本文關(guān)鍵詞：循經(jīng)取穴針刺對慢性穩(wěn)定型心絞痛患者癥狀及血清CRP、BNP的影響研究　出處：《成都中醫(yī)藥大學(xué)》2016年碩士論文　論文類型：學(xué)位論文

  更多相關(guān)文章： 針刺 循經(jīng)取穴 慢性穩(wěn)定型心絞痛 臨床療效評價 C-反應(yīng)蛋白 腦鈉肽

【摘要】：目的本研究以慢性穩(wěn)定型心絞痛(Chronic Stable Angina Pectoris, CSAP)為研究對象,評價循經(jīng)取穴與非循經(jīng)取穴針刺治療對心絞痛患者的臨床癥狀及血清腦鈉肽(Brain Natriuretic Peptide, BNP)和C-反應(yīng)蛋白(C-Reactive Protein, CRP)水平的影響。方法本研究共納入CSAP患者36例,隨機分為A、B兩組。兩組均進行10次針刺治療。A組取手厥陰心包經(jīng)內(nèi)關(guān)穴和手少陰心經(jīng)通里穴,B組取手陽明大腸經(jīng)陽溪穴和偏歷穴。針刺治療前后分別以心絞痛發(fā)作次數(shù)、加拿大心臟病學(xué)會(Canada Cardiology Ssociation, CCS)心絞痛程度分級和視覺模擬評分(Visual Analogue Scale,VAS)評價患者心絞痛癥狀的變化情況,采用酶聯(lián)免疫吸附測定法(Enzyme Linked Immuno Sorbent Assay,ELISA)觀察循經(jīng)與非循經(jīng)兩種取穴方法針刺對患者血清BNP和CRP水平的影響。所有數(shù)據(jù)均采用SPSS17.0統(tǒng)計軟件進行分析處理。結(jié)果1.所納入的36例受試者均完成了本試驗研究。2.兩組受試者基線一致,具有可比性(p0.05)。3.兩種取穴針刺方法對CSAP患者癥狀的影響(1)與針刺前相比,循經(jīng)取穴針刺可顯著降低CSAP患者的心絞痛發(fā)作次數(shù)及VAS評分,差異具有統(tǒng)計學(xué)意義(p0.05),非循經(jīng)取穴針刺可改善CSAP患者VAS評分,差異有統(tǒng)計學(xué)意義(p0.05)。(2)兩種取穴針刺方法對CCS心絞痛嚴(yán)重程度分級、發(fā)作次數(shù)改善值、程度分級改善值及VAS改善值無顯著差異(p0.05)。4.兩種取穴針刺方法對心絞痛患者血清CRP、BNP水平的影響兩組針刺治療對心絞痛患者血清CRP、BNP水平均無顯著影響(p0.05)；兩種針刺方法對心絞痛患者血清CRP、BNP水平影響無顯著組間差異(p0.05)。結(jié)論1.循經(jīng)取穴和非循經(jīng)取穴兩種方案均可降低心絞痛患者的VAS評分,循經(jīng)取穴針刺還可以減少心絞痛患者的心絞痛發(fā)作次數(shù)。2.由于療程較短,樣本量少,兩種取穴方案對心絞痛患者血清CRP、BNP水平均無明顯影響。3.試驗中無明顯不良事件及心血管事件發(fā)生。
[Abstract]:Objective to study chronic Stable Angina Pectoris (CSAP) of chronic stable angina pectoris. Objective: to evaluate the clinical symptoms and brain Natriuretic Peptide of patients with angina pectoris treated with acupoints along meridian and non-meridian acupoints. Methods 36 patients with CSAP were randomly divided into three groups. Group B. both groups were treated with acupuncture for 10 times. Group A took out the points of pericardial meridian of Hand-Jueyin and Tongli of Hand-Shaoyin Meridian. Group B took hand Yangming large intestine meridian Yangxi and Bianli points. Before and after acupuncture treatment with angina pectoris attack times. Canada Cardiology Ssociation. The changes of angina pectoris symptoms were evaluated by visual Analogue scale scale score and visual analogue score (VAS) in patients with angina pectoris. Enzyme Linked Immuno Sorbent Assay were determined by enzyme-linked immunosorbent assay (Elisa). Elsa). To observe the effect of acupuncture on serum BNP and CRP levels of patients with acupoints taken along meridian and non-meridian meridians. All data were analyzed by SPSS17.0 statistical software. Results 1. 2. The baseline of the two groups was the same. The effect of two acupuncture methods on the symptoms of CSAP patients was compared with that before acupuncture. Acupuncture along the meridian can significantly reduce the frequency of angina pectoris attack and VAS score in patients with CSAP, the difference is statistically significant (P 0.05). Non-meridian acupoint acupuncture can improve the VAS score of patients with CSAP, the difference is statistically significant (P 0.05. 0. 0. 0. 2) the two acupuncture methods for CCS angina pectoris severity classification. There was no significant difference in the improvement value of attack frequency, degree grade and VAS. The two acupuncture methods were used to treat the serum CRP of patients with angina pectoris. The effect of BNP level on the serum CRP level of patients with angina pectoris was not significantly affected by acupuncture therapy in both groups (P 0.05). Two acupuncture methods were used to treat serum CRP in patients with angina pectoris. There was no significant difference in the level of BNP between the two groups. Conclusion 1. The VAS score of patients with angina pectoris can be decreased by both the acupoint extraction along the meridian and the non-meridian acupoints. 2. Acupuncture along the meridian can also reduce the number of angina pectoris attacks in patients with angina pectoris. 2. Because of the short course of treatment, the sample size is small, the two methods of acupoint extraction in patients with angina pectoris serum CRP. No significant adverse events or cardiovascular events occurred in the trial.
【學(xué)位授予單位】：成都中醫(yī)藥大學(xué)
【學(xué)位級別】：碩士
【學(xué)位授予年份】：2016
【分類號】：R246.1

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