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中國(guó)中醫(yī)科學(xué)院廣安門(mén)醫(yī)院心內(nèi)科治療冠心病合并非瓣膜性房顫組方規(guī)律分析

發(fā)布時(shí)間:2018-01-07 13:16

  本文關(guān)鍵詞:中國(guó)中醫(yī)科學(xué)院廣安門(mén)醫(yī)院心內(nèi)科治療冠心病合并非瓣膜性房顫組方規(guī)律分析 出處:《北京中醫(yī)藥》2017年03期  論文類型:期刊論文


  更多相關(guān)文章: 非瓣膜性房顫 冠心病 中醫(yī)傳承輔助平臺(tái) 中藥 組方規(guī)律


【摘要】:目的分析中國(guó)中醫(yī)科學(xué)院廣安門(mén)醫(yī)院心內(nèi)科治療冠心病合并非瓣膜性房顫患者的用藥特點(diǎn)及組方規(guī)律。方法收集2012年7月—2015年7月228例冠心病合并非瓣膜性房顫住院患者的臨床資料,基于中醫(yī)傳承輔助平臺(tái)V2.5軟件進(jìn)行統(tǒng)計(jì)分析。結(jié)果治療冠心病合并非瓣膜性房顫共涉及方劑408首,包含藥物309種。將支持度設(shè)置為61,置信度設(shè)置為0.6,得到常用藥物的組合模式24種,得到關(guān)聯(lián)規(guī)則13條。設(shè)置相關(guān)度為8,懲罰度為4,基于復(fù)雜網(wǎng)絡(luò)熵聚類的核心組合38種,基于熵層次聚類的治療冠心病合并非瓣膜性房顫的新方組合19個(gè)。結(jié)論中國(guó)中醫(yī)科學(xué)院廣安門(mén)心內(nèi)科治療冠心病合并非瓣膜性房顫以益氣養(yǎng)陰為主,輔以活血化瘀、健脾祛濕;在此基礎(chǔ)上通過(guò)復(fù)雜網(wǎng)絡(luò)熵聚類分析得出新方組合19個(gè),有待臨床的進(jìn)一步驗(yàn)證。
[Abstract]:Objective to analyze the clinical characteristics and prescription of cardiology in the treatment of coronary heart disease complicated with non-valvular atrial fibrillation in Guanganmen Hospital, Chinese Academy of traditional Chinese Medicine. Methods from July 2012 to July 2015, 228 cases of coronary heart disease were collected. Clinical data of inpatients with non-valvular atrial fibrillation. Results the treatment of coronary heart disease with non-valvular atrial fibrillation involved 408 prescriptions, including 309 kinds of drugs. The support degree was set to 61. The confidence degree is set to 0.6, 24 kinds of combination modes of common drugs are obtained, and 13 rules of association are obtained. The set correlation degree is 8, the penalty degree is 4, and the core combination based on complex network entropy clustering is 38 kinds. There are 19 new prescriptions for the treatment of coronary heart disease with non-valvular atrial fibrillation based on entropy hierarchical clustering. Conclusion the main treatment of coronary heart disease with non-valvular atrial fibrillation is to nourish qi and nourish yin in the treatment of coronary heart disease with non-valvular atrial fibrillation. Auxiliary to promote blood circulation and remove blood stasis, invigorate spleen and remove dampness; On this basis, 19 new combinations are obtained by entropy clustering analysis of complex networks, which need further clinical verification.
【作者單位】: 中國(guó)中醫(yī)科學(xué)院廣安門(mén)醫(yī)院南區(qū);中國(guó)中醫(yī)科學(xué)院廣安門(mén)醫(yī)院;北京中醫(yī)藥大學(xué);
【基金】:國(guó)家中醫(yī)藥管理局行業(yè)專項(xiàng)(201207001) 十二五重點(diǎn)領(lǐng)域研究專項(xiàng)(zz0808005)
【分類號(hào)】:R259
【正文快照】: 心房顫動(dòng)(房顫),指心房無(wú)序除極,正常生理電活動(dòng)喪失,導(dǎo)致心房無(wú)有效收縮,是最嚴(yán)重的心房電活動(dòng)紊亂,可以增加中風(fēng)和死亡風(fēng)險(xiǎn),其發(fā)病率隨年齡的增加而增加[1]。冠狀動(dòng)脈粥樣硬化性心臟病(冠心病)指冠狀動(dòng)脈粥樣硬化使血管腔狹窄或阻塞,或因冠狀動(dòng)脈功能性改變(痙攣)導(dǎo)致心肌缺

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