本文關鍵詞：穴位埋線與毫針刺治療慢性疲勞綜合征（肝郁脾虛型）臨床對比觀察　出處：《湖南中醫(yī)藥大學》2016年碩士論文　論文類型：學位論文

  更多相關文章： 慢性疲勞綜合征 肝郁脾虛 穴位埋線 毫針刺 皮質(zhì)醇

【摘要】：目的:觀察和比較穴位埋線與毫針刺治療慢性疲勞綜合征肝郁脾虛型患者的臨床療效與作用特點,并初步探討其可能的作用機制,為臨床應用提供客觀依據(jù)。方法:將符合納入標準的60例患者隨機分為A組和B組,每組各30例。A組用穴位埋線,B組用毫針刺治療。兩組患者均選取肝俞、足三里、膈俞為第一組穴,脾俞、三陰交、膽俞為第二組穴,兩組穴位交替應用。A組每隔10天埋線1次,共治療4次;B組連續(xù)治療8天,休息2天為1個治療周期,共治療4個周期。治療前后用疲勞量表(FS-14)、疲勞癥狀積分量表、肝郁脾虛證候積分量表,分別對疲勞主癥、疲勞兼癥、中醫(yī)癥候三個主觀指標進行評價,并抽取靜脈血,用化學發(fā)光法檢測客觀指標即兩組患者外周血血清中皮質(zhì)醇含量。結(jié)果:1.治療后,兩組患者的FS-14評分較治療前均有下降,差異有顯著統(tǒng)計學意義(P0.01);A組較B組下降更明顯,差異有統(tǒng)計學意義(P0.05)。2.治療后,兩組患者的疲勞癥狀積分量表評分較治療前均有明顯下降,差異有顯著統(tǒng)計學意義(P0.01);A組與B組比較,差異不明顯(P0.05)。3.治療后,兩組患者的肝郁脾虛證候積分量表評分較治療前下降,差異有顯著統(tǒng)計學意義(P0.01);但兩組比較,無明顯差異(P0.05)。4.治療后兩組總療效差異無統(tǒng)計學意義(P0.05)。5.治療后,兩組患者血清皮質(zhì)醇含量較治療前有明顯增高,差異有顯著統(tǒng)計學意義(P0.01);兩組間差異不明顯,無統(tǒng)計學意義(P0.05)。結(jié)論:穴位埋線和毫針剌治療CFS肝郁脾虛型都有明顯效果,能顯著改善患者的疲勞主癥、兼癥及肝郁脾虛癥狀,但穴位埋線對改善疲勞主癥有明顯的優(yōu)勢,而且治療次數(shù)少,時間成本低,臨床可優(yōu)先選用。同時,兩者都能顯著升高CFS肝郁脾虛型患者血清中皮質(zhì)醇的含量,說明其作用機制都可能與改善神經(jīng)內(nèi)分泌系統(tǒng)中的HPA軸功能有密切關系,值得進一步研究。
[Abstract]:Objective: to observe and compare the clinical effect and characteristics of acupoint catgut embedding and millimeter acupuncture in treating chronic fatigue syndrome patients with liver depression and spleen deficiency, and to explore its possible mechanism. Methods: 60 patients who met the inclusion criteria were randomly divided into group A and group B with 30 cases in each group. Two groups of patients were selected Gangshu, Zusanli, Geshu as the first point, spleen Yu, Sanyinjiao, Danshu as the second point, and the two groups were alternately treated with catgut embedding once every 10 days. A total of 4 times of treatment; Group B was treated continuously for 8 days, rest for 2 days for a treatment cycle, a total of 4 cycles. Before and after treatment, fatigue scale FS-14, fatigue symptom scale, liver stagnation and spleen deficiency syndrome integral scale. The main symptoms of fatigue, fatigue and symptoms, TCM symptoms of the evaluation of three subjective indicators, and the extraction of venous blood. Chemiluminescence method was used to detect the content of cortisol in peripheral blood of the two groups. Results: 1. After treatment, the FS-14 scores of the two groups were lower than those before treatment. The difference was statistically significant (P 0.01). Group A than group B more significant decline, the difference was statistically significant (P 0.05). After treatment, the two groups of patients' fatigue symptom scale scores were significantly lower than before treatment. The difference was statistically significant (P 0.01). There was no significant difference between group A and group B. after treatment, the score of liver depression and spleen deficiency syndrome in two groups was lower than that before treatment, and the difference was statistically significant (P 0.01). However, there was no significant difference between the two groups (P 0.05). 4. There was no significant difference in the total curative effect between the two groups after treatment. The serum cortisol content in the two groups was significantly higher than that before treatment, and the difference was statistically significant (P 0.01). There was no significant difference between the two groups (P 0.05). Conclusion: the treatment of CFS liver stagnation and spleen deficiency type by acupuncture at acupoint and acupuncture has obvious effect, and can significantly improve the main fatigue of patients. Both symptoms and liver stagnation and spleen deficiency symptoms, but acupoint embedding has obvious advantages in improving the main fatigue syndrome, and less times of treatment, low time cost, clinical can be selected first. At the same time. Both of them could significantly increase the content of cortisol in the serum of CFS patients with liver stagnation and spleen deficiency, indicating that the mechanism may be closely related to the improvement of HPA axis function in the neuroendocrine system, which is worthy of further study.
【學位授予單位】：湖南中醫(yī)藥大學
【學位級別】：碩士
【學位授予年份】：2016
【分類號】：R246

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