本文關(guān)鍵詞： 慢性阻塞性肺疾病 穩(wěn)定期 加味六君子湯 肺功能 CAT評分 急性加重次數(shù) 體重指數(shù)　出處：《湖南中醫(yī)藥大學》2016年碩士論文　論文類型：學位論文

【摘要】：目的:通過觀察加味六君子湯對慢性阻塞性肺疾病穩(wěn)定期肺脾氣虛證患者的臨床療效及安全性,為臨床治療慢性阻塞性肺疾病穩(wěn)定期提供更多的臨床依據(jù)。方法:將符合納入標準的60例慢性阻塞性肺疾病穩(wěn)定期肺脾氣虛證患者,采用隨機數(shù)字表法分為兩組,治療組和對照組各30例。對照組采用西醫(yī)常規(guī)治療,給予低流量吸氧、噻托溴銨吸入及解痙平喘治療;治療組在對照組的基礎上,加用加味六君子湯口服(每日一劑,早晚分服);療程為12周,隨訪1年。觀察兩組患者治療前后臨床癥狀及體征、總體證候積分、肺功能、CAT評分、體重指數(shù)及急性加重次數(shù)的變化。結(jié)果:1.加味六君子湯治療慢性阻塞性肺疾病穩(wěn)定期肺脾氣虛證患者,與對照組相比,在減輕癥狀(咳嗽、咳痰、喘息、納呆、腹脹、自汗、易感冒等)和體征(Up音)的證候總積分上,總的治療效果治療組優(yōu)于對照組(P0.05)。2.兩組均能提高患者肺功能FEV1%,差異具有統(tǒng)計學意義(P0.05)。但治療后治療組與對照組組間比較肺功能FEV1%差異無統(tǒng)計學意義(P0.05)。3.加味六君子湯治療慢阻肺穩(wěn)定期肺脾氣虛證患者,與對照組相比,可明顯提高患者的體重指數(shù),降低CAT評分,減少急性加重次數(shù)(P0.05)。結(jié)論:加味六君子湯可改善慢性阻塞性肺疾病穩(wěn)定期肺脾氣虛證患者總的臨床癥狀和體征,提高總有效率;可改善患者肺功能FEV1%水平,改善情況與西藥常規(guī)治療無明顯差異;可提高患者體重指數(shù),改善慢性阻塞性肺疾病患者后期營養(yǎng)不良的狀況,同時還可改善患者CAT評分,減少急性加重次數(shù),提高患者生活質(zhì)量,改善預后。
[Abstract]:Objective: to observe the clinical efficacy and safety of Jiawei Liujunzi decoction in the treatment of chronic obstructive pulmonary disease (COPD) with stable lung qi deficiency syndrome. Methods: 60 patients with chronic obstructive pulmonary disease at stable stage were divided into two groups by random digital table. The treatment group and the control group each had 30 cases. The control group was treated with routine western medicine, received low-flow oxygen inhalation, tiotropium bromide inhalation and antispasmolysis therapy, while the treatment group was treated with Jiawei Liujunzi decoction orally (one dose per day) on the basis of the control group. The course of treatment was 12 weeks and followed up for one year. The clinical symptoms and signs, total syndromes score, pulmonary function cat score before and after treatment were observed in both groups. Changes of body mass index and acute exacerbation times. Results: 1. Jiawei Liujunzi decoction was used to treat chronic obstructive pulmonary disease (COPD) patients with chronic obstructive pulmonary disease (COPD) during stable stage of deficiency of the lung. Compared with the control group, the patients were relieved of symptoms (cough, expectoration, wheezing, insufflation, abdominal distension, self-sweating). On the total score of syndromes and signs. The total therapeutic effect in the treatment group was better than that in the control group (P 0.05 .2.). Both groups could improve the pulmonary function of the patients with FEV1, the difference was statistically significant, but there was no significant difference in FEV1% between the treatment group and the control group after treatment. The decoction is used to treat the patients with deficiency of the lung in the stable period of chronic obstructive lung. Compared with the control group, it can significantly increase the body mass index, reduce the CAT score and reduce the acute exacerbation times (P0.050.Conclusion: the modified Liujunzi decoction can improve the total clinical symptoms and signs of chronic obstructive pulmonary disease patients with stable lung temper deficiency syndrome. Improving the total effective rate, improving the FEV1% level of pulmonary function of the patients, and improving the state of the patients with chronic obstructive pulmonary disease (COPD) were not significantly different from the routine treatment of western medicine, and could increase the body mass index of the patients and improve the malnutrition of the patients with chronic obstructive pulmonary disease (COPD) in the later stage. At the same time, it can improve the CAT score, reduce the times of acute exacerbation, improve the quality of life and improve the prognosis.
【學位授予單位】：湖南中醫(yī)藥大學
【學位級別】：碩士
【學位授予年份】：2016
【分類號】：R259

【參考文獻】

相關(guān)期刊論文 前10條

1 張燦輝;焦維克;鄧新宇;薛青;甘玉燕;王陳金;;福建省寧德市農(nóng)村40歲以上畬族人群慢性阻塞性肺疾病的流行病學調(diào)查[J];中國慢性病預防與控制;2016年02期

2 王莉;;慢性阻塞性肺疾病、合并癥的臨床分析[J];世界最新醫(yī)學信息文摘;2016年01期

3 張高;孫志佳;褚慶民;;補肺健脾益腎法對早期慢性阻塞性肺疾病穩(wěn)定期干預作用[J];遼寧中醫(yī)藥大學學報;2015年12期

4 王連紅;羅倩;張莉;;遵義地區(qū)2014年慢性阻塞性肺疾病患者疾病費用分析[J];貴州醫(yī)藥;2015年11期

5 曹福凱;郭建輝;何嘉;宋德胤;;健脾益肺口服液對慢性阻塞性肺疾病肺脾氣虛證患者生存質(zhì)量的影響[J];中醫(yī)學報;2015年11期

6 李建;馮芮華;崔月穎;劉雙梅;曾昭媛玲;王小萬;;我國三級醫(yī)院藥物治療慢阻肺患者的經(jīng)濟負擔分析[J];中國衛(wèi)生經(jīng)濟;2015年09期

7 萬芳竹;李媛媛;崔德芝;;慢性阻塞性肺疾病營養(yǎng)不良的研究進展[J];山東醫(yī)藥;2015年29期

8 陳振平;劉學芬;;健脾益肺湯治療肺脾氣虛型慢性阻塞性肺疾病臨床研究[J];中醫(yī)學報;2015年06期

9 王振偉;楊佩蘭;沈麗;湯杰;;百部養(yǎng)肺煎膏治療COPD穩(wěn)定期患者的臨床研究[J];西部中醫(yī)藥;2015年05期

10 周建龍;鄧青南;梁靜;;半夏提取物對小鼠肺水通道蛋白5表達的影響[J];長春中醫(yī)藥大學學報;2015年02期

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