發(fā)布時(shí)間：2018-01-22 03:26

  本文關(guān)鍵詞： 防風(fēng)消癮湯 蕁麻疹 胃腸濕熱 幽門螺桿菌 臨床觀察　出處：《黑龍江中醫(yī)藥大學(xué)》2017年碩士論文　論文類型：學(xué)位論文

【摘要】：目的:觀察防風(fēng)消癮湯治療胃腸濕熱型蕁麻疹的臨床療效;并探討蕁麻疹的發(fā)病與幽門螺桿菌感染之間的關(guān)系。方法:選取符合納入標(biāo)準(zhǔn)蕁麻疹患者78例,對(duì)照組脫落2例(2例患者均因故中止研究而剔除),最終76例完成臨床觀察,采用隨機(jī)對(duì)照研究方法,按就診先后順序隨機(jī)分為治療組和對(duì)照組,治療組39例,對(duì)照組37例。治療組運(yùn)用防風(fēng)消癮湯治療,對(duì)照組口服鹽酸依匹斯汀膠囊和西咪替丁片。觀察6周,每隔2周復(fù)診一次,分別在2、4、6周各觀察一次,記錄癥狀積分情況,6周后統(tǒng)計(jì)積分并判定療效,檢測(cè)Hp值。觀察結(jié)束后,隔6周做一次隨訪,記錄復(fù)發(fā)情況,判斷遠(yuǎn)期療效。結(jié)果:1、治療6周后兩組患者總有效率對(duì)比:治療組總有效率為85.17%,對(duì)照組總有效率為54.04%。兩組總有效率比較,經(jīng)秩和檢驗(yàn),P0.05,有顯著性差異,結(jié)果有統(tǒng)計(jì)學(xué)意義。提示治療組療效優(yōu)于對(duì)照組,防風(fēng)消癮湯能明顯改善蕁麻疹患者的風(fēng)團(tuán)癥狀和瘙癢程度。2、通過與我院健康體檢者作對(duì)比,慢性蕁麻疹患者中幽門螺桿菌感染率明顯高于健康對(duì)照組。治療結(jié)束后6周隨訪觀察,統(tǒng)計(jì)復(fù)發(fā)率,治療組蕁麻疹復(fù)發(fā)7例,復(fù)發(fā)率20.59%,對(duì)照組復(fù)發(fā)9例,復(fù)發(fā)率45%。治療組復(fù)發(fā)率明顯低于對(duì)照組,防風(fēng)消癮湯治療蕁麻疹有較好的遠(yuǎn)期療效。結(jié)論:1、防風(fēng)消癮湯治療胃腸濕熱型蕁麻疹療效顯著;副作用小、復(fù)發(fā)率低,是治療胃腸濕熱型蕁麻疹的有效方劑。2、治療組防風(fēng)消癮湯治療伴有幽門螺桿菌感染的慢性蕁麻疹療效優(yōu)于對(duì)照組口服鹽酸依匹斯汀膠囊和西咪替丁片。
[Abstract]:Objective: To observe the clinical curative effect of eliminating wind addiction Decoction in the treatment of gastrointestinal damp heat urticaria; and to explore the relationship between the pathogenesis of urticaria and Helicobacter pylori infection. Methods: 78 cases met the inclusion criteria of patients with urticaria, 2 cases of the control group. (2 cases were excluded, security for Research) finally 76 patients completed clinical observation, a randomized controlled trial, patients were randomly divided into treatment group and control group, 39 cases in the treatment group, 37 cases in the control group. The treatment group used wind fire addiction decoction, control group was treated with Epinastine Hydrochloride Capsules and Cimetidine Tablets. After 6 weeks, every 2 weeks once, respectively in 2,4,6 week observation time, record the symptom integral situation, after 6 weeks of statistical integral and judge the effect, the detection of Hp value. After the observation, every 6 weeks for a follow-up record, recurrence, determine the long-term curative effect. Results: 1, after 6 weeks of treatment, two groups of patients Efficiency comparison: treatment group total effective rate was 85.17%, the total efficiency of the control group 54.04%. total efficiency of two groups, the rank and inspection, P0.05, there are significant differences, the results have statistical significance. Conclusion the curative effect of the treatment group than the control group, the wind fire addiction decoction can obviously improve the symptoms of urticaria urticaria.2 and the degree of itching, through the comparison with our hospital health examination. The rate was significantly higher than the control group of Helicobacter pylori infection in patients with chronic urticaria. 6 weeks after treatment, recurrence rate of treatment group, 7 cases of recurrent urticaria, the recurrence rate was 20.59%, control group 9 cases of recurrence, the recurrence rate of 45%. group the recurrence rate was significantly lower than the control group, the wind fire has better long-term effects of addiction Decoction in the treatment of urticaria. Conclusion: 1. The effect of eliminating wind addiction Decoction in the treatment of gastrointestinal damp heat urticaria significantly; small side effect, low recurrence rate, is the treatment of gastrointestinal damp heat urticaria The effective prescription of.2, the treatment group is better than the wind dissipation of chronic urticaria with addiction Decoction in the treatment of Helicobacter pylori infection in control group were treated with Epinastine Hydrochloride Capsules and Cimetidine Tablets.

【學(xué)位授予單位】：黑龍江中醫(yī)藥大學(xué)
【學(xué)位級(jí)別】：碩士
【學(xué)位授予年份】：2017
【分類號(hào)】：R275.9

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