià),為月經(jīng)過多中醫(yī)辨證專方的研究提供客觀依據(jù)。方法:選取福建中醫(yī)藥大學(xué)附屬人民醫(yī)院婦科門診患者60例,按隨機(jī)數(shù)字表法分為治療組30例和對(duì)照組30例,治療組予中藥育陰止崩湯,對(duì)照組予氨甲環(huán)酸,觀察比較育陰止崩湯和氨甲環(huán)酸在治療前與治療后對(duì)月經(jīng)失血量評(píng)分、血紅蛋白含量、生存質(zhì)量、子宮內(nèi)膜厚度、遠(yuǎn)期調(diào)經(jīng)療效以及中醫(yī)癥狀情況。通過對(duì)比,以期對(duì)育陰止崩湯治療陰虛血熱型月經(jīng)過多臨床療效進(jìn)行客觀的評(píng)價(jià)。結(jié)果:1.治療組總有效率86.67%;對(duì)照組總有效率83.33%。兩組患者綜合療效比較,差異無統(tǒng)計(jì)學(xué)意義(P0.05),表明兩組綜合療效相當(dāng)。2.兩組治療后與各自治療前癥狀總積分比較,均有顯著性差異(P0.05);兩組患者治療后組間癥狀總積分比較,差異有統(tǒng)計(jì)學(xué)意義(P0.05);治療后兩組患者中醫(yī)證候療效比較,差異有統(tǒng)計(jì)學(xué)意義(P0.05),提示治療組在改善中醫(yī)癥狀方面優(yōu)于對(duì)照組。3.兩組治療后與各自治療前月經(jīng)失血量比較,均有顯著差異(P0.05);治療后兩組組間月經(jīng)失血量比較無顯著差異(P0.05),說明兩組改善月經(jīng)失血量方面效果相當(dāng)。4.兩組治療后月經(jīng)過多特異性生存質(zhì)量評(píng)分(包括經(jīng)期活動(dòng)受限、經(jīng)期疲倦、經(jīng)期煩躁、經(jīng)期情緒低落程度受累評(píng)分及時(shí)間受累評(píng)分)與各自治療前比較,均有顯著性差異(P0.05);治療后兩組組間比較差異無統(tǒng)計(jì)學(xué)意義(P0.05),表明育陰止崩湯在改善月經(jīng)過多特異性生存質(zhì)量方面與對(duì)照組相當(dāng)。5.兩組治療后血紅蛋白含量與各自治療前對(duì)比,均有顯著差異(P0.05);治療后兩組組間比較,差異有統(tǒng)計(jì)學(xué)意義(P0.05),表明治療組在改善血紅蛋白含量方面優(yōu)于對(duì)照組。6.治療組治療前后子宮內(nèi)膜厚度有顯著性差異(P0.05),對(duì)照組治療前后無顯著性差異(P0.05),治療后治療組及對(duì)照組子宮內(nèi)膜厚度比較有顯著差異(P0.05)。說明治療組改善子宮內(nèi)膜厚度。7.兩組比較隨訪3個(gè)月經(jīng)周期的調(diào)經(jīng)療效,差異有統(tǒng)計(jì)學(xué)意義(P0.05),表明育陰止崩湯在隨訪3個(gè)月經(jīng)周期的調(diào)經(jīng)療效方面優(yōu)于對(duì)照組。結(jié)論:運(yùn)用育陰止崩湯治療陰虛血熱型月經(jīng)過多,能明顯改善中醫(yī)癥狀,減少月經(jīng)失血量.改善月經(jīng)過多特異性生存質(zhì)量,提高血紅蛋白含量,有效改善子宮內(nèi)膜厚度,能鞏固調(diào)整月經(jīng)療效。且無明顯不良反應(yīng),顯示了中醫(yī)辨證治療本病的優(yōu)越性,為陰虛血熱型月經(jīng)過多中醫(yī)辨證專方的研究提供客觀依據(jù)。
[Abstract]:Objective: to investigate the effect of Yuyin Zhibong decoction on menorrhagia of yin deficiency and blood heat type, and to observe the amount of menorrhagia and the content of hemoglobin in patients with menorrhagia after treatment. Menstrual specific quality of life (including menstrual activity restriction, menstrual fatigue, menstrual irritability, menstrual depression and time involvement score, endometrial thickness, The long-term effect of regulating menstruation and the improvement of TCM symptoms. Objective evaluation was made on the clinical efficacy of Yuyin Zhibong decoction in treating menorrhagia of Yin-deficiency and blood-heat type. Methods: 60 gynecological outpatients of people's Hospital affiliated to Fujian University of traditional Chinese Medicine were selected and randomly divided into treatment group (30 cases) and control group (30 cases). The treatment group was treated with Yuyin Zhibong decoction, while the control group was treated with carbamate. The blood loss score, hemoglobin content, quality of life and endometrial thickness before and after treatment were observed and compared between the treatment group and the control group. Long-term effects of menstrual regulation and symptoms of traditional Chinese medicine. Through comparison, Results: 1. The total effective rate of the treatment group was 86.677.The total effective rate of the control group was 83.33.The comprehensive curative effect of the two groups was compared. There was no significant difference between the two groups (P 0.05), which indicated that the comprehensive curative effect of the two groups was equivalent. 