本文關(guān)鍵詞：小兒病毒性上呼吸道感染采用小兒豉翹清熱顆粒治療療效觀察　出處：《中華中醫(yī)藥學刊》2017年05期 　論文類型：期刊論文

  更多相關(guān)文章： 小兒豉翹清熱顆粒 小兒病毒性上呼吸道感染 利巴韋林顆粒 退熱 血清指標

【摘要】：目的:探討小兒病毒性上呼吸道感染采用小兒豉翹清熱顆粒治療療效。方法:截選2015年1月—2016年1月86例小兒病毒性上呼吸道感染患者按照隨機數(shù)字表法分組為對照組[利巴韋林顆粒,10 mg/(kg·d),分2~3次服用]與治療組(小兒豉翹清熱顆粒,6個月~1歲,1~2 g/次,1~3歲,2~3 g/次,3~7歲,3~4 g/次;均為3次/d),各43例。記錄兩組患兒開始退熱時間、完全退熱時間,統(tǒng)計兩組臨床療效及不良反應,并評價兩組患兒治療前、后中醫(yī)證候積分變化;檢測兩組患兒治療前、后血清腫瘤壞死因子α(TNF-α)、白細胞介素-6(IL-6)水平。結(jié)果:治療組患兒開始退熱時間、完全退熱時間分別為(5.49±4.13)h、(9.20±3.75)h明顯短于對照組(22.14±8.67)h、(25.48±12.25)h,P0.05;兩組患兒治療后血清TNF-α、IL-6水平及中醫(yī)證候積分明顯低于治療前,治療組治療后血清TNF-α、IL-6水平及中醫(yī)證候積分明顯低于對照組,P0.05。治療組治療總有效率86.05%,明顯高于對照組58.14%,P0.05。治療期間均無嚴重性不良反應,未影響本次研究結(jié)果。結(jié)論:采用小兒豉翹清熱顆粒治療小兒病毒性上呼吸道感染療效顯著且安全,可推薦為患兒治療首選藥物。
[Abstract]:Objective: to investigate the therapeutic effect of infantile viral upper respiratory tract infection with Xiaojiajiaoqingre granule. 86 children with viral upper respiratory tract infection from January 2015 to January 2016 were divided into control group according to random number table. [Ribavirin granules, 10 mg/(kg 路dg, were taken twice and 3 times) and treated with the treatment group (Xiaojiaokao Qingre granules, 6 months old, 1 year old, 1g / time, 1 year old, 2g / d), and treatment group (6 months old, 1 year old, 1 year old, 1 year old, 1 year old, 3 g / time). The age of 7 years old was 3g / time; All of them were 3 times / d, 43 cases each. The time of beginning and complete antipyrexia of the two groups was recorded, the clinical curative effect and adverse reaction of the two groups were counted, and the changes of TCM syndromes integral before and after treatment were evaluated. The serum levels of TNF- 偽 and IL-6 were measured before and after treatment in both groups. Results: the antipyretic time was observed in the treatment group. The total antipyretic time was 5.49 鹵4.13 h (9.20 鹵3.75 h), significantly shorter than that in the control group (22.14 鹵8.67 h, 25.48 鹵12.25 h). P0.05; The serum TNF- 偽 IL-6 level and TCM syndromes score were significantly lower in the two groups after treatment than before, and the serum TNF- 偽 after treatment in the treatment group. IL-6 level and TCM syndrome score were significantly lower than that of control group P0.05.The total effective rate of treatment group was 86.05, which was significantly higher than that of control group (58.14%). P0.05. there were no serious adverse reactions during the treatment, which did not affect the results of this study. Conclusion: the treatment of infantile viral upper respiratory tract infection with Xiaojiajiaoqingre granule is effective and safe. It can be recommended as the first choice in the treatment of children.
【作者單位】： 溫州醫(yī)科大學附屬第三醫(yī)院兒科;溫州醫(yī)科大學附屬第三醫(yī)院中醫(yī)兒科;
【分類號】：R272
【正文快照】： 急性上呼吸道感染主要是由各種病原菌所致喉部以上鼻和鼻咽及咽部的急性炎癥,該疾病大約90.0%為病毒所致,常累及鄰近器官和淋巴結(jié)等[1]。小兒病毒性上呼吸道感染是兒童時期常見疾病,目前臨床西醫(yī)主要以多飲水和休息及增強抵抗力等為主,尚無理想治療藥物。中醫(yī)認為小兒病毒性上

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