本文關(guān)鍵詞：復(fù)方澤漆沖劑聯(lián)合走罐療法治療斑塊型銀屑病的療效觀察　出處：《安徽中醫(yī)藥大學(xué)》2016年碩士論文　論文類型：學(xué)位論文

  更多相關(guān)文章： 斑塊型銀屑病 復(fù)方澤漆沖劑 走罐療法 療效觀察

【摘要】：1目的探討復(fù)方澤漆沖劑聯(lián)合走罐療法治療靜止期斑塊型銀屑病的有效性及安全性,綜合評(píng)價(jià)復(fù)方澤漆沖劑聯(lián)合走罐療法的臨床價(jià)值,以便后期臨床推廣。2方法將62例符合納入標(biāo)準(zhǔn)的斑塊型銀屑病患者按隨機(jī)數(shù)字表法分為治療組和對(duì)照組,兩組各31例。治療組予復(fù)方澤漆沖劑口服,外用凡士林軟膏,同時(shí)在皮損部位進(jìn)行走罐療法。對(duì)照組予復(fù)方澤漆沖劑口服加凡士林軟膏外用。2周為1療程,共治療4個(gè)療程。治療2周后、4周后、6周后、8周后分別進(jìn)行PASI評(píng)分及瘙癢程度評(píng)分,并于療程結(jié)束后比較兩組患者皮損單項(xiàng)體征嚴(yán)重程度評(píng)分、中醫(yī)證候評(píng)分、DLQI評(píng)分、疾病療效,同時(shí)觀察整個(gè)研究過(guò)程中有無(wú)不良反應(yīng)。3結(jié)果3.1本研究療程結(jié)束后,治療組有1人因工作外調(diào)無(wú)法嚴(yán)格按照就診時(shí)間來(lái)院就診,對(duì)照組有1人在治療期間服用其他藥物,故脫落2人,最終有60例患者完成臨床研究療程,兩組各30例。兩組治療前皮損單項(xiàng)體征嚴(yán)重程度評(píng)分、PASI評(píng)分、瘙癢程度評(píng)分、中醫(yī)證候評(píng)分、DLQI評(píng)分均無(wú)統(tǒng)計(jì)學(xué)差異(P值均大于0.05),具有可比性。3.2比較兩組患者皮損單項(xiàng)體征嚴(yán)重程度評(píng)分,與各自治療前相比,治療組與對(duì)照組均能改善皮損鱗屑、浸潤(rùn)、紅斑體征(P均小于0.05);兩組組間比較,治療組在改善皮損鱗屑體征方面優(yōu)于對(duì)照組(P值等于0.006),兩組在改善皮損浸潤(rùn)及紅斑體征方面療效相當(dāng)(P值均大于0.05)。3.3兩組患者治療2周后、4周后、6周后、8周后PASI評(píng)分分別與各自治療前比較,均有統(tǒng)計(jì)學(xué)差異(P值均小于0.05),治療組與對(duì)照組均能降低患者PASI評(píng)分;從治療4周后,兩組間比較,P值均小于0.05,這說(shuō)明,從治療4周后,治療組的在降低患者PASI評(píng)分方面優(yōu)于對(duì)照組。3.4兩組患者治療2周后、4周后、6周后、8周后的瘙癢程度評(píng)分分別與各自治療前比較,均有統(tǒng)計(jì)學(xué)差異(P值均小于0.05),治療組與對(duì)照組均能改善患者瘙癢癥狀;從治療4周后,兩組間比較P值均小于0.05,這說(shuō)明,從治療4周后,治療組在改善患者瘙癢癥狀方面優(yōu)于對(duì)照組。3.5比較兩組患者治療前后中醫(yī)證候評(píng)分,與各自治療前相比,治療組與對(duì)照組均能改善斑塊型銀屑病患者血瘀癥狀(P值均小于0.05);兩組組間比較,治療組改善血瘀癥狀的療效優(yōu)于對(duì)照組(P值等于0.015)。3.6比較兩組患者治療前后DLQI評(píng)分,與各自治療前相比,治療組與對(duì)照組均能改善斑塊型銀屑病患者的生活質(zhì)量(P值均小于0.05);兩組組間比較,治療組改善斑塊型銀屑病患者的生活質(zhì)量的療效優(yōu)于對(duì)照組(P值等于0.006)。3.7比較兩組患者臨床療效:治療組治愈3人,顯效13人,有效8人,無(wú)效6人,顯效率53.33%,總有效率80%。對(duì)照組治愈1人,顯效7人,有效10人,無(wú)效12人,顯效率27.67%,總有效率60%。具有統(tǒng)計(jì)學(xué)差異(P值等于0.028),治療組療效優(yōu)于對(duì)照組。3.8治療期間,治療組有1例出現(xiàn)胃脘部不適,1例出現(xiàn)月經(jīng)量增多,對(duì)照組有1例出現(xiàn)輕微腹瀉。兩組不良反應(yīng)發(fā)生率分別為6.67%、3.33%,差異無(wú)統(tǒng)計(jì)學(xué)意義(P值大于0.05)。4結(jié)論復(fù)方澤漆沖劑聯(lián)合走罐療法治療靜止期斑塊型銀屑病療效確切,且無(wú)明顯不良反應(yīng),值得臨床推廣。
[Abstract]:Objective to investigate 1 compound Zeqi Granules Combined with walking safety and efficacy of cupping therapy in the treatment of static plaque psoriasis, comprehensive evaluation of the clinical value of combined compound Zeqi granules walking cupping therapy, in order to promote.2 in late stage clinical methods 62 patients met the inclusion criteria of plaque psoriasis were randomly divided into treatment group and control the two group, 31 cases in each group. The treatment group was treated with compound Zeqi granules oral, topical Vaseline ointment and workingcan in skin lesions. The control group were treated with compound Zeqi granules plus Vaseline oral topical.2 weeks for 1 courses, a total of 4 courses of treatment. After 2 weeks of treatment, after 4 weeks, 6 weeks, the scores of PASI and pruritus degree were performed after 8 weeks and after treatment were compared between the two groups of single sign lesion severity score, TCM syndrome score, DLQI score, clinical efficacy, and observe the whole research process There is no adverse reaction to the end of the course of 3.1.3 results in this study, the treatment group of 1 people for work in strict accordance with the treatment time to transfer to the hospital, the control group had 1 people taking other drugs during treatment, so the loss of 2 people, finally 60 patients completed the clinical study on the treatment of two, 30 cases in each group. Two before treatment, skin lesions signs of severity score, PASI score, pruritus score, TCM syndrome score, DLQI score were not statistically significant (P values were greater than 0.05), with more than two groups of.3.2 lesions of patients with signs of severity score, compared with those before treatment, the treatment group and control group can improve the scaly skin lesions, infiltration, signs of erythema (P < 0.05); comparison between the two groups, the treatment group in improving the symptoms of scaly skin lesions than the control group (P = 0.006), the two groups in the improvement of skin erythema infiltration and signs of equivalent efficacy (P values were 澶т簬0.05).3.3涓ょ粍鎮(zhèn)ｈ，

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