2. There was significant difference in the total score of symptoms between the two groups after treatment and before treatment, and there was a significant difference in the total score of symptoms between the two groups after treatment, and there was a significant difference between the two groups in the total score of symptoms after treatment. The difference was statistically significant (P 0.05), and the difference between the two groups after treatment was statistically significant (P 0.05), suggesting that the treatment group was superior to the control group in improving the symptoms of traditional Chinese medicine. The amount of menstrual blood loss in the two groups after treatment was higher than that in the control group before and after treatment. There was no significant difference in menstrual blood loss between the two groups after treatment, which indicated that the two groups had the same effect in improving menstrual blood loss. 4. The specific quality of life score (including limited menstrual activity) in the two groups after treatment. Menstrual fatigue, menstrual irritability, menstrual depression degree of involvement score and time involvement score) compared with their pre-treatment, There was no significant difference between the two groups after treatment (P 0.05), which indicated that Yuyin Zhibong decoction was comparable to the control group in improving the quality of life of menstrual hypertrophy. The hemoglobin content of the two groups was compared with that of the control group before and after treatment. There were significant differences between the two groups after treatment. The difference was statistically significant (P 0.05), which indicated that the treatment group was superior to the control group in improving hemoglobin content. 6. There was a significant difference in endometrial thickness before and after treatment in the treatment group, but there was no significant difference in the endometrial thickness in the control group before and after treatment (P 0.05). There was a significant difference in endometrial thickness between the two groups (P 0.05), which indicated that the treatment group improved endometrial thickness. 7. The two groups were followed up for 3 menstrual cycles. The difference was statistically significant (P 0.05), which indicated that Yuyin Zhibong decoction was superior to the control group in regulating menstruation in three menstrual cycles. Conclusion: Yuyin Zhibong decoction can obviously improve the symptoms of traditional Chinese medicine in treating menorrhagia of yin deficiency and blood heat type. Reduce the amount of menstrual bleeding, improve the specific quality of life of menstruation, increase the content of hemoglobin, effectively improve the thickness of endometrium, can consolidate and adjust menstrual efficacy, and there is no obvious adverse reactions, showing the advantages of TCM syndrome differentiation treatment of this disease, To provide an objective basis for the study of TCM syndrome differentiation prescription for menstruation with yin deficiency and blood heat.
【學(xué)位授予單位】:福建中醫(yī)藥大學(xué)
【學(xué)位級(jí)別】:碩士
【學(xué)位授予年份】:2016
【分類號(hào)】:R271.111

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