本文關鍵詞：張氏百草傷膏改制凝膠劑結合超聲電導透射治療膝痹病的療效觀察　出處：《中華中醫(yī)藥雜志》2017年06期 　論文類型：期刊論文

  更多相關文章： 張氏百草傷膏 凝膠劑 超聲電導透射 膝骨性關節(jié)炎 療效

【摘要】：目的:觀察張氏百草傷膏改制凝膠劑結合超聲電導透射治療膝痹病(KOA)的臨床療效。方法:KOA患者240例,隨機分為3組:試驗組采用超聲電導透射百草傷膏凝膠貼片治療,陽性藥物對照組采用超聲電導透射雙氯酚酸二乙胺凝膠片治療,百草傷膏組采用傳統(tǒng)黑膏藥百草傷膏外貼治療,分別對3組治療前及治療后1、2、4周VAS疼痛評分、WOMAC骨關節(jié)炎指數以及安全性進行比較。結果:3組治療前后VAS評分、膝關節(jié)WAMAC評分比較,差異均有統(tǒng)計學意義(P0.05),其臨床療效顯著。試驗組與百草傷膏組治療后各觀察時間段WAMAC評分差異均有統(tǒng)計學意義(P0.05),表明百草傷膏凝膠劑在膝關節(jié)臨床療效方面優(yōu)于百草傷膏。試驗組較陽性藥物對照組VAS評分、WOMAC評分在第4周顯著降低(P0.05),表明試驗組在臨床療效上維持時間更長。不良反應觀察試驗組有1例出現局部皮疹,陽性藥物對照組5例,百草傷膏組22例,差異有統(tǒng)計學意義(P0.05),表明試驗組具有更好的安全性。結論:與傳統(tǒng)黑膏藥比較,張氏百草傷膏凝膠劑結合超聲電導透射治療KOA在早、中期是一種臨床療效顯著、藥效持續(xù)時間更長、安全性更高的中藥外用方法。
[Abstract]:Objective: to observe the clinical effect of Zhang's Bancao shangshang ointment modified gel combined with ultrasonic conductance transmission in the treatment of knee arthralgia (KOAA). Three groups were randomly divided into three groups: the experimental group was treated with ultrasonic conductance transmission baccalophen ointment gel patch, and the positive drug control group was treated with ultrasonic conductance transmission dichlorophenol acid diethylamine gel tablet. The treatment group was treated with the traditional black plaster Bricao shangshang ointment. The pain scores of VAS were evaluated before and after 1 ~ 2 weeks of treatment in 3 groups. WOMAC osteoarthritis index and safety were compared. Results there were significant differences in VAS score and knee joint WAMAC score before and after treatment in the three groups (P 0.05). The clinical efficacy was remarkable. The WAMAC scores of the experimental group and the BCSO group were significantly different after treatment (P0.05). The results showed that the clinical curative effect of Brichaoshang ointment was better than that of the control group. The VAS score and WOMAC score of the test group were significantly lower than those of the positive control group in the 4th week (P 0.05). The results showed that the clinical efficacy of the trial group was longer than that of the control group. There were 1 case of local rash in the adverse reaction observation group, 5 cases in the positive drug control group and 22 cases in the BCSO group. The difference was statistically significant (P 0.05), which indicated that the experimental group had better safety. Conclusion: compared with the traditional black plaster, the combination of Zhang's Broccoli paste and ultrasonic conductance transmission therapy is early in the treatment of KOA. Medium-term is a more effective, longer-lasting and more safe method for external use of traditional Chinese medicine.
【作者單位】： 杭州市富陽中醫(yī)骨傷醫(yī)院;北京中美聯醫(yī)學科學研究院;
【基金】：浙江省中西醫(yī)結合骨關節(jié)病研究重點科技創(chuàng)新團隊項目(No.2011R50022-15) 浙江省中醫(yī)藥重點學科建設項目(No.2012-XK-D03)~~
【分類號】：R274.9
【正文快照】： 膝痹病,即膝關節(jié)骨性關節(jié)炎(knee osteoarthritis,KOA),是一種臨床常見的由于關節(jié)軟骨退行性變引起的以關節(jié)疼痛和功能障礙為主要臨床表現的疾病。在老年化社會日益加重的今天,其發(fā)病率呈不斷上升趨勢。張氏百草傷膏為富陽中醫(yī)骨傷醫(yī)院傳統(tǒng)外用制劑,治療KOA療效肯定,但亦存在

【相似文獻】

相關期刊論文 前1條

1 劉s，

本文編號：1372019