本文關鍵詞：五運六氣稟賦對兒童過敏性紫癜發(fā)病的相關性研究　出處：《廣州中醫(yī)藥大學》2017年碩士論文　論文類型：學位論文

  更多相關文章： 過敏性紫瘢 五運六氣 治未病

【摘要】：目的:本文通過將運氣稟賦體質與過敏性紫癜相結合,以五行生克制化和治未病思想作為防治理論,探討運氣稟賦因素對過敏性紫癜發(fā)病、發(fā)展的影響,從而尋找廣州中醫(yī)藥大學第一附屬醫(yī)院兒科住院病人中過敏性紫癜的病人與非過敏性紫癜患兒的運氣稟賦差異特點,以期發(fā)現(xiàn)該病致病的危險因素或保護因素,更好地規(guī)避風險、指導治療。方法:收集廣州中醫(yī)藥大學第一附屬醫(yī)院兒科住院部的全部患兒,出生日期在1996至2010年,其中過敏性紫癜患兒共350例,以此作為實驗組,并以同年齡段在該科室住院的非過敏性紫癜患兒為對照組,共計約14418例。采用回顧性病例對照的研究方法,分別比較兩組之間的各個稟賦因素和運氣稟賦體質的差異,推測發(fā)生過敏性紫癜可能存在的易感或保護因素。結果:在五運當中,分別對兩組十天干進行比較,結果提示兩者無統(tǒng)計學意義(P=0.087);對兩組合并后的五行進行比較,既分別比較水行、木行、火行、土行、金行五行,結果提示兩者在木運、金運和土運間具有統(tǒng)計學意義(P0.05);以陰陽屬性為原則,對兩者進行歸納比較,結果提示其在陰屬性、中(土)間具有統(tǒng)計學意義(P0.05)。在六氣當中,分別對兩組十二地支進行比較,結果提示陽明燥金司天(P=0.0079)、太陽寒水司天(P=0.0058)、太陰濕土司天(P=0.0058)及太陽寒水在泉(P=0.0092)具有統(tǒng)計學意義;而合并后的三陰三陽(P=0.451)及陰陽屬性(P=0.425)無統(tǒng)計學意義。而在運氣稟賦因素的協(xié)同作用下,對兩組運氣稟賦進行比較,結果提示太金-太陽寒水(P=0.0000)、少木-少陽相火(P:=0.0001)、少土-太陰濕土(P=0.0000)、少土-太陽寒水(P=0.0001)具有統(tǒng)計學意義。結論:過敏性紫癜的易感因素包括陽明燥金司天、太陽寒水司天、歲運-中(土)、歲運-土行和太金-太陽寒水;保護因素包括太陰濕土司天、太陽寒水在泉、歲運-陰、歲運-木行、歲運-金行、少木-少陽相火、少土-太陰濕土和少土-太陽寒水,提示紫癜患兒的體質具有體質偏陽、脾腎虧虛和稟賦逆四時生長規(guī)律等特點。
[Abstract]:Objective: to explore the influence of luck endowment factors on the pathogenesis and development of Henoch-Schonlein purpura (Hpura) by combining luck endowment with allergic purpura and taking the thought of "Wuxingsheng restraint" and "preventing and treating diseases" as the prevention and treatment theory. In order to find out the risk factors or protective factors of allergic purpura in pediatric inpatients in the first affiliated Hospital of Guangzhou University of traditional Chinese Medicine, the difference of luck between the patients with Henoch-Schonlein purpura and children with non-Henoch-Schonlein purpura was found. Methods: all the children in the Department of Pediatrics of the first affiliated Hospital of Guangzhou University of traditional Chinese Medicine were collected from 1996 to 2010. Among them 350 cases of Henoch-Schonlein purpura were used as experimental group and non-Henoch-Schonlein purpura children who were hospitalized in the same age department as control group. A total of 14418 cases were studied by retrospective case-control study to compare the differences of the endowment factors and the physique of luck between the two groups. The results showed that there was no significant difference between the two groups in ten days, the results showed that there was no statistical significance between the two groups. The comparison of the five elements of the two groups after the merger, namely water row, wood line, fire line, soil line, gold line five elements, the results suggest that the two groups in wood transport, gold transport and soil transport between the statistical significance of P0.05; Based on the principle of yin and yang, the results show that there is statistical significance between them in the Yin attribute and the middle (earth). In the six Qi, the two groups of 12 ground branches are compared respectively. The results suggested that Yangming dryness Jinsitiandao (P0. 0079) and sun cold water (P0. 0058). There was statistical significance between Taiyin and wet Tusi (P0. 0058) and solar cold water (P0. 0092). However, there was no statistical significance between the combined three yin and three yang (P _ (0.451)) and the attribute of Yin and Yang (P _ (0.425)). However, the luck endowment of the two groups was compared under the synergistic effect of the factors of luck endowment. The results suggest that Taijin-Sun cold water (P0. 00000), Shaomu-Shaoyang phase fire (P0. 0001), and soil-too wet soil (P0. 0000). Conclusion: the susceptible factors of allergic purpura include Yangming dryness Jinsitian, solar cold water days, years of transport-middle (soil). Years of transport-soil line and Taijin-sun cold water; Protective factors include too wet toast days, the sun cold water in spring, year transport-yin, year-transport-wood line, year-transport-gold line, less wood-less sun fire, less soil-too wet soil and less earth-sun cold water. It is suggested that the constitution of the children with purpura has the characteristics of yang deficiency of spleen and kidney deficiency of spleen and kidney and growth law of endowment.
【學位授予單位】：廣州中醫(yī)藥大學
【學位級別】：碩士
【學位授予年份】：2017
【分類號】：R272

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