獨活寄生湯聯(lián)合刺絡(luò)放血法治療老年膝關(guān)節(jié)炎臨床療效及安全性研究
發(fā)布時間:2018-01-22 19:05
本文關(guān)鍵詞: 獨活寄生湯 刺絡(luò)放血法 老年膝關(guān)節(jié)炎 出處:《遼寧中醫(yī)雜志》2017年02期 論文類型:期刊論文
【摘要】:目的:探討?yīng)毣罴纳鷾?lián)合刺絡(luò)放血法治療老年膝關(guān)節(jié)炎的臨床療效及安全性。方法:研究對象病例均為本院診斷及治療的老年膝關(guān)節(jié)炎患者112例,按隨機(jī)數(shù)字表法分組,對照組56例予以西醫(yī)治療;研究組56例予以獨活寄生湯聯(lián)合刺絡(luò)放血法治療,評定WOMAC疼痛量表評分,檢測血清及關(guān)節(jié)液細(xì)胞因子變化,同時對比臨床療效及并發(fā)癥。結(jié)果:對照組臨床有效率76.79%與研究組臨床有效率91.07%數(shù)據(jù)對比,有差異(P0.05);相對于治療前,兩組治療后疼痛評分、關(guān)節(jié)僵硬評分、生理功能評分及總分均顯著降低,治療后血清及關(guān)節(jié)液IL-1、TNF-α水平均降低,關(guān)節(jié)液CTX-Ⅱ水平均升高,有差異(P0.05);相對于對照組,研究組治療后疼痛評分、關(guān)節(jié)僵硬評分、生理功能評分較低,治療后血清及關(guān)節(jié)液IL-1、TNF-α較低,關(guān)節(jié)液CTX-Ⅱ較高,有差異(P0.05)。結(jié)論:獨活寄生湯聯(lián)合刺絡(luò)放血法治療老年膝關(guān)節(jié)炎療效顯著,能降低炎癥指標(biāo),提高膝關(guān)節(jié)活動功能。
[Abstract]:Objective: to investigate the clinical efficacy and safety of Duhuzhitang combined with pricking and bleeding in treating senile knee arthritis. Methods: 112 cases of senile knee arthritis diagnosed and treated in our hospital were studied. According to the method of random digital table, 56 cases in the control group were treated with western medicine. 56 cases in the study group were treated with Duhuzhitang combined with pricking and bleeding method to evaluate the score of WOMAC pain scale and to detect the changes of cytokines in serum and joint fluid. Results: the clinical effective rate of the control group (76.79%) was compared with that of the study group (91.07%). Compared with before treatment, the pain score, joint stiffness score, physiological function score and total score were significantly decreased in both groups, and the levels of IL-1TNF- 偽 in serum and joint fluid were all decreased after treatment. The level of CTX- 鈪,
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