本文關(guān)鍵詞：慢性乙型肝炎證候虛實(shí)分類與外周血淋巴細(xì)胞亞群的關(guān)系　出處：《中國(guó)中醫(yī)基礎(chǔ)醫(yī)學(xué)雜志》2017年05期 　論文類型：期刊論文

  更多相關(guān)文章： 慢性乙型肝炎 免疫狀態(tài) 中醫(yī)虛實(shí)分類 T淋巴細(xì)胞 B淋巴細(xì)胞 NK細(xì)胞

【摘要】：目的:了解慢性乙型肝炎(CHB)患者中醫(yī)證候虛實(shí)分類與外周血淋巴細(xì)胞亞群之間的關(guān)系。方法:將CHB患者進(jìn)行證候虛證、實(shí)證及虛實(shí)夾雜證分類,并檢測(cè)其外周血T、B細(xì)胞及自然殺傷(NK)細(xì)胞亞群,并對(duì)其3個(gè)證型組的指標(biāo)進(jìn)行分析。結(jié)果:CHB虛證、實(shí)證及虛實(shí)夾雜3個(gè)組的CD4~+T細(xì)胞百分比均較對(duì)照組低;CD8~+T細(xì)胞百分比由高至低依次為實(shí)證組、虛實(shí)夾雜證組、對(duì)照組、虛證組,實(shí)證組CD4~+/CD8~+比值顯著低于虛證組或?qū)φ战M,3個(gè)組的B細(xì)胞百分比均高于對(duì)照組,NK細(xì)胞百分比低于對(duì)照組。結(jié)論:CHB存在著免疫調(diào)節(jié)紊亂,證候虛實(shí)分類與外周血淋巴細(xì)胞亞群之間存在一定的相關(guān)性,中醫(yī)虛實(shí)證辨證結(jié)合免疫功能檢測(cè)具有一定的臨床意義。
[Abstract]:Objective: to understand the relationship between TCM syndrome deficiency and peripheral blood lymphocyte subsets in patients with chronic hepatitis B. methods: CHB patients were divided into syndromes deficiency syndrome, positive syndrome and deficiency and excess syndrome. The subsets of T B cells and NK cells in peripheral blood were detected, and the indexes of the three syndromes were analyzed. The percentages of CD4T cells in the three groups were lower than those in the control group. The percentage of CD8 ~ T cells was significantly lower in the group of deficiency syndrome than that in the group of deficiency syndrome or control group, and the ratio of CD4 ~ / CD8 ~ ~ in the group of deficiency syndrome and deficiency syndrome was significantly lower than that in the group of deficiency syndrome or control group in the order of CD8T cell percentage from high to low. The percentage of B cells in the three groups was higher than that in the control group, and the percentage of NK cells in the three groups was lower than that in the control group. There is a certain correlation between the classification of deficiency and deficiency of syndrome and lymphocyte subsets in peripheral blood. It is of certain clinical significance to detect the deficiency and deficiency of syndrome combined with immune function in TCM.
【作者單位】： 桂林醫(yī)學(xué)院附屬醫(yī)院;
【基金】：國(guó)家自然科學(xué)基金資助項(xiàng)目(81260602)-HBV感染不同免疫狀態(tài)證候要素與外周血淋巴細(xì)胞亞群的關(guān)系
【分類號(hào)】：R259
【正文快照】： 我國(guó)一般人群乙型肝炎病毒(hepatitis B virus,HBV)流行率為7.18%,估計(jì)約9300萬人為慢性HBV感染,其中慢性乙型肝炎(chronic hepatitis BCHB)患者約2000萬例[1]。中西醫(yī)結(jié)合防治CHB是我國(guó)獨(dú)特的方法,中醫(yī)藥對(duì)人體免疫功能的影響是大多數(shù)中藥抗病毒的主要機(jī)制之一,其治療優(yōu)勢(shì)在

【相似文獻(xiàn)】

相關(guān)期刊論文 前8條

1 杜文杰 ,徐方明;軟肝煎治療慢性乙型肝炎肝纖維化82例——附西藥治療60例對(duì)照觀察[J];浙江中醫(yī)雜志;2002年05期

2 高連印,車念聰,付修文,錢英;槲芪散治療慢性乙型病毒性肝炎30例療效分析[J];北京中醫(yī);2001年03期

3 林屹;慢性乙型病毒性肝炎的中醫(yī)藥治療近況[J];安徽中醫(yī)學(xué)院學(xué)報(bào);2004年01期

4 黃敏華;;蛇虎丹七湯治療慢性乙型肝炎肝纖維化69例[J];浙江中醫(yī)雜志;2006年12期

5 徐惠祥;肝脾康治療慢性乙型肝炎合并脂肪肝32例[J];中醫(yī)藥學(xué)報(bào);2000年05期

6 彭小輝;;中藥保留灌腸治療慢性重型乙型肝炎的護(hù)理體會(huì)[J];湖南中醫(yī)雜志;2011年04期

7 張杰;朱肖鴻;;中藥治療黃疸型慢性乙型病毒性肝炎療效觀察[J];深圳中西醫(yī)結(jié)合雜志;2013年01期

8 ;[J];;年期

，

本文編號(hào)：1373